Prepregnancy Depressive Symptoms and Preterm Birth in the Black Women's Health Study
Open accessAbstract
PURPOSE To examine the association between prepregnancy depressive symptoms and preterm birth. METHODS The present study is a prospective investigation of prepregnancy depressive symptoms—measured by the Center for Epidemiologic Studies Depression Scale (CES-D)—and risk of preterm birth reported in the Black Women’s Health Study. With data on 2,627 singleton births (175 spontaneous and 163 medically-indicated preterm births and 2,289 term births), we used generalized estimating equation models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for potential confounders. RESULTS Relative to mothers with CES-D scores <16, the multivariable ORs of spontaneous preterm birth for mothers with CES-D scores of 16-22, 23-32, and ≥33 were 1.17 (95% CI=0.78-1.80), 1.20 (95% CI=0.69-2.10), and 2.00 (95% CI=0.94-4.25), respectively (P-trend=0.09). There was little evidence of an association between prepregnancy depressive symptoms and medically-indicated preterm birth. CONCLUSIONS Our data provide some evidence of an increased risk of spontaneous preterm birth among women with high prepregnancy depressive symptoms.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Many studies demonstrate an association between stress or depression and preterm birth, while others suggest racial disparity is an underlying factor.
“Although many studies demonstrate an association [10-15] others suggest that racial disparity [14,16,17] is an underlying factor.”
From The association between parity, infant gender, higher level of paternal education and preterm birth in Pakistan: a cohort study (2011) · cites this paper as [10]
The Introduction reports that preterm birth is more common among Black women than White women, and the Discussion describes suggestive evidence linking prepregnancy depressive symptoms to spontaneous preterm birth. But the paper does not establish racial disparity as an underlying factor in that association; instead, it calls for research on whether maternal depression contributes to the disparity. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 58 · Cited by 33
Research works printed but not linked: 1
- [29]Mohllajee AP The relation of pre-pregnancy depression with corticotropin-releasing hormone levels during pregnancy Presented at Presented at the Society for Pediatric and Perinatal Epidemiologic Research Conference Boston, Massachusetts June 2007
- Authors
- Phillips, G. S., Wise, L. A., Rich-Edwards, J. W., Stampfer, M. J., & Rosenberg, L.
- Affiliations
- Harvard University (US)
- Boston University (US)
- Brigham and Women's Hospital (US)
- Corresponding author
- Rosenberg, Lynn
- Venue
- Annals of Epidemiology
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 20
- Issue
- 1
- Pages
- 8-15
- ISSN
- 1047-2797 (ISSN-L)
- PMC
- PMC2796255
- OpenAlex
- W1971237314
- Semantic Scholar
- 0e48d44ef2f2974b420d9751a13aa58393eefad8
- Cited by
- 33
- References
- 58
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 2 · 2012: 4
- FWCI
- 2.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Funders
- Centers for Disease Control and Prevention
- U.S. Public Health Service (S324-16/18)
- National Cancer Institute (CA 58420, R01CA058420)
- Agency for Toxic Substances and Disease Registry
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Keywords
- preterm birth, spontaneous preterm birth, medically indicated preterm birth, Black women, maternal mental health, Black Women's Health Study, CES-D depression scale
- MeSH terms
- Adult, Black or African American, Depression, Female, Humans, Pregnancy, Prospective Studies, Surveys and Questionnaires, United States, Odds Ratio, Premature Birth
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
