The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis
Abstract
Exocytosis of neurosecretory granules from dendrites of magnocellular neurons can be visualized electron microscopically after incubation of hypothalamic brain slices in media containing 1.2 mM tannic acid, which stabilizes extracellular peptidergic granule cores, and permits their immunocytochemical identification. Morphometric analysis of stimulated slices demonstrates that exocytosis of neurosecretory granules from the dendrites of magnocellular neurons can account for the vasopressin and oxytocin known to be released into the hypothalamus. Exocytosis from cell bodies of magnocellular neurons was not observed in stimulated slices from normal rats but, when granules had been caused to accumulate in the neuronal somata by prior administration of colchicine, exocytosis of granules from the somata was unambiguously identified. These data demonstrate exocytosis from dendrites and cell bodies of a mammalian peptidergic neuron, and show that all parts of their plasmalemma are competent for exocytosis of granules.
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“Subjects with autism spectrum disorder or schizophrenia often do not attend to the appropriate facial cues of others [107, 108].”
From Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior (2009) · cites this paper as [107]
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Cites
Rhodes, C. H., Morriell, J. I., & Pfaff, D. W. (1981) · The Journal of Comparative Neurology · doi:10.1002/cne.901980106 · Cited by 536
WAKERLEY, J. B., & LINCOLN, D. W. (1973) · Journal of Endocrinology · doi:10.1677/joe.0.0570477 · Cited by 327
Moos, F., Freund‐Mercier, M. J., Guerné, Y., Jm, G., Stoeckel, M. E., & Richard, P. (1984) · Journal of Endocrinology · doi:10.1677/joe.0.1020063 · Cited by 269
The Cytoskeleton as a Barrier to Exocytosis in Secretory Cells
Aunis, D., & Bader, M.-F. (1988) · Journal of Experimental Biology · doi:10.1242/jeb.139.1.253 · Cited by 265
DISTRIBUTION OF OXYTOCIN AND VASOPRESSIN IN THE RAT SUPRAOPTIC AND PARAVENTRICULAR NUCLEUS
Swaab, D. F., Nijveldt, F., & Pool, C. W. (1975) · Journal of Endocrinology · doi:10.1677/joe.0.0670461 · Cited by 254
Freund‐Mercier, M. J., & Richard, P. (1984) · The Journal of Physiology · doi:10.1113/jphysiol.1984.sp015302 · Cited by 212
Oxytocin induces morphological plasticity in the adult hypothalamo-neurohypophysial system
Theodosis, D. T., Montagnese, C. M., Rodriguez, F., Vincent, J., & Poulain, D. A. (1986) · Nature · doi:10.1038/322738a0 · Cited by 211
Magnocellular axons in passage through the median eminence release vasopressin
Holmes, M. C., Antoni, F. A., Aguilera, G., & Catt, K. J. (1986) · Nature · doi:10.1038/319326a0 · Cited by 195
Jones, P. M., & Robinson, I. C. A. F. (2008) · Neuroendocrinology · doi:10.1159/000123316 · Cited by 148
Oxytocin-immunoreactive terminals synapse on oxytocin neurones in the supraoptic nucleus
Theodosis, D. T. (1985) · Nature · doi:10.1038/313682a0 · Cited by 141
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Mion, J. (2013) · theses.fr (ABES) · doi:10.70675/91d47531z8447z44d1z9f7ezf39a8e060318
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Metadata
- Authors
- Pow, D. V., & Morris, J. F.
- Affiliations
- University of Oxford (GB)
- Venue
- Neuroscience
- Publisher
- Elsevier BV
- Published
- 1989-01
- Volume
- 32
- Issue
- 2
- Pages
- 435-439
- ISSN
- 0306-4522 (ISSN-L)
- OpenAlex
- W1978044599
- Cited by
- 446
- References
- 30
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 5 · 2023: 10 · 2022: 10 · 2021: 8 · 2020: 13 · 2019: 10 · 2018: 9 · 2017: 10 · 2016: 15 · 2015: 16 · 2014: 12 · 2013: 11 · 2012: 7
- FWCI
- 3.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- exocytosis, dendrites, magnocellular neurons, hypothalamus, neurosecretory granules, vasopressin, oxytocin, neurohypophyseal peptides, tannic acid, colchicine, neuronal somata, peptidergic neurons
- MeSH terms
- Animals, Cytoplasmic Granules, Dendrites, Exocytosis, Male, Oxytocin, Supraoptic Nucleus, Vasopressins, Rats
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