Reoperation 10 years after surgically managed pelvic organ prolapse and urinary incontinence
Abstract
Objective This study measured the 10-year risk of reoperation for surgically treated pelvic organ prolapse and urinary incontinence (POPUI) in a community population.Study design We conducted a prospective cohort analysis of 374 women who were > 20 years old and who underwent surgery for POPUI in 1995.Results The 10-year reoperation rate was 17% by Kaplan Meier analysis. Previous POPUI surgery at the time of index surgery conferred a hazard ratio of 1.9 (95% CI, 1.1-3.2; P = .018). The abdominal approach was protective against reoperation compared with the vaginal approach (hazard ratio, 0.37; 95% CI, 0.17-0.83; P = .02) With the use of Cox regression, no association was observed for age, vaginal parity, previous hysterectomy, body mass index, prolapse severity, ethnicity, chronic lung disease, smoking, estrogen status, surgical indication, or anatomic compartment.Conclusion A reoperation rate of 17% is unacceptably high and likely represents an underestimate of the true rate. Most of the factors that influence reoperation have not yet been identified.
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Recurrence at the same site may be because the primary surgery did not address the underlying neuromuscular and connective tissue dysfunction responsible for the primary prolapse.
“The recurrence at the same site may be because the primary surgery to correct the anatomical defect may not have taken care of the underlying neuromuscular and connective tissue dysfunction that was responsible for the primary prolapse and this could have played a significant role in the recurrence [8, 28].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [8]
The lifetime risk of undergoing surgery to correct POP is 11.9%.
“The lifetime risk of undergoing surgery to correct POP is 11.9% [7, 8] and close to 200,000 women undergo surgery for POP in the USA annually [9, 10].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [8]
Our data is consistent with previous studies reporting reoperation rates ranging from 10-19% with varying follow-up time between 5-32 years.
“Our data is consistent with previous studies reporting reoperation rates ranging from 10–19% [ 15 , 19 – 23 ] with varying follow-up time between 5–32 years.”
From Recurrent pelvic organ prolapse after hysterectomy; a 10-year national follow-up study (2024) · cites this paper as [23]
In women without pre-existing POP, rectocele is the most common POP following hysterectomy.
“Although the number of women requiring reoperation for posterior POP is relatively low, it is noteworthy that in women without pre-existing POP, rectocele is the most common POP following hysterectomy [ 9 , 17 , 22 , 23 ].”
From Recurrent pelvic organ prolapse after hysterectomy; a 10-year national follow-up study (2024) · cites this paper as [23]
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References 17 · Cited by 180
- Authors
- Denman, M. A., Gregory, W. T., Boyles, S. H., Smith, V., Edwards, S. R., & Clark, A. L.
- Affiliations
- Oregon Health & Science University (US)
- Providence Portland Medical Center (US)
- Kaiser Permanente (US)
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2008-05
- Volume
- 198
- Issue
- 5
- Pages
- 555.e1-555.e5
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2025804200
- Cited by
- 180
- References
- 17
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 9 · 2023: 13 · 2022: 13 · 2021: 14 · 2020: 8 · 2019: 12 · 2018: 12 · 2017: 12 · 2016: 14 · 2015: 10 · 2014: 9 · 2013: 11 · 2012: 12
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Ureteral procedures and complications
- Keywords
- pelvic organ prolapse, urinary incontinence, reoperation, long-term surgical outcomes, risk factors for reoperation, women's health
- MeSH terms
- Adult, Aged, Female, Humans, Middle Aged, Recurrence, Reoperation, Risk Factors, Gynecologic Surgical Procedures, Urinary Incontinence, Uterine Prolapse
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