Cited by 766Music Therapy and HealthNeuroscience and Music PerceptionMusic Education and Analysis

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The Anxiety‐ and Pain‐Reducing Effects of Music Interventions: A Systematic Review

Nilsson, Ulrica·2008·AORN Journal

DOI 10.1016/j.aorn.2007.09.013

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Abstract

Musical interventions have been used in health care settings to reduce patient pain, anxiety, and stress, although the exact mechanism of these therapies is not well understood. This article provides a systematic review of 42 randomized controlled trials of the effects of music interventions in perioperative settings. Music intervention had positive effects on reducing patients' anxiety and pain in approximately half of the reviewed studies. Further research into music therapy is warranted in light of the low cost of implementation and the potential ability of music to reduce perioperative patient distress.

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Music for pain relief
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10.1080/J354v19n03_05 · DOI

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“…review of 393 studies on the efficacy of music therapy in children (e.g. RCT, children aged 1 month to 18 years) Clinical procedures X Pain ↓ ; anxiety ↓ Nilsson (2008 ) Systematic review of 42 RCTs Music has positive effects in approximately half of the reviewed studies, pain ↓ ; anxiety…”
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Background
Alternative Medicine: A Recent Overview
Akter, S., Hasan, M. N., Rokeya, B., Akhter, H., Gazi, M. S., Sabrin, F., & Kim, S. S. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97039 · Cited by 19
Effect of personalized musical intervention on burden of care in dental implant surgery: A pilot randomized controlled trial
Bertacco, M., Soyeux, O., Durand, R., Boudrias, P., