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LBA33 A first-in-human phase I study of a novel KRAS G12D inhibitor HRS-4642 in patients with advanced solid tumors harboring KRAS G12D mutation
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Sorted by citations
Differential Response and Resistance to KRAS-Targeted Therapy
Liu, Z., Lenz, H., Yu, J., & Zhang, L. (2025) · Molecular Carcinogenesis · doi:10.1002/mc.23908 · Cited by 7
Metadata
- Authors
- Zhou, C., Li, W., Song, Z., Zhang, Y., Zhang, Y., Huang, D., Yang, Z., Zhou, M., Mao, R., Huang, C., Li, X., & Wang, J.
- Affiliations
- Tongji University (CN)
- Zhejiang Cancer Hospital (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Jiangsu Hengrui Medicine (China) (CN)
- Venue
- Annals of Oncology
- Publisher
- Elsevier BV
- Published
- 2023-10
- Volume
- 34
- Pages
- S1273
- ISSN
- 0923-7534 (ISSN-L)
- OpenAlex
- W4387809621
- Cited by
- 59
- References
- 0
- Citations by year
- 2026: 12 · 2025: 29 · 2024: 17 · 2023: 1
- Type
- conference abstract
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Annals of Oncology (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Melanoma and MAPK Pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Tyrosine Phosphatases
- Keywords
- KRAS G12D inhibitors, KRAS G12D mutation, RAS-mutant cancers, advanced solid tumors, dose escalation, small-molecule kinase inhibitors
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