Cited by 169Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and LipoproteinsLipid metabolism and disorders

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Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B

Hanak, Viktor, Munoz, Julian, Teague, Joe, Stanley, Alfred, Bittner, Vera·2004·The American Journal of Cardiology

DOI 10.1016/j.amjcard.2004.03.069

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Abstract

This study examined the accuracy of a triglyceride/high-density lipoprotein (HDL) cholesterol ratio of 3.8 for the prediction of low-density lipoprotein (LDL) phenotype B. The ratio of 3.8 was based on Adult Treatment Panel recommendations for normal fasting triglycerides (<150 mg/dl) and HDL cholesterol (>40 mg/dl). Fasting blood samples were obtained from 658 patients. LDL phenotype analysis was performed by nuclear magnetic resonance spectroscopy. A triglyceride/HDL cholesterol ratio of 3.8 divided the distribution of LDL phenotypes with 79% (95% confidence interval [CI] 74 to 83) of phenotype B greater than and 81% (95% CI 77 to 85) of phenotype A less than the ratio of 3.8. The ratio was reliable for identifying LDL phenotype B in men and women.

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Background
The Association of Triglyceride/HDL Ratio with In-hospital Mortality in Adult Patients Admitted for Acute Coronary Syndrome in Manila Doctors Hospital
Diansuy, N. N. P., Uy-Reyes, M. A., Seguban, J. M., Leon, K. A.-D., Pestaño, N. S., Punzalan, F. E. R., & Tumanan-Mendoza, B. A. (2018) · Philippine journal of cardiology. · doi:10.69944/pjc.39852a2411
Association between Triglyceride - High Density Lipoprotein Ratio with Angiographic Severity of Coronary Artery Disease in Patients with Non-ST Segment Elevated Myocardial Infarction
Ullah, M., Chowdhury, A. A. M., & Saha, S. (2024) · Cardiovascular Journal · doi:10.3329/cardio.v16i2.75078
CARDIOVASCULAR RISK BEFORE AND AFTER SURGICAL TREATMENT OF SEVERE OBESITY
Cardia, L., Gadducci, A. V., Pajecki, D., Santo, M. A., & de Cleva, R. (2024) · ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) · doi:10.1590/0102-6720202400066e1860 · Cited by 1
“Studies indicate that the AIP, determined by routine tests, has a strong correlation with cardiovascular risk and acute myocardial infarction regardless of gender 11,13,15 .”
Additional file 1 of Evaluating the use of novel atherogenicity indices and insulin resistance surrogate markers in predicting the risk of coronary artery disease: a case‒control investigation with comparison to traditional biomarkers
Mahdavi‐Roshan, M., Mozafarihashjin, M., Shoaibinobarian, N., Ghorbani, Z., Salari, A., Savarrakhsh, A., & Hekmatdoost, A. (2022) · Figshare · doi:10.6084/m9.figshare.21629338
Assessment of Cardiovascular-Metabolic Risk in Wistar Rats Fed a Hypercaloric Diet Supplemented with Selenium: A Preclinical Animal Study
Salina, M. V. J., Pironatto, V. H. M., dos Santos, A. A. M., Gueiber, T. D., Lima, L. G., Dechandt, E. M., Caruso, C. C., Karpinski, P. H., Figueiredo, T. M., Toledo-Junior, A. D. O., et al. (2026) · International Journal of Cardiovascular Sciences · doi:10.36660/ijcs.20250069

Authors: Hanak, V., Munoz, J., Teague, J., Stanley, A., & Bittner, V.
Affiliations: Carraway Methodist Medical Center (US)
University of Alabama at Birmingham (US)
Corresponding author: Hanak, Viktor
ORCID: Bittner, Vera
Venue: The American Journal of Cardiology
Publisher: Elsevier BV
Published: 2004-07
Volume: 94
Issue: 2
Pages: 219-222
ISSN: 0002-9149 (ISSN-L)
DOI: 10.1016/j.amjcard.2004.03.069
OpenAlex: W1981002254
Cited by: 167
References: 11
Citations by year: 2026: 1 · 2025: 3 · 2024: 6 · 2023: 3 · 2022: 10 · 2021: 12 · 2020: 9 · 2019: 12 · 2018: 9 · 2017: 7 · 2016: 6 · 2015: 17 · 2014: 9 · 2013: 13 · 2012: 13
FWCI: 3.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The American Journal of Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
Keywords: triglyceride to HDL cholesterol ratio, LDL particle size, NMR spectroscopy, dyslipidemia, fasting triglycerides, HDL cholesterol, diagnostic accuracy
MeSH terms: Aged, Female, Humans, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Magnetic Resonance Spectroscopy, Particle Size, Phenotype, Sensitivity and Specificity, Triglycerides, Logistic Models

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Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B

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