The DOI matches its Crossref record; 351 of the 351 references it cites were found in a registry or an index.
Covalent Modification of DNA by Natural Products
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“Under the conditions of disturbed redox metal homeostasis (e.g. Alzheimer’s diseases and some cancers), free (unbound) metal ions can catalyze heterolytic cleavage of hydrogen peroxide (formed by the SOD-catalyzed dismutation reaction), resulting in the formation of hydroxyl radicals (·OH) and OH−. This reaction is termed the Fenton reaction (Valko et al. 2005; Gates 1999)7”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Gates 1999
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Metadata
- Authors
- Gates, K. S.
- Affiliations
- University of Missouri (US)
- Corresponding author
- Gates, Kent S.
- ORCID
- Gates, Kent S.
- Venue
- Comprehensive Natural Products Chemistry
- Publisher
- Elsevier
- Published
- 1999
- Pages
- 491-552
- OpenAlex
- W2951334876
- Cited by
- 44
- References
- 351
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2017: 1 · 2015: 3 · 2014: 1 · 2012: 1
- FWCI
- 1.56
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Elsevier eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Bioactive Compounds and Antitumor Agents
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Keywords
- natural products, DNA adducts, DNA damage, genotoxicity
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