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Assignment of two human α-1,3-galactosyltransferase gene sequences (GGTA1 and GGTA1P) to chromosomes 9q33–q34 and 12q14–q15

Shaper, Nancy L., Lin, Shuan-pei, Joziasse, David H., Kim, DoYoun, Yang-Feng, Teresa L.·1992·Genomics
DOI 10.1016/0888-7543(92)90458-5
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Abstract

alpha-1,3-Galactosyltransferase is a terminal glycosyltransferase that is widely expressed in a variety of mammalian species, with the notable exception of man, apes, and Old World monkeys. Although transcripts for this enzyme are not detectable in humans, homologous sequences have been identified in human genomic DNA. These sequences correspond to a processed pseudogene that maps to chromosome 12 and the inactivated remnant of the once functional source gene that maps to chromosome 9. We have now established that the former sequence (GGTA1P) is localized to 12q14-q15 and the latter sequence (GGTA1) is localized to 9q33-q34 [corrected].

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Research works printed but not linked: 15

  1. Blanken, 1985, Biosynthesis of terminal Gal1,3Galβ1,4GlcNAc-R oligosaccharide sequences on glycoconjugates, J. Biol. Chem, 260, 12927, 10.1016/S0021-9258(17)38814-2 · DOI
  2. Cook, 1978, Segregation of ABO, AK1 and ACON in families with abnormalities of chromosome 9, Ann. Hum. Genet, 41, 365, 10.1111/j.1469-1809.1978.tb01904.x · DOI
  3. Cummings, 1988, Retinoic-acid induced differentiation of mouse teratocarcinoma cell line F9 is accompanied by an increase in the activity of UDP-Gal:β-d-galactosyl α1,3-galactosyltransferase, J. Biol. Chem, 263, 511, 10.1016/S0021-9258(19)57422-1 · DOI
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Metadata

Authors
Shaper, N. L., Lin, S.-P., Joziasse, D. H., Kim, D., & Yang-Feng, T. L.
Venue
Genomics
Publisher
Elsevier BV
Published
1992-03
Volume
12
Issue
3
Pages
613-615
ISSN
0888-7543
DOI
10.1016/0888-7543(92)90458-5
Cited by
37
References
0
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Assignment of two human α-1,3-galactosyltransferase gene sequences (GGTA1 and GGTA1P) to chromosomes 9q33–q34 and 12q14–q15. https://app.cochat.ai/papers/10.1016/0888-7543(92)90458-5
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Shaper, N. L., Lin, S.-P., Joziasse, D. H., Kim, D., & Yang-Feng, T. L. (1992). Assignment of two human α-1,3-galactosyltransferase gene sequences (GGTA1 and GGTA1P) to chromosomes 9q33–q34 and 12q14–q15. Genomics. https://doi.org/10.1016/0888-7543(92)90458-5