Impact of GLP-1 Agonists and SGLT-2 Inhibitors on Diabetic Retinopathy Progression: An Aggregated Electronic Health Record Data Study

Wai, Karen M.; Mishra, Kapil; Koo, Euna; Ludwig, Cassie Ann; Parikh, Ravi; Mruthyunjaya, Prithvi; Rahimy, Ehsan

doi:10.1016/j.ajo.2024.04.010

Impact of GLP-1 Agonists and SGLT-2 Inhibitors on Diabetic Retinopathy Progression: An Aggregated Electronic Health Record Data Study

Purpose: To examine the effects of GLP-1 agonists compared to SGLT-2 inhibitors on diabetic retinopathy. Design: Retrospective clinical cohort study using TriNetX (Cambridge, MA, USA), a federated electronic health records network comprising multiple healthcare organizations. Methods: Patients wi…