Spectrum of Cardiovascular Diseases in Asian-American Racial/Ethnic Subgroups
Open accessAbstract
Purpose To compare the prevalence of coronary heart disease (CHD), stroke, and peripheral vascular disease (PVD) across Asian-American subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese) and non-Hispanic white (NHW) subjects in a mixed-payer, outpatient health care organization in California. Methods Electronic health records from 2007 to 2010 were examined for 94,423 Asian and NHW patients. Age-adjusted prevalence rates of CHD, stroke, and PVD, defined by physician International Classification of Diseases, Version 9, codes, were directly standardized to the NHW population. Age-adjusted odds ratios were calculated by the use of logistic regression for each Asian subgroup, by sex, compared with NHWs. Results The range of age-adjusted prevalence rates were: CHD (1.7%-5.2%), stroke (0.3%-1.8%), and PVD (0.9%-3.4%). The adjusted odds ratios of CHD were significantly higher for Filipino women (1.66; 95% confidence interval; 1.13-2.43) and men (1.47, 1.05-2.06) and Asian Indian men (1.77, 1.43-2.21), and significantly lower for Chinese women (0.72, 0.55-0.94) and men (0.78, 0.65-0.93), compared with NHWs. The odds of stroke were significantly greater for Filipino women (2.02, 1.22-3.34). The odds of PVD were generally lower for all Asian subgroups. Conclusion There is considerable heterogeneity across Asian subgroups for prevalent CHD, stroke, and PVD. Future research should disaggregate Asian subgroups and cardiovascular outcomes to inform targeted prevention and treatment efforts.
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Knowledge gaps about the health of single and multiracial Asian and Pacific Islander populations have persisted in part due to the problematic practice of aggregating broad and diverse Asian and Pacific Islander populations for research purposes.
“Knowledge gaps about the health of single and multiracial Asian and Pacific Islander populations have persisted in part due to the problematic practice of aggregating broad and diverse Asian and Pacific Islander populations for research purposes.”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [9]
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredPrevious studies have shown the prevalence of CVD among API subpopulations ranging from 1.7% to 5.2%; stroke from 0.3% to 1.8%; and peripheral vascular disease from 0.9% to 3.4%.
“Previous studies have shown the prevalence of CVD among API subpopulations ranging from 1.7% to 5.2%; stroke from 0.3% to 1.8%; and peripheral vascular disease from 0.9% to 3.4% [9].”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [9]
The Abstract Results give the exact age-adjusted ranges for stroke (0.3%–1.8%) and PVD (0.9%–3.4%). They give 1.7%–5.2% for coronary heart disease (CHD), however, not for cardiovascular disease (CVD) as a whole. The figures are this paper’s findings rather than ranges it attributes to previous studies. (LLM, conf=0.87)
Experimental — accuracy not yet measuredAggregating broad and diverse Asian and Pacific Islander populations for research purposes can result in masking the extent of health disparities across these populations, and limit efforts to identify underlying drivers of health inequity.
“This practice can result in masking the extent of health disparities across these populations, and limit efforts to identify underlying drivers of health inequity [9-11].”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [9]
The Introduction says aggregated Asian-American data can mask subgroup differences, and the Discussion reports that aggregation obscures marked differences in cardiovascular disease prevalence. The Discussion also calls for subgroup-specific risk-factor research to better understand those differences. The paper does not examine Pacific Islanders or health disparities beyond cardiovascular disease, so the claim is broader than its evidence. (LLM, conf=0.86)
Experimental — accuracy not yet measuredLimited evidence suggests that there is up to a six-fold difference in CVD rates among API subpopulations.
“Limited evidence suggests that there is up to a six-fold difference in CVD rates among API subpopulations.”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [9]
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- Authors
- Holland, A. T., Wong, E. C., Lauderdale, D. S., & Palaniappan, L. P.
- Affiliations
- Palo Alto Medical Foundation (US)
- University of Chicago (US)
- Corresponding author
- Palaniappan, Latha P.
- Venue
- Annals of Epidemiology
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 21
- Issue
- 8
- Pages
- 608-614
- ISSN
- 1047-2797 (ISSN-L)
- PMC
- PMC3215504
- OpenAlex
- W2120921414
- Cited by
- 106
- References
- 35
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 5 · 2023: 8 · 2022: 8 · 2021: 11 · 2020: 4 · 2019: 4 · 2018: 5 · 2017: 9 · 2016: 14 · 2015: 9 · 2014: 9 · 2013: 4 · 2012: 7
- FWCI
- 4.82
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK081371)
- Topics
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- cardiovascular disease, Asian Americans, racial and ethnic subgroups, coronary artery disease, stroke, peripheral vascular disease, disease prevalence, Asian Indians, Chinese, Filipinos, Japanese, Korean language, Vietnamese, sex differences, ethnic disparities
- MeSH terms
- Adult, Age Factors, Asian, California, Cardiovascular Diseases, China, Cross-Sectional Studies, Female, Humans, India, Japan, Korea, Male, Philippines, Sex Factors, Vietnam, White People
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