Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors
Ojha, Tarun, Pathak, Vertika, Shi, Yang, Hennink, Wim E., Moonen, Chrit T.W., Storm, Gert, Kiessling, Fabian, Lammers, Twan·2017·Advanced Drug Delivery Reviews
Cited by (260)
Items 201–260 of 260
- Progress and Hurdles of Therapeutic Nanosystems against CancerMarina Martín-Contreras, Saúl A. Navarro-Marchal, José Manuel Peula-García, Ana Belén Jódar‐Reyes · 2022 · Pharmaceutics
- Awakening Allies for Breaking Microenvironment Barriers: NIR‐II Guided Orthogonal Activation of Tumor‐Infiltrating Mast Cells for Efficient Nano‐Drug DeliveryQingyuan Wang, Haiyan Yang, Yuan Liu, Zhaoxi Zhou, Xu Zhang, Ming‐Yi Sang, Feng Xu, Lebin Song, Tiansong Xia, Yue Zhang et al. · 2023 · Advanced Healthcare Materials
- Nanohybrid cerasomes: Advancements in targeted drug and gene deliveryKalyani Pathak, Mohammad Zaki Ahmad, Riya Saikia, Partha Protim Borthakur, Pallab Pramanik, Md Ariful Islam, Aparoop Das, Basel A. Abdel‐Wahab, Dibyajyoti Das, Saptasikha Gogoi · 2024 · European Journal of Medicinal Chemistry Reports
- Evaluation of release and pharmacokinetics of hexadecylphosphocholine (miltefosine) in phosphatidyldiglycerol-based thermosensitive liposomesAlexander Rysin, Michael Paal, Wouter J.M. Lokerse, Barbara Wedmann, Martin Hossann, Michael Vogeser, Gerhard Winter, Lars Hartwin Lindner · 2021 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- Enzyme-Loaded Catalytic Macrophage Vesicles with Cascade Amplification of Tumor-Targeting for Oxygenated Photodynamic TherapyLing Liu, Jiayu Zhang, Zinan Li, Yang Yang, Longyun Li, Yuyang Zhao, Jia Zhao · 2021 · International Journal of Nanomedicine
- Riboflavin-targeted polymers improve tolerance of paclitaxel while maintaining therapeutic efficacyMilita Darguzyte, Elena Rama, Anne Rix, Jasmin Baier, Juliane Hermann, Sima Rezvantalab, Mohammad Khedri, Joachim Jankowski, Fabian M. Kiessling · 2024 · Nanomedicine Nanotechnology Biology and Medicine
- Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and MicroenvironmentAnne-Kathrin Noack, Henrike Lucas, Petr Chytil, Tomáš Etrych, Karsten Mäder, Thomas Mueller · 2020 · International Journal of Molecular Sciences
- Protein Corona Attenuates the Targeting of Antitumor Sialyl Lewis X-Decorated Liposomes to Vascular Endothelial Cells under Flow ConditionsNatalia R. Onishchenko, Алексей Александрович Московцев, Maria K. Kobanenko, Daria S. Tretiakova, Anna S. Alekseeva, D V Kolesov, А.А. Микрюкова, Ivan A. Boldyrev, Капкаева Марина Рафаилевна, О. Н. Щегловитова et al. · 2023 · Pharmaceutics
- Polymeric micelles in advanced photodynamic therapy: Design, delivery and translational prospectsAlžběta Turnovská, Tomáš Etrych · 2025 · International Journal of Pharmaceutics X
- The histone-modified landscape: Core mechanisms of osimertinib resistance in EGFR-mutant lung cancerJie Yang, Minpu Zhang, Chundi Gao, Xiaoyu Yao, Changgang Sun, Jing Zhuang · 2026 · Cancer Letters
- Recent Advances of Poly(lactic‐co‐glycolic acid)‐Based Nanoparticles for Tumor‐Targeted Drug DeliveryLinye Jiang, Jie Luo, Dawei Hong, Shuhong Guo, Shuyi Wang, Bizhong Zhou, Shiyu Zhou, Jingyan Ge · 2022 · ChemistrySelect
