Obstructive sleep apnea and the risk of adverse pregnancy outcomes
Abstract
Objective We examined the risk of adverse pregnancy outcomes, including low birthweight (LBW), preterm birth, small for gestational age (SGA), cesarean section (CS), low Apgar score (at 5 minutes after delivery), and preeclampsia in pregnant women with and without obstructive sleep apnea (OSA).Study design Our subjects included 791 women with OSA and 3955 randomly selected women without OSA. We performed conditional logistic regression analyses to examine the risks of adverse pregnancy outcomes between women with and without OSA.Results Compared with women without OSA, adjusted odds ratios for LBW, preterm birth, SGA infants, CS, and preeclampsia in women with OSA were 1.76 (95% confidence interval [CI], 1.28-2.40), 2.31 (95% CI, 1.77-3.01), 1.34 (95% CI, 1.09-1.66), 1.74 (95% CI, 1.48-2.04), and 1.60 (95% CI, 2.16-11.26), respectively.Conclusion Pregnant women with OSA are at increased risk for having LBW, preterm, and SGA infants, CS, and preeclampsia, compared with pregnant women without OSA.
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Sleep disturbance in pregnant women can result in adverse outcomes for both the mother and the fetus.
“Sleep disturbance in pregnant women can result in adverse outcomes for both the mother and the fetus.156,157”
From Sleep, Health, and Society (2017) · cites this paper as [156]
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References 28 · Cited by 246
- Authors
- Chen, Y.-H., Kang, J.-H., Lin, C.-C., Wang, I.-T., Keller, J. J., & Lin, H.-C.
- Affiliations
- Taipei Medical University (TW)
- Taipei Medical University Hospital (TW)
- Corresponding author
- Lin, Herng-Ching
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2012-02
- Volume
- 206
- Issue
- 2
- Pages
- 136.e1-136.e5
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W1990896000
- Cited by
- 246
- References
- 28
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 10 · 2023: 13 · 2022: 15 · 2021: 19 · 2020: 21 · 2019: 12 · 2018: 23 · 2017: 24 · 2016: 21 · 2015: 18 · 2014: 17 · 2013: 26 · 2012: 6
- FWCI
- 10.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- obstructive sleep apnea, pregnancy, adverse pregnancy outcomes, low birth weight, preterm birth, small for gestational age, cesarean section, preeclampsia, Apgar score
- MeSH terms
- Adolescent, Adult, Cross-Sectional Studies, Female, Humans, Infant, Low Birth Weight, Infant, Newborn, Middle Aged, Pre-Eclampsia, Pregnancy, Pregnancy Outcome, Risk, Databases, Factual, Sleep Apnea, Obstructive, Premature Birth
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