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Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer
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Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20107 · Cited by 54,679
Global Cancer Statistics, 2002
Parkin, D. M., Bray, F., Ferlay, J., & Pisani, P. (2005) · CA: A Cancer Journal for Clinicians · doi:10.3322/canjclin.55.2.74 · Cited by 18,196
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., et al. (1997) · Science · doi:10.1126/science.275.5308.1943 · Cited by 4,785
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
Stambolic, V., Suzuki, A., de la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P., & Mak, T. W. (1998) · Cell · doi:10.1016/s0092-8674(00)81780-8 · Cited by 2,551
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
Chen, Z., Trotman, L. C., Shaffer, D., Lin, H.-K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., et al. (2005) · Nature · doi:10.1038/nature03918 · Cited by 1,993
Pten is essential for embryonic development and tumour suppression
Cristofano, A. D., Pesce, B., Cordon-Cardo, C., & Pandolfi, P. P. (1998) · Nature Genetics · doi:10.1038/1235 · Cited by 1,516
Wang, S., Gao, J., Lei, Q., Rozengurt, N., Pritchard, C., Jiao, J., Thomas, G. V., Li, G., Roy-Burman, P., Nelson, P. S., et al. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00215-0 · Cited by 1,109
Essential role for nuclear PTEN in maintaining chromosomal integrity
Shen, W. H., Balajee, A. S., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., & Yin, Y. (2007) · Cell · doi:10.1016/j.cell.2006.11.042 · Cited by 979
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
Podsypanina, K., Ellenson, L. H., Nemes, A., Gu, J., Tamura, M., Yamada, K. M., Cordon-Cardo, C., Catoretti, G., Fisher, P. E., & Parsons, R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1563 · Cited by 946
The PTEN/PI3K/AKT Signalling Pathway in Cancer, Therapeutic Implications
Carnero, A., Blanco-Aparicio, C., Renner, O., Link, W., & Leal, J. (2008) · Current Cancer Drug Targets · doi:10.2174/156800908784293659 · Cited by 887
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
Tomlins, S. A., Laxman, B., Dhanasekaran, S. M., Helgeson, B. E., Cao, X., Morris, D. S., Menon, A., Jing, X., Cao, Q., Han, B., et al. (2007) · Nature · doi:10.1038/nature06024 · Cited by 844
Ehrich, M., Nelson, M. R., Stanssens, P., Zabeau, M., Liloglou, T., Xinarianos, G., Cantor, C. R., Field, J. K., & van den Boom, D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507816102 · Cited by 812
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., & Tonks, N. K. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9052 · Cited by 775
Ubiquitination regulates PTEN nuclear import and tumor suppression
Trotman, L. C., Wang, X., Alimonti, A., Chen, Z., Teruya-Feldstein, J., Yang, H., Pavletich, N. P., Carver, B. S., Cordon-Cardo, C., Erdjument-Bromage, H., et al. (2007) · Cell · doi:10.1016/j.cell.2006.11.040 · Cited by 748
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
Cairns, P., Okami, K., Halachmi, S., Halachmi, N., Esteller, M., Herman, J. G., Jen, J., Isaacs, W. B., Bova, G. S., & Sidransky, D. (1997) · PubMed · Cited by 700
Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
Tomlins, S. A., Laxman, B., Varambally, S., Cao, X., Yu, J., Helgeson, B. E., Cao, Q., Prensner, J. R., Rubin, M. A., Shah, R. B., et al. (2008) · Neoplasia · doi:10.1593/neo.07822 · Cited by 690
Pten Dose Dictates Cancer Progression in the Prostate
Trotman, L. C., Niki, M., Dotan, Z. A., Koutcher, J. A., Di Cristofano, A., Xiao, A., Khoo, A. S., Roy-Burman, P., Greenberg, N. M., Dyke, T. V., et al. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000059 · Cited by 676
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
Carver, B. S., Tran, J., Gopalan, A., Chen, Z., Shaikh, S., Carracedo, A., Alimonti, A., Nardella, C., Varmeh, S., Scardino, P. T., et al. (2009) · Nature Genetics · doi:10.1038/ng.370 · Cited by 659
McMenamin, M. E., Soung, P., Perera, S., Kaplan, I. D., Loda, M. F., & Sellers, W. R. (1999) · PubMed · Cited by 640
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
Di Cristofano, A., De Acetis, M., Koff, A., Cordon-Cardo, C., & P Pandolfi, P. (2001) · Nature Genetics · doi:10.1038/84879 · Cited by 498
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
King, J. C., Xu, J., Wongvipat, J., Hieronymus, H., Carver, B. S., Leung, D. H., Taylor, B. S., Sander, C., Cardiff, R. D., Couto, S. S., et al. (2009) · Nature Genetics · doi:10.1038/ng.371 · Cited by 477
Suzuki, H., Freije, D., Nusskern, D. R., Okami, K., Cairns, P., Sidransky, D., Isaacs, W. B., & Bova, G. S. (1998) · PubMed · Cited by 452
Lotan, T. L., Gurel, B., Sutcliffe, S., Esopi, D., Liu, W., Xu, J., Hicks, J. L., Park, B. H., Humphreys, E., Partin, A. W., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-1244 · Cited by 348
Akt-regulated pathways in prostate cancer
Majumder, P. K., & Sellers, W. R. (2005) · Oncogene · doi:10.1038/sj.onc.1209096 · Cited by 344
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
Kwabi-Addo, B., Giri, D., Schmidt, K., Podsypanina, K., Parsons, R., Greenberg, N., & Ittmann, M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201167798 · Cited by 323
Small Subgroup of Aggressive, Highly Proliferative Prostatic Carcinomas Defined by p53 Accumulation
Visakorpi, T., Kallioniemi, O.-P., Heikkinen, A., Koivula, T., & Isola, J. (1992) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/84.11.883 · Cited by 304
Yoshimoto, M., Cunha, I. W., Coudry, R. A., Fonseca, F. P., Torres, C. H., Soares, F. A., & Squire, J. A. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6603924 · Cited by 295
Yoshimoto, M., Joshua, A. M., Cunha, I. W., Coudry, R. A., Fonseca, F. P., Ludkovski, O., Zielenska, M., Soares, F. A., & Squire, J. A. (2008) · Modern Pathology · doi:10.1038/modpathol.2008.96 · Cited by 279
on behalf of the Transatlantic Prostate Group, Reid, A. H. M., Attard, G., Ambroisine, L., Fisher, G., Kovacs, G., Brewer, D., Clark, J., Flohr, P., Edwards, S., et al. (2010) · British Journal of Cancer · doi:10.1038/sj.bjc.6605554 · Cited by 250
Minner, S., Enodien, M., Sirma, H., Luebke, A. M., Krohn, A., Mayer, P. S., Simon, R., Tennstedt, P., Müller, J., Scholz, L., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-1251 · Cited by 249
Self-citationHan, B., Mehra, R., Lonigro, R. J., Wang, L., Suleman, K., Menon, A., Palanisamy, N., Tomlins, S. A., Chinnaiyan, A. M., & Shah, R. B. (2009) · Modern Pathology · doi:10.1038/modpathol.2009.69 · Cited by 227
Sircar, K., Yoshimoto, M., Monzon, F. A., Koumakpayi, I. H., Katz, R. L., Khanna, A., Alvarez, K., Chen, G., Darnel, A. D., Aprikian, A. G., et al. (2009) · The Journal of Pathology · doi:10.1002/path.2559 · Cited by 208
Self-citationZong, Y., Xin, L., Goldstein, A. S., Lawson, D. A., Teitell, M. A., & Witte, O. N. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905931106 · Cited by 203
Clinical significance of p53 alterations in surgically treated prostate cancers
Schlomm, T., Iwers, L., Kirstein, P., Jessen, B., Köllermann, J., Minner, S., Passow-Drolet, A., Mirlacher, M., Milde-Langosch, K., Graefen, M., et al. (2008) · Modern Pathology · doi:10.1038/modpathol.2008.104 · Cited by 196
Self-citationYoshimoto, M., Cutz, J.-C., Nuin, P. A. S., Joshua, A. M., Bayani, J., Evans, A. J., Zielenska, M., & Squire, J. A. (2006) · Cancer Genetics and Cytogenetics · doi:10.1016/j.cancergencyto.2006.04.003 · Cited by 181
Expression patterns of potential therapeutic targets in prostate cancer
Zellweger, T., Ninck, C., Bloch, M., Mirlacher, M., Koivisto, P. A., Helin, H. J., Mihatsch, M. J., Gasser, T. C., & Bubendorf, L. (2005) · International Journal of Cancer · doi:10.1002/ijc.20615 · Cited by 165
Bedolla, R. G., Prihoda, T. J., Kreisberg, J. I., Malik, S. N., Krishnegowda, N. K., Troyer, D. A., & Ghosh, P. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-0091 · Cited by 149
Gammal, A. E. E., Brüchmann, M., Zustin, J., Isbarn, H., Hellwinkel, O., Köllermann, J., Sauter, G., Simon, R., Wilczak, W., Schwarz, J., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-1423 · Cited by 146
Self-citationMinner, S. J. P., Jessen, B., Stiedenroth, L., Burandt, E., Köllermann, J. W., Mirlacher, M., Erbersdobler, A., Eichelberg, C., Fisch, M., Brümmendorf, T. H., et al. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-2546 · Cited by 144
Self-citationIs PTEN loss associated with clinical outcome measures in human prostate cancer?
McCall, P. J., Witton, C. J., Grimsley, S. J. S., et al. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604680 · Cited by 135
Haplo‐insufficiency: a driving force in cancer
Berger, A. H., & Pandolfi, P. P. (2010) · The Journal of Pathology · doi:10.1002/path.2800 · Cited by 131
PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer
Bismar, T. A., Yoshimoto, M., Vollmer, R. T., Duan, Q., Firszt, M., Corcos, J., & Squire, J. A. (2010) · British Journal of Urology · doi:10.1111/j.1464-410x.2010.09470.x · Cited by 121
Kotelevets, L., van Hengel, J., Bruyneel, E. A., Mareel, M. M. K., Roy, F. M. V., & Chastre, E. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200105109 · Cited by 118
Verhagen, P. C. M. S., van Duijn, P. W., Hermans, K., Looijenga, L. H. J., van Gurp, R., Stoop, H., van der Kwast, T., & Trapman, J. (2006) · The Journal of Pathology · doi:10.1002/path.1929 · Cited by 108
PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate
Dong, J., Sipe, T. W., Hyytinen, E., Li, C., Heise, C. E., McClintock, D. E., Grant, C. D., Chung, L. W. K., & Frierson, H. F. (1998) · Oncogene · doi:10.1038/sj.onc.1202119 · Cited by 100
Loss of PTEN is associated with progression to androgen independence
Bertram, J., Peacock, J. W., Fazli, L., Mui, A., Chung, S. W., Cox, M., Monia, B. P., Gleave, M. E., & Ong, C. J. (2006) · The Prostate · doi:10.1002/pros.20411 · Cited by 81
Antibody-Based Profiling of the Phosphoinositide 3-Kinase Pathway in Clinical Prostate Cancer
THOMAS, G. V., Horvath, S., Smith, B. L., Crosby, K., Lebel, L. A., Schrage, M. I., Said, J. W., Kernion, J. D., Reiter, R. E., & Sawyers, C. L. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-0130 · Cited by 72
A Robust Immunohistochemical Assay for Detecting PTEN Expression in Human Tumors
Sangale, Z., Prass, C. E., Carlson, A., Tikishvili, E., DeGrado, J., Lanchbury, J. S. S., & Stone, S. (2010) · Applied immunohistochemistry & molecular morphology · doi:10.1097/pai.0b013e3181f1da13 · Cited by 69
Immunohistochemical Detection of p53 Protein in Human Prostatic Cancer
Henke, R., Krüger, E., Ayhan, N., Hübner, D., Hammerer, P. G., & Huland, H. (1994) · The Journal of Urology · doi:10.1016/s0022-5347(17)32571-5 · Cited by 62
Cdc6 and Cyclin E2 Are PTEN-Regulated Genes Associated with Human Prostate Cancer Metastasis
Wu, Z., Cho, H., Hampton, G. M., & Theodorescu, D. (2009) · Neoplasia · doi:10.1593/neo.81048 · Cited by 51
Gain of Function of p53 Cancer Mutants in Disrupting Critical DNA Damage Response Pathways
Song, H., & Xu, Y. (2007) · Cell Cycle · doi:10.4161/cc.6.13.4456 · Cited by 50
Couto, S. S., Cao, M., Duarte, P. C. X., Banach-Petrosky, W. A., Wang, S., Romanienko, P. J., Wu, H., Cardiff, R. D., Abate-Shen, C. T., & Cunha, G. R. (2009) · Differentiation · doi:10.1016/j.diff.2008.09.010 · Cited by 39
Müller, I., Wischnewski, F., Pantel, K., & Schwarzenbach, H. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-297 · Cited by 37
The role of PTEN in prostate cancer cell tropism to the bone micro-environment
Wu, Z.-N., McRoberts, K., & Theodorescu, D. (2007) · Carcinogenesis · doi:10.1093/carcin/bgm050 · Cited by 36
Osman, I., Dai, J., Mikhail, M., Navarro, D., Taneja, S. S., Lee, P., Christos, P. J., Shen, R., & Nanus, D. M. (2006) · Cancer · doi:10.1002/cncr.22312 · Cited by 34
FISH Oracle: a web server for flexible visualization of DNA copy number data in a genomic context
Mäder, M., Simon, R., Steinbiss, S., & Kurtz, S. (2011) · Journal of Clinical Bioinformatics · doi:10.1186/2043-9113-1-20 · Cited by 14
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Weischenfeldt, J., Simon, R., Feuerbach, L., Schlangen, K., Weichenhan, D., Minner, S., Wuttig, D., Warnatz, H.-J., Stehr, H., Rausch, T., et al. (2013) · Cancer Cell · doi:10.1016/j.ccr.2013.01.002 · Cited by 320
Self-citationFerraldeschi, R., Nava Rodrigues, D., Riisnaes, R., Miranda, S., Figueiredo, I., Rescigno, P., Ravi, P., Pezaro, C., Omlin, A., Lorente, D., et al. (2015) · European Urology · doi:10.1016/j.eururo.2014.10.027 · Cited by 268
A prospective investigation of PTEN loss and ERG expression in lethal prostate cancer
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PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo
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Metadata
- Authors
- Krohn, A., Diedler, T., Burkhardt, L., Mayer, P.-S., De Silva, C., Meyer-Kornblum, M., Kötschau, D., Tennstedt, P., Huang, J., Gerhäuser, C., Mader, M., Kurtz, S., Sirma, H., Saad, F., Steuber, T., Graefen, M., Plass, C., Sauter, G., Simon, R., Minner, S., & Schlomm, T.
- Venue
- The American Journal of Pathology
- Publisher
- Elsevier BV
- Published
- 2012-08
- Volume
- 181
- Issue
- 2
- Pages
- 401-412
- ISSN
- 0002-9440 (ISSN-L)
- OpenAlex
- W2054074987
- Cited by
- 324
- References
- 56
- FWCI
- 24.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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