- Modern trends of using innovative nanoparticle approaches for immune-based osteosarcoma therapySana Kausar, Hussain Raza, Young Seok Eom, Abdul Samad, Song Ja Kim · 2025 · International Immunopharmacology
- Indocyanine Green-Loaded Liposomes-Assisted Photoacoustic Computed Tomography for Evaluating In Vivo Tumor Penetration of Liposomal NanocarriersChenjun Wu, Qi Sun, Xiangdong Liu, Xin Shun Sun, Zeyu Chen, Shan Han · 2023 · Micromachines
- Desmoplastic tumor priming using clinical-stage corticosteroid liposomesTarun Ojha, Gideon J L Schaefer, Rahaf Mihyar, Vertika Pathak, Josef Ehling, Elena Rama, Federica De Lorenzi, Asmaa Said Elshafei, Diana Moeckel, Sara Elsafy et al. · 2025 · Cell Biomaterials
- [Construction and Anti-tumor Effect Evaluation of a Dual-Responsive Hyaluronic Acid Carbon Quantum Dot-Gelatin Nano-Drug Delivery System].Man Li, Jian-Ping Li, Ya-Shi Wang, Qin He · 2021 · PubMed Central
- Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor‐Targeted Drug DeliveryIlaria Biancacci, Daniele De Santis, Elena Rama, Karina Benderski, Jeffrey Momoh, Robert F. Pohlberger, Diana Moeckel, Leonard Kaps, Cristianne J.F. Rijcken, Jai Prakash et al. · 2023 · Advanced Therapeutics
- Curcumin nanocrystallites are an ideal nanoplatform for cancer chemotherapyXiaojun Wang, Yaonan Peng, Huı Tan, Weiping Li, Mingtao Li · 2019 · Frontiers in Nanoscience and Nanotechnology
- Shield-activated two-way imaging nanomaterials for enhanced cancer theranosticsYang Xu, Zhaokun Nie, Nengyi Ni, Xinyu Zhang, Jia Yu Yuan, Yuan Gao, Yufang Gong, Shuangqing Liu, Min Cong Wu, Xiao Jun Sun · 2022 · Biomaterials Science
- Mesoporous polydopamine nanoparticles coated with metal-polyphenol networks for demethylation therapy of lung cancerJingsi Wang, Xufeng Deng, Manyuan Li, Xiaobing Liu, Quanxing Liu · 2025 · Medical Oncology
- Macro-, micro- and nanoscale drug delivery systems in oncotherapy: current clinical statusPaul Adrian Tărăbuță · 2025 · Biomaterials Advances
- Polymeric micellar nanomedicine for enhanced permeability and retention effect–based tumor-targeted deliveryRayhanul Islam, Jun Qun Fang · 2022 · Elsevier eBooks
- Vascular normalization with pegylated emulsion of SU5416 enhances anti-tumor effect of liposomal paclitaxel in 4T1 breast cancer-bearing mice: Analysis of intratumoral vessels and microenvironmentMasato Maruyama, Hazuki Matsui, Haruka Nakamura, Reiya Torii, Yuta Takasugi, Ken‐ichi Ogawara, Kazutaka Higaki · 2024 · Journal of Drug Delivery Science and Technology
- Navigating the nanoscale: Principles of body navigationSaed Abbasi, Anjaneyulu Dirisala, Daniel Gonzalez‐Carter, West Kristian D. Paraiso, Junjie Li, Theofilus A. Tockary · 2024 · Elsevier eBooks
- Polymer-Based Tumor-targeted NanosystemsTeoman Benli‐Hoppe, Ernst Wagner · 2020 · Springer eBooks
- Recent Advances in Polymer‐Modified Liposomes for Cancer TreatmentSwapnil K. Sharma, Akansha Bisht, Sanjana Tewari, Vivek Dave · 2021
- Assessing Tumor Microenvironment Characteristics and Stratifying EPR with a Nanobubble Companion Nanoparticle via Contrast-Enhanced Ultrasound ImagingMichaela B. Cooley, Dana Wegierak, Reshani Perera, Eric Abenojar, Pinunta Nittayacharn, Felipe M. Berg, Youjoung Kim, Michael C. Kolios, Agata A. Exner · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Effect of Ultrasound Combined with Microbubbles on Blood Perfusion in Invasive Breast Cancer—A Prospective Clinical TrialYunyun Dong, Daqing Zhang, Wei Feng, Yuqing Huang, Zhicheng Ge, Xiaoyi Shi · 2026 · Technology in Cancer Research & Treatment
