The DOI matches its Crossref record; 23 of the 24 references it cites were found in a registry or an index.
Treatment of complicated prosthetic aortic valve endocarditis with annular abscess formation by homograft aortic root replacement
Open accessAbstract
The outcome of 30 consecutive patients with active aortic prosthetic valve endocarditis and root abscesses treated by the technique of homograft aortic root replacement with reimplantation of the coronary arteries is detailed. The principles of this technique are the removal of all abscesses and infected areas likely to drain into the infected mediastinum, excision of infected tissues down to healthy noninfected tissue and replacement with an antibiotic-impregnated homograft aortic root. All patients had evidence of progressive cardiac failure and ongoing sepsis. Mean patient age (+/- SD) at the time of operation was 42 +/- 18 years. The mean number of previous aortic valve replacements per patient was 1.6 +/- 0.7; 14 patients (47%) had undergone greater than or equal to 2 previous replacements. At operation, aortic root abscesses were found in all patients; abscess extension to adjacent structures and partial valve dehiscence had occurred in 23. In-hospital death occurred in 9 (30%) of the 30 patients. The 21 hospital survivors have been followed up for a mean of 66 +/- 42 months (range 9 to 144). Overall, 17 (81%) of the 21 hospital survivors have remained free of major adverse events (recurrence of endocarditis, need for reoperation or death). The results of our study suggest that homograft aortic root replacement should be considered favorably in the treatment of patients with aortic prosthetic valve endocarditis and root abscesses.
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“Under these conditions, human aortic homografts, when available, can be used to replace the damaged aortic valve and to reconstruct the damaged aorta.310,311”
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Prosthetic valve endocarditis.
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Risk factors for the development of prosthetic valve endocarditis.
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Surgical Management of Left Ventricular–Aortic Discontinuity Complicating Bacterial Endocarditis
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Homograft aortic root replacement for complicated prosthetic valve endocarditis.
Rm, D., & Dm, R. (1984) · PubMed · Cited by 92
Prosthetic valve endocarditis.
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A Practical Approach to Prosthetic Valve Endocarditis
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Early and late results of aortic root replacement with antibiotic-sterilized aortic homograft
Okita, Y., Franciosi, G., Matsuki, O., Robles, A., & Ross, D. N. (1988) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(19)35739-3 · Cited by 76
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ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
2015 ESC Guidelines for the management of infective endocarditis
Habib, G., Lancellotti, P., Antunes, M. J., Bongiorni, M. G., Casalta, J., Zotti, F. D., Dulgheru, R., Khoury, G. A. E., Erba, P. A., Iung, B., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv319 · Cited by 5,086
Baddour, L. M., Wilson, W. R., Bayer, A. S., Fowler, V. G., Tleyjeh, I. M., Rybak, M. J., Barsic, B., Lockhart, P. B., Gewitz, M. H., Levison, M. E., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000296 · Cited by 3,232
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)
Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and by the International Society of Chemotherapy (ISC) for Infection and Cancer, Habib, G., Hoen, B., Tornos, P., Thuny, F., Prendergast, B., Vilacosta, I., Moreillon, P., de Jesus Antunes, M., Thilen, U., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp285 · Cited by 2,014
Metadata
- Authors
- Glazier, J. J., Verwilghen, J., Donaldson, R. M., & Ross, D. N.
- Affiliations
- University College Hospital at Westmoreland Street (GB)
- Corresponding author
- Glazier, James J.
- ORCID
- Glazier, James J.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1991-04
- Volume
- 17
- Issue
- 5
- Pages
- 1177-1182
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2071620212
- Cited by
- 144
- References
- 24
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 5 · 2015: 5 · 2014: 3 · 2013: 4 · 2012: 4
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Surgery › Infectious Aortic and Vascular Conditions
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Keywords
- prosthetic valve endocarditis, aortic valve endocarditis, annular abscess, coronary artery reimplantation, valve dehiscence, recurrent endocarditis, heart failure, sepsis, reoperation
- MeSH terms
- Abscess, Adolescent, Adult, Aged, Aorta, Aortic Valve, Child, Coronary Vessels, Endocarditis, Female, Follow-Up Studies, Haemophilus Infections, Heart Valve Prosthesis, Humans, Male, Middle Aged, Reoperation, Retrospective Studies, Staphylococcal Infections, Transplantation, Homologous, Survival Rate
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