The DOI matches its Crossref record; 23 of the 24 references it cites were found in a registry or an index.
Muscarinic receptor activation facilitates the induction of long-term potentiation (LTP) in the rat dentate gyrus
Abstract
Bath application of two different concentrations of muscarine produced two different effects on evoked responses in the dentate gyrus of rat hippocampal slices. A concentration of 1 microM muscarine did not affect the evoked population spike or excitatory postsynaptic potential (EPSP), but facilitated the induction of LTP. In contrast, a concentration of 10 microM muscarine depressed both the population spike and EPSP, but had no effect on LTP induction. The M1 muscarinic receptor antagonist pirenzepine (1 microM) blocked the muscarine-induced facilitation of LTP, but had no effect on the depression of evoked responses. These data suggest that activation of M1 receptors can facilitate the induction of LTP.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The enhancement of long-term encoding could be at least partially mediated by the cholinergic enhancement of long-term potentiation in the hippocampus (Blitzer et al., 1990; Burgard and Sarvey, 1990; Auerbach and Segal, 1994; Isaac et al., 2009).”
From Modes and models of forebrain cholinergic neuromodulation of cognition (2011) · cites this paper as Burgard and Sarvey, 1990
Citations
Cites
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424
Pirenzepine distinguishes between different subclasses of muscarinic receptors
Hammer, R., Berrie, C. P., Birdsall, N. J. M., Burgen, A. S. V., & Hulme, E. C. (1980) · Nature · doi:10.1038/283090a0 · Cited by 1,273
Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes
Peralta, E. G., Ashkenazi, A., Winslow, J. W., Ramachandran, J., & Capon, D. J. (1988) · Nature · doi:10.1038/334434a0 · Cited by 658
Frotscher, M., & Léránth, C. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902390210 · Cited by 600
Localization of a family of muscarinic receptor mRNAs in rat brain
Buckley, N. J., Bonner, T. I., & Brann, M. R. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-12-04646.1988 · Cited by 478
Doods, H. N., Mathy, M. J., Davidesko, D., van Charldorp, K. J., Jonge, A. D., & van Zwieten, P. A. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39062-2 · Cited by 440
Acetylcholine Mediates a Slow Synaptic Potential in Hippocampal Pyramidal Cells
Cole, A. E., & Nicoll, R. A. (1983) · Science · doi:10.1126/science.6612345 · Cited by 374
Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain
Mash, D. C., & Potter, L. T. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90280-0 · Cited by 316
The role of protein kinase C in long-term potentiation: a testable model
Linden, D. J., & Routtenberg, A. (1989) · Brain Research Reviews · doi:10.1016/0165-0173(89)90004-0 · Cited by 291
Cortés, R., Probst, A., Tobler, H.-J., & Palacios, J. M. (1986) · Brain Research · doi:10.1016/0006-8993(86)90449-x · Cited by 286
Dutar, P., & Nicoll, R. A. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-11-04214.1988 · Cited by 251
Gil, D. W., & Wolfe, B. B. (1985) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20880-1 · Cited by 217
Muscarinic cholinergic receptor subtypes in the rat brain. I. Quantitative autoradiographic studies
Cortés, R., & PALACIOS, J. M. (1986) · Brain Research · doi:10.1016/0006-8993(86)90448-8 · Cited by 211
Dahl, D. R., & Sarvey, J. M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.12.4776 · Cited by 171
Self-citationLong-term potentiation: studies in the hippocampal slice
Sarvey, J. M., Burgard, E. C., & Decker, G. (1989) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(89)90016-2 · Cited by 118
Self-citationMüller, W. S., & Misgeld, U. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90381-2 · Cited by 100
Carbachol depresses synaptic responses in the medial but not the lateral perforant path
Kahle, J. S., & Cotman, C. W. (1989) · Brain Research · doi:10.1016/0006-8993(89)90554-4 · Cited by 87
Burgard, E. C., Decker, G., & Sarvey, J. M. (1989) · Brain Research · doi:10.1016/0006-8993(89)91199-2 · Cited by 72
Self-citationPiercey, M. F., Vogelsang, G. D., Franklin, S. R., & Tang, A. H. (1987) · Brain Research · doi:10.1016/0006-8993(87)91186-3 · Cited by 68
Central cholinergic pathways and learning and memory processes: Presynaptic aspects
Durkin, T. (1989) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(89)90216-8 · Cited by 61
Audigier, S., Wang, J. K., & Greengard, P. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.8.2859 · Cited by 58
Muscarinic receptor activation stimulates B-50/GAP43 phosphorylation in isolated nerve growth cones
Hooff, C. O. M. V., Graan, P. N. E. D., Oestreicher, A. B., & Gispen, W. H. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-11-03753.1989 · Cited by 45
Bartus, R. T., Flicker, C., Dean, R. L., Fisher, S. K., Pontecorvo, M. J., & Figueiredo, J. C. (1986) · Progress in brain research · doi:10.1016/s0079-6123(08)64315-0 · Cited by 40
Research works printed but not linked: 1
- Burgard, 1989, Muscarinic receptor activation modulates long-term potentiation (LTP) and isoproterenol-induced long-lasting potentiation (ILLP) in rat dentate gyrus, Pharmacologist, 31, 135
Cited by
Sorted by citations
Modes and models of forebrain cholinergic neuromodulation of cognition
Hasselmo, M. E., & Sarter, M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.104 · Cited by 733
Huerta, P. T., & Lisman, J. E. (1995) · Neuron · doi:10.1016/0896-6273(95)90094-2 · Cited by 673
Huerta, P. T., & Lisman, J. E. (1993) · Nature · doi:10.1038/364723a0 · Cited by 564
Neuromodulation and cortical function: modeling the physiological basis of behavior
Hasselmo, M. E. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(94)00113-t · Cited by 557
Hasselmo, M. E., & McGaughy, J. (2004) · Progress in Brain Research · doi:10.1016/s0079-6123(03)45015-2 · Cited by 525
Metadata
- Authors
- Burgard, E. C., & Sarvey, J. M.
- Affiliations
- Uniformed Services University of the Health Sciences (US)
- Corresponding author
- Sarvey, John M.
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 1990-08
- Volume
- 116
- Issue
- 1-2
- Pages
- 34-39
- ISSN
- 0304-3940 (ISSN-L)
- OpenAlex
- W2072926455
- Cited by
- 188
- References
- 24
- Citations by year
- 2026: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 5 · 2013: 1 · 2012: 10
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01ns023865-07)
- National Institute of Neurological Disorders and Stroke (NS-23865)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Keywords
- muscarinic receptors, M1 muscarinic receptor, long-term potentiation, LTP induction, dentate gyrus, hippocampus, muscarine, pirenzepine, excitatory postsynaptic potentials, synaptic plasticity
- MeSH terms
- Animals, Electric Stimulation, Evoked Potentials, Hippocampus, Kinetics, Muscarine, Pirenzepine, Receptors, Muscarinic, Rats, In Vitro Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