- Sonodynamic Therapy-Enhanced Immunotherapy for Triple-Negative Breast Cancer: Mechanistic Advances, Nanoplatform Strategies, and Clinical ProspectsRamanjireddy Tatiparthi, Ansuman Panda, MVNL Chaitanya, Fanta Gashe, Gemmechu Hasan, Raghavendra Yarlagadda · 2026 · Molecular Imaging and Biology
- Advances in Hyperthermic Intraperitoneal Chemotherapy达 练 · 2026 · Advances in Clinical Medicine
- Cubosomes in Anticancer Drug Delivery: Structural Insights, Formulation Strategies, and Translational PerspectivesJayvadan Patel, Aryan Patel, Rajesh K.S., Gajanan Shinde, Sai Patel, Gaurav Patil, Chanakshi Pawar, Sanjay A. Nagdev, Prashant Bhagwan Patil · 2026 · ChemistrySelect
- Integrating tumor microenvironment modulation with nanocarrier engineering for enhanced tumor-targeted deliveryThu A. Hoang, Eunhee Lee, Duhyeong Hwang, Hyuk Jun Cho, Soyeun Park · 2026 · Journal of Controlled Release
- Effect of an Endothelin B Receptor Agonist on the Tumor Accumulation of NanocarriersHaitao Feng, Le Thanh Nam, Takuma Yoshikawa, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama · 2020 · Biological and Pharmaceutical Bulletin
- Advanced drug delivery systems in kidney cancerNimisha, Apoorva Singh, Kalpana Pandey · 2021 · Elsevier eBooks
- Cancer Stem Cell Therapeutic Delivery and EPR EffectRayhanul Islam, Jun Qun Fang · 2023 · Springer eBooks
- Synergic fabrication of arsenic and anticancer drug-loaded ZIF-8 nanocomposites for improved radiofrequency ablation of liver metastasis cancer therapyDongwen Rong, Junmei Jia, Haile Qiu, Yanyan Liu, Chenan Liu, Xiaoyuan Wei · 2023 · Materials Technology
- Cd44 Targeted Plga Nano-Medicine For Cancer Chemotherapy- A Comprehensive ReviewRavi Kumar, Sunıta JHA, Awanish Rai · 2023 · Journal of Immunology and Clinical Microbiology
- Pet Imaging Of Early Therapeutic Response In Solid TumorsStephanie J. Blocker · 2017 · Human Biology
- Peer Review #4 of "The effect of cycling hypoxia on MCF-7 cancer stem cells and the impact of their microenvironment on angiogenesis using human umbilical vein endothelial cells (HUVECs) as a model (v0.1)"2019 · PeerJ
- Tumor-Responsive Drug Release StrategiesZhaoqing Shi, Yun Zhou, Lin Mei · 2020 · Springer eBooks
- Strategies for targeted and image-guided drug delivery to tumorAyele H. Negussie · 2021
- Transcytosis-inducing biomaterials for actively translocating nanomedicinesLei Xu, Quan Zhou, Shiqun Shao, Youqing Shen · 2021 · Elsevier eBooks
- Peer Review #2 of "The effect of cycling hypoxia on MCF-7 cancer stem cells and the impact of their microenvironment on angiogenesis using human umbilical vein endothelial cells (HUVECs) as a model (v0.2)"2019 · PeerJ
- Peer Review #1 of "The effect of cycling hypoxia on MCF-7 cancer stem cells and the impact of their microenvironment on angiogenesis using human umbilical vein endothelial cells (HUVECs) as a model (v0.2)"2019 · PeerJ
- Methods for Analysis of Extracellular Vesicle FunctionsShijing Yue, Haobin Wang, Kun Zhao, Wei Mu, Zhe Wang · 2024 · Springer eBooks
- Nanoimaging in Cancer Part ISikandar Shaikh · 2024 · Springer eBooks
- Low‐Dose X‐Ray Radiation Enhances Intratumoral Accumulation and Antitumor Effects of Nanoscale Coordination Polymers via Neutrophil‐Mediated TraffickingLangston Tillman, Xiaomin Jiang, Chaoyu Wang, Yuxuan Xiong, Wenbin Lin · 2025 · Advanced NanoBiomed Research
- Advancing tumor immunotherapy through rationally engineered inorganic nanomaterialsYiwei Li, Pengchao Zhang, Yumei Xiao, Xingdong Zhang, Qin Zeng, Xiangdong Zhu · 2025 · Acta Biomaterialia
- Additional file 1 of Rationally assembled albumin/indocyanine green nanocomplex for enhanced tumor imaging to guide photothermal therapyAn, Feifei, Yang, Zhao, Meichen Zheng, Mei, Ting, Deng, Guowei, Guo, Ping, Li, Yanan, Ruilong Sheng · 2020 · Figshare
- DNA as Drug Carrier: A Hydrophobic β‐Cyclodextrin Channel in a Supramolecular StructureGiuseppina Raffaini · 2026 · Chemistry - A European Journal
- Tumor responsive nanoplatforms for TME modulation: From extracellular matrix to intracellular organellesHao Shu, Chin Siew Sia, Shirley Soon Lee Tiang, Bey-Hing Goh, Yiin Jian Low, Beng Ti Tey, Liang Ee Low · 2026 · Journal of Drug Delivery Science and Technology
- Réponses cellulaires et tissulaires de la peau humaine à l'application d'un champ électrique externe de type électroporationSara Gouardères · 2021 · theses.fr (ABES)
- Surface engineered hybrid nanocarriers for cancer treatmentAngelika Mielcarek · 2020 · theses.fr (ABES)
- Drug Delivery Engineering Strategies Targeting CD4+/CD8+ T Cell Exhaustion to Improve the Tumor Immunosuppressive MicroenvironmentJingsi Yue, Min Chen, Zuanyu Xiong, Jing Qiu, Yi Liu, Long Chen · 2026 · International Journal of Nanomedicine
- Progressive insights into nanomaterials for cancer starvation therapyJianbin Shi, Jidan Cui, Xinxin Sun, Jin Sun, Zhonggui He, Cong Luo, Shenwu Zhang · 2026 · Science China Materials
- Safety, pharmacokinetics, pharmacodynamics and antitumor activity of legubicin in patients with advanced solid tumors, including lung cancer: a phase 1 dose-escalation and expansion trialFengjuan Lin, Junli Xue, Qun Li, Wenbo Tang, Wei Zhao, Liqiong Xue, Jiuli Zhou, Yuan Liu, Wenyue Jin, Hui Sun et al. · 2026 · BMC Cancer
- Chemical Ingredients and Antitumor Application of Dragon’s BloodS J Zhang, Shiyu Zhu, Xinchen Liu, Dongyang Zhou, Xiusong Tang, Dongjie Zhang, Jing Wang, Yan Wei, Hongbo Li · 2026 · Natural Product Communications
- Drug repurposing: Losartan reverses cancer drug resistance via microenvironment reprogrammingBixian Han, Yiming Xu, Ryan Li, Pei-Gen Huang, Zhe‐Sheng Chen, Mingzhu Xiao · 2026 · Genes & Diseases
- Loureirin A, derived from Dragon's blood, promoted drug delivery and efficacy in pancreatic cancer via vascular promotionJing Wang, Xinchen Liu, Xiusong Tang, Songyan Gao, Shudong Zhang, Yan Wei, Hongbo Li · 2026 · Biochemical and Biophysical Research Communications
- Green Synthesis and Functional Design of Polypyrrole-Based Nanomedicines for Cancer Theranostics: A Critical Review and Sustainability-Guided PerspectiveJiaqiao Zhong, Yuanzhe Li · 2026 · Polymers
- Resiquimod Improves the Tumor Accumulation and Antitumor Activity of SN38 Prodrug-Loaded LiposomesTao Yang, Hongling Xu, Cheng Li, Manlin Wang, Xin Zeng, Yongjian Huang, Hongying Abamo, Qiong Man, Yaxin Zheng, Yang Li · 2026 · Molecular Pharmaceutics