The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Echocardiographic assessment of patients with infectious endocarditis: Prediction of risk for complications
Open accessAbstract
To enhance the echocardiographic identification of high risk lesions in patients with infectious endocarditis, the medical records and two-dimensional echocardiograms of 204 patients with this condition were analyzed. The occurrence of specific clinical complications was recorded and vegetations were assessed with respect to predetermined morphologic characteristics. The overall complication rates were roughly equivalent for patients with mitral (53%), aortic (62%), tricuspid (77%) and prosthetic valve (61%) vegetations, as well as for those with nonspecific valvular changes but no discrete vegetations (57%), although the distribution of specific complications varied considerably among these groups. There were significantly fewer complications in patients without discernible valvular abnormalities (27%). In native left-sided valve endocarditis, vegetation size, extent, mobility and consistency were all found to be significant univariate predictors of complications. In multivariate analysis, vegetation size, extent and mobility emerged as optimal predictors and an echocardiographic score based on these factors predicted the occurrence of complications with 70% sensitivity and 92% specificity in mitral valve endocarditis and with 76% sensitivity and 62% specificity in aortic valve endocarditis.
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“Several studies with TTE have demonstrated a trend toward higher embolic rates with left-sided vegetations >1 cm in diameter.55”
From Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (2015) · cites this paper as [55]
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“Systemic embolization occurs in 22% to 50% of cases of IE. 55,57,[274][275][276][277]”
From Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (2015) · cites this paper as [55]
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Citations
Cites
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Self-citationInfective endocarditis and echocardiography
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Cited by
Sorted by citations
2015 ESC Guidelines for the management of infective endocarditis
Habib, G., Lancellotti, P., Antunes, M. J., Bongiorni, M. G., Casalta, J., Zotti, F. D., Dulgheru, R., Khoury, G. A. E., Erba, P. A., Iung, B., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv319 · Cited by 5,086
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Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)
Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and by the International Society of Chemotherapy (ISC) for Infection and Cancer, Habib, G., Hoen, B., Tornos, P., Thuny, F., Prendergast, B., Vilacosta, I., Moreillon, P., de Jesus Antunes, M., Thilen, U., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp285 · Cited by 2,014
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ACC/AHA Guidelines for the Clinical Application of Echocardiography
Cheitlin, M. D., Alpert, J. S., Armstrong, W. F., Aurigemma, G. P., Beller, G., Bierman, F. Z., Davidson, T. W., Davis, J. L., Douglas, P. S., Gillam, L. D., et al. (1997) · Circulation · doi:10.1161/01.cir.95.6.1686 · Cited by 844
Metadata
- Authors
- Sanfilippo, A. J., Picard, M. H., Newell, J. B., Rosas, E., Davidoff, R., Thomas, J. D., & Weyman, A. E.
- Affiliations
- Massachusetts General Hospital (US)
- Harvard University (US)
- Corresponding author
- Sanfilippo, Anthony J.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1991-11
- Volume
- 18
- Issue
- 5
- Pages
- 1191-1199
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2091438055
- Semantic Scholar
- 77cbe2ef81fa55b216750cf99958a15b75b73716
- Cited by
- 328
- References
- 23
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 8 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 9 · 2015: 12 · 2014: 9 · 2013: 13 · 2012: 9
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5t32hl007535-08)
- National Heart, Lung, and Blood Institute (HL-07535)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Health Sciences › Medicine › Infectious Diseases › Streptococcal Infections and Treatments
- Keywords
- infective endocarditis, echocardiographic assessment, vegetation characteristics, complication prediction, vegetation size, mitral valve endocarditis, aortic valve endocarditis, tricuspid valve endocarditis, prosthetic valve endocarditis, risk stratification
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Aortic Valve, Echocardiography, Endocarditis, Bacterial, Female, Heart Valve Prosthesis, Humans, Male, Middle Aged, Mitral Valve, Predictive Value of Tests, Regression Analysis, Sensitivity and Specificity, Survival Rate
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