CoChat
Sign Up
Cited by 64Medicinal Plant ResearchPhytochemistry and biological activity of medicinal plantsPhytochemistry Medicinal Plant Applications

The DOI matches its Crossref record.

Chemical and biological analyses of Nigerian Cassia species for laxative activity

Elujoba, A.A., Ajulo, O.O., Iweibo, G.O.·1989·Journal of Pharmaceutical and Biomedical Analysis
DOI 10.1016/0731-7085(89)80150-5
Open this paper in CoChat — free account

Abstract

The leaves of 10 Cassia species (Leguminosae), cultivated in Nigeria, were assayed spectrophotometrically for combined anthraquinone content and also pharmacologically for their laxative properties in male albino rats using official senna leaves (Cassia acutifolia Del.) as the reference standard. Leaves of C. podocarpa Guill, and Perr. and of senna had identical laxative potency. The results of both the chemical and the biological experiments suggested that C. alata L. and C. podocarpa are the most likely candidates for drug development in Nigeria. The use of a laxative index is proposed for the comparative study of Cassia (or any plant species) and its possible application to the quality control of these drugs is discussed.

Overview

Integrity signals

Registry

Crossref · 10.1016/0731-7085(89)80150-5

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 10

  1. Kapadia, 1962, Lloydia, 25, 55
  2. Rai, 1978, Curr. Sci., 47, 271
  3. Rai, 1978, Niger. J. Pharm., 9, 160
  4. Lemli, 1976, Pharmacology, 14, 62, 10.1159/000136686 · DOI
  5. Elujoba, 1988, Planta Med., 54, 372, 10.1055/s-2006-962470 · DOI
  6. Koshioka, 1978, Chem. Pharm. Bull., 26, 1343, 10.1248/cpb.26.1343 · DOI
  7. Latven, 1952, J. Am. Pharm. Assoc., 41, 548, 10.1002/jps.3030411013 · DOI
  8. Lou, 1949, J. Pharm. Pharmac., 1, 673, 10.1111/j.2042-7158.1949.tb12480.x · DOI
  9. Rai, 1978, Curr. Sci., 47, 621
  10. El-Gengaihi, 1975, Planta Med., 27, 349, 10.1055/s-0028-1097813 · DOI

Cited by

Sorted by citations

Metadata

Authors
Elujoba, A. A., Ajulo, O. O., & Iweibo, G. O.
Affiliations
Obafemi Awolowo University (NG)
ORCID
Elujoba, A.A.
Venue
Journal of Pharmaceutical and Biomedical Analysis
Publisher
Elsevier BV
Published
1989-01
Volume
7
Issue
12
Pages
1453-1457
ISSN
0731-7085 (ISSN-L)
DOI
10.1016/0731-7085(89)80150-5
OpenAlex
W1986260383
Cited by
64
References
0
Citations by year
2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 4 · 2015: 5 · 2014: 5 · 2013: 2 · 2012: 2
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Pharmaceutical and Biomedical Analysis (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and biological activity of medicinal plants
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
Keywords
Cassia, laxative activity, Cassia alata, Cassia acutifolia, Senna, medicinal plants
MeSH terms
Animals, Anthraquinones, Cassia, Cathartics, Feces, Male, Nigeria, Plant Extracts, Plants, Medicinal, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review