The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients
Abstract
We compared insulin-requiring diabetic outpatients (n = 49) with normal controls (n = 42) for indices of hypothalamic-pituitary-adrenal (HPA) axis activity. Diabetic patients showed significantly elevated 9 a.m. plasma levels of cortisol as well as significantly elevated plasma levels of cortisol and adrenocorticotropic hormone (ACTH) at both 4 p.m. before and 4 p.m. after dexamethasone. Also, there was a significant correlation between postdexamethasone plasma levels of ACTH and duration of diabetes. These results suggest that HPA-axis dysregulation is found among diabetic outpatients. The possible psychiatric implications are discussed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis in association with hyperinsulinemia is frequently found in patients with type 1 and type 2 diabetes mellitus and in subjects with abdominal adiposity.”
From Supraphysiological Hyperinsulinemia Acutely Increases Hypothalamic-Pituitary-Adrenal Secretory Activity in Humans (1999) · cites this paper as [1]
Citations
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Endicott, J. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770310043002 · Cited by 5,697
Carroll, B. J. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780260017001 · Cited by 2,243
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor.
Gold, P., Chrousos, G., Kellner, C., Post, R., Roy, A., Augerinos, P., Schulte, H., Oldfield, E., & Loriaux, D. (1984) · American Journal of Psychiatry · doi:10.1176/ajp.141.5.619 · Cited by 460
Self-citationThe Social Grading of Occupations. A New Approach and Scale.
Svalastoga, K., Goldthorpe, J. H., & Hope, K. (1975) · Population Studies · doi:10.2307/2173945 · Cited by 381
An Alternative Method of Grading Diabetic Retinopathy
Klein, R., Klein, R., Magli, Y. L., Brothers, R. J., Meuer, S. M., Moss, S. E., & Davis, M. D. (1986) · Ophthalmology · doi:10.1016/s0161-6420(86)33606-6 · Cited by 306
Popkin, M. K. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800250078010 · Cited by 217
Catecholamine effects upon rat hypothalamic corticotropin-releasing hormone secretion in vitro.
Calogero, A. E., Gallucci, W. T., Chrousos, G. P., & Gold, P. W. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113687 · Cited by 188
Hypothalamic Monoamine Control of Stress-Induced Adrenocorticotropin Release in the Rat*
Smythe, G. A., BRADSHAW, J. E., & VINING, R. F. W. (1983) · Endocrinology · doi:10.1210/endo-113-3-1062 · Cited by 154
Hypothalamic-Pituitary-Adrenocortical Activity in Patients With Diabetes Mellitus
Cameron, O. G. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790220080013 · Cited by 149
Dexamethasone suppression test: a review of contemporary confusion.
Carroll, B. J. (1985) · PubMed · Cited by 139
SZAFARCZYK, A., Alonso, G., IXART, G., Malaval, F., & ASSENMACHER, I. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.249.2.e219 · Cited by 117
Prevalence of diabetes in a manic-depressive population
Lilliker, S. L. (1980) · Comprehensive Psychiatry · doi:10.1016/0010-440x(80)90030-9 · Cited by 115
The Social Grading of Occupations. A New Approach and Scale.
Coxon, A. P. M., Goldthorpe, J. H., & Hope, K. (1975) · Journal of the Royal Statistical Society Series A (General) · doi:10.2307/2345237 · Cited by 115
Guillaume, V., Conte‐Devolx, B., SZAFARCZYK, A., Malaval, F., Pares-Herbute, N., Grino, M., Alonso, G., ASSENMACHER, I., & Oliver, C. (2008) · Neuroendocrinology · doi:10.1159/000124811 · Cited by 106
Cummings, S., & Seybold, V. S. (2008) · Neuroendocrinology · doi:10.1159/000124965 · Cited by 102
Abnormal Results of Dexamethasone Suppression Tests in Nondepressed Patients With Diabetes Mellitus
Hudson, J. I. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790220076012 · Cited by 91
The effect of stress on the dexamethasone suppression test
Ceulemans, D. L. S., Westenberg, H. G. M., & van Praag, H. M. (1985) · Psychiatry Research · doi:10.1016/0165-1781(85)90013-7 · Cited by 79
Hypercortisolism in Diabetes Mellitus
Cameron, O. G., Thomas, B. L., Tiongco, D., Hariharan, M., & Greden, J. F. (1987) · Diabetes Care · doi:10.2337/diacare.10.5.662 · Cited by 62
Relative insulin insensitivity and cortisol secretion in depressed patients
Nathan, R. S., Sachar, E. J., Asnis, G. M., Halbreich, U. M., & Halpern, F. S. (1981) · Psychiatry Research · doi:10.1016/0165-1781(81)90031-7 · Cited by 62
Dexamethasone Suppression Test
Carroll, B. J. (1984) · Springer eBooks · doi:10.1007/978-94-011-6725-3_1 · Cited by 54
Roy, A., Pickar, D., Linnoila, M., Chrousos, G. P., & Gold, P. W. (1987) · Psychiatry Research · doi:10.1016/0165-1781(87)90083-7 · Cited by 48
Self-citationDiabetes-induced changes in monoamine concentrations of rat hypothalamic nuclei
Bitar, M. S., Koulu, M., & Linnoila, M. (1987) · Brain Research · doi:10.1016/0006-8993(87)90707-4 · Cited by 41
Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls
Roy, A., Gold, P. W., Pickar, D., Wolkowitz, O. M., Chrousos, G. P., & Paul, S. M. (1986) · Journal of Affective Disorders · doi:10.1016/0165-0327(86)90032-7 · Cited by 36
Self-citationHandbook of Psychiatric Diagnostic Procedures
Schwab, J. J. (1985) · Psychosomatics · doi:10.1016/s0033-3182(85)72805-8 · Cited by 19
Effects of lithium administration on plasma catecholamines
Grof, E., Brown, G. M., Grof, P., & Loon, G. R. V. (1986) · Psychiatry Research · doi:10.1016/0165-1781(86)90095-8 · Cited by 8
Research works printed but not linked: 1
- Gold, 1986, The corticotropin releasing factor stimulation test: Implications for the diagnosis and pathophysiology of hypercortisolism in primary affective disor ders and Cushing's disease, New England Journal of Medicine, 314, 1330
Cited by
Sorted by citations
Cortisol Secretion in Patients With Type 2 Diabetes
Chiodini, I., Adda, G., Scillitani, A., Coletti, F., Morelli, V., Lembo, S. D., Epaminonda, P., Masserini, B., Beck‐Peccoz, P., Orsi, E., et al. (2006) · Diabetes Care · doi:10.2337/dc06-1267 · Cited by 243
Hypercortisolemic Depression Is Associated With Increased Intra-Abdominal Fat
Weber-Hamann, B., Hentschel, F., Kniest, A., Deuschle, M., Colla, M., Lederbogen, F., & Heuser, I. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200203000-00010 · Cited by 219
Krause, M. P., Riddell, M. C., & Hawke, T. J. (2010) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2010.00699.x · Cited by 190
Elevated late-night salivary cortisol levels in elderly male type 2 diabetic veterans.
Liu, H., Bravata, D. M., Cabaccan, J., Raff, H., & Ryzen, E. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02395.x · Cited by 178
Sarcopenia in Autoimmune and Rheumatic Diseases: A Comprehensive Review
An, H. J., Tizaoui, K., Terrazzino, S., Cargnin, S., Lee, K. H., Nam, S. W., Kim, J., Yang, J. W., Lee, J. Y., Smith, L., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165678 · Cited by 142
Metadata
- Authors
- Roy, M., Collier, B., & Roy, A.
- Affiliations
- National Eye Institute (US)
- Corresponding author
- Roy, Monique
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 1990-01
- Volume
- 31
- Issue
- 1
- Pages
- 31-37
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2049915127
- Cited by
- 107
- References
- 26
- Citations by year
- 2025: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 4 · 2014: 2 · 2013: 8 · 2012: 2
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- hypothalamic-pituitary-adrenal axis, HPA axis dysregulation, diabetes mellitus, type 1 diabetes, insulin-treated diabetes, cortisol, ACTH, dexamethasone suppression test, diabetes duration, psychiatric implications
- MeSH terms
- Adrenocorticotropic Hormone, Aged, Circadian Rhythm, Depressive Disorder, Dexamethasone, Diabetes Mellitus, Type 1, Female, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Male, Pituitary-Adrenal System
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
