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Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio)

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Kossack, Michelle E., Draper, Bruce W.·2019·Current Topics in Developmental Biology

Abstract

Over the last several decades zebrafish (Danio rerio) has become a major model organism for the study of vertebrate development and physiology. Given this, it may be surprising how little is known about the mechanism that zebrafish use to determine sex. While zebrafish are a gonochoristic species (having two sexes) that do not switch sex as adults, it was appreciated early on that sex ratios obtained from breeding lab domesticated lines were not typically a 1:1 ratio of male and female, suggesting that sex was not determined by a strict chromosomal mechanism. Here we will review the recent progress toward defining the genetic mechanism for sex determination in both wild and domesticated zebrafish.

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Metadata

Authors
Kossack, M. E., & Draper, B. W.
Venue
Current Topics in Developmental Biology
Publisher
Elsevier
Published
2019
Volume
134
Pages
119-149
ISSN
0070-2153 (ISSN-L)
OpenAlex
W2922730069
Cited by
159
References
2
FWCI
41.77
Type
book chapter
Language
en
Open access
green

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CoChat. (2026). Citation check: Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio). https://app.cochat.ai/papers/10.1016/bs.ctdb.2019.02.004
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Kossack, M. E., & Draper, B. W. (2019). Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio). Current Topics in Developmental Biology. https://doi.org/10.1016/bs.ctdb.2019.02.004

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