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Cited by 29Dementia and Cognitive Impairment ResearchDermatology and Skin DiseasesAlzheimer's disease research and treatments

The DOI matches its Crossref record, with a small difference in title or year; 1 of the 1 references it cites were found in a registry or an index.

Atopic dermatitis and dementia risk

Pan, Tai-Long, Bai, Ya-Mei, Cheng, Chih-Ming, Tsai, Shih-Jen, Tsai, Chia-Fen, Su, Tung-Ping, Li, Cheng-Ta, Lin, Wei-Chen, Chen, Tzeng-Ji, Liang, Chih-Sung, Chen, Mu-Hong·2021·Annals of Allergy, Asthma & Immunology
DOI 10.1016/j.anai.2021.03.001
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Abstract

Background Retrospective studies have suggested that patients with dementia have higher prevalence of atopic dermatitis (AD) than those without dementia. However, the temporal association of AD with subsequent dementia remains unknown. Objective To assess the temporal association of AD with subsequent dementia. Methods We included data of patients with AD aged 45 years and older (n = 1059) and 1:10 age, sex, residence, income, and dementia-related comorbidity-matched controls (n = 10,590) from the Taiwan National Health Insurance Research Database and reviewed their subsequent dementia development from the enrollment date to the end of 2013. Results After adjustments for dementia-related comorbidities, patients with AD were found to be more likely to develop any dementia (hazard ratio [HR], 2.02; 95% confidence interval [CI], 1.24-3.29), particularly Alzheimer's disease (HR, 3.74; 95% CI, 1.17-11.97), during the follow-up period than those in the control group. Moderate-to-severe AD was associated with a high subsequent dementia risk (HR, 4.64; 95% CI, 2.58-8.33). Sensitivity analyses with the exclusion of the first 3 (HR, 2.20; 95% CI, 1.28-3.80) or 5 (HR, 2.05; 95% CI, 1.08-3.89) years of observation revealed consistent findings. Conclusion AD may be an independent risk factor for new-onset dementia. Clinicians may monitor the trajectory of neurocognitive function among elderly patients with AD. Additional studies elucidating the pathomechanisms between AD and subsequent de…

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  • A new association between AD and an increased risk of developing dementia (OR = 2.02; 95% CI 1.24‒3.29).

    “in addition to a new association between AD and an increased risk of developing dementia (OR = 2.02; 95% CI 1.24‒3.29).126”

    From Update on the pathogenesis of atopic dermatitis. (2024) · cites this paper as [126]

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Metadata

Authors
Pan, T.-L., Bai, Y.-M., Cheng, C.-M., Tsai, S.-J., Tsai, C.-F., Su, T.-P., Li, C.-T., Lin, W.-C., Chen, T.-J., Liang, C.-S., & Chen, M.-H.
Affiliations
  • Chang Gung University of Science and Technology (TW)
  • National Yang Ming Chiao Tung University (TW)
  • Tri-Service General Hospital (TW)
Corresponding author
  • Liang, Chih-Sung
  • Chen, Mu-Hong
ORCID
Venue
Annals of Allergy, Asthma & Immunology
Publisher
Elsevier BV
Published
2021-08
Volume
127
Issue
2
Pages
200-205
ISSN
1081-1206 (ISSN-L)
DOI
10.1016/j.anai.2021.03.001
OpenAlex
W3135539016
Cited by
29
References
1
Citations by year
2026: 2 · 2025: 3 · 2024: 8 · 2023: 5 · 2022: 10 · 2021: 1
FWCI
4.31
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Annals of Allergy Asthma & Immunology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Taipei Veterans General Hospital (V106B-020, V107B-010, V107C-181, V108B-012)
  • Ministry of Science and Technology, Taiwan (107-2314-B-075-063-MY3, 108-2314-B-075 -037)
  • Yen Tjing Ling Medical Foundation (CI-109-21, CI-109-22, CI-110-30)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Keywords
atopic dermatitis, dementia, Alzheimer's disease, dementia risk factors, temporal association, moderate-to-severe atopic dermatitis, neurocognitive function, elderly patients
MeSH terms
Alzheimer Disease, Dermatitis, Atopic, Female, Humans, Male, Middle Aged, Risk, Risk Factors, Taiwan, Comorbidity, Databases, Factual

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