The DOI matches its Crossref record.
The cytoplasmic ribosomal RNAs of Plasmodium spp
Abstract
Plasmodium spp maintain several structurally distinct sets of ribosomal RNA genes whose expression is developmentally regulated. This feature sets them apart from all other eukaryotes studied to date. In this review, Thomas McCutchan, Jun Li, Glenn McConkey, John Rogers and Andy Waters give an account of the progress in our understanding of this unusual phenomenon as it relates to the biology of the parasite. They also outline an interesting turnabout in scientific direction involving the use of the parasite as an important new model for the study of the eukaryotic ribosome.
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“The 18S rRNA gene was chosen as the target since it contains both highly conserved and variable regions, and at least five copies of the gene are dispersed on separate chromosomes of the Plasmodium genome (11, 20).”
From Real-Time PCR for Detection and Identification of Plasmodium spp (2005) · cites this paper as [20]
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Cited by
Sorted by citations
Real-Time PCR for Detection and Identification of Plasmodium spp
Mangold, K. A., Manson, R. U., Koay, E. S. C., Stephens, L., Regner, M., Thomson, R. B., Peterson, L. R., & Kaul, K. L. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.5.2435-2440.2005 · Cited by 278
Metadata
- Authors
- McCutchan, T. F., Li, J., McConkey, G. A., Rogers, M. J., & Waters, A. P.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- McCutchan, T.F.
- Venue
- Parasitology Today
- Publisher
- Elsevier BV
- Published
- 1995-04
- Volume
- 11
- Issue
- 4
- Pages
- 134-138
- ISSN
- 0169-4758 (ISSN-L)
- OpenAlex
- W2089509050
- Cited by
- 96
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 5 · 2012: 1
- FWCI
- 11.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Parasitology Today (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
- Keywords
- Plasmodium, ribosomal DNA, developmental gene expression, 80S ribosome, gene expression regulation
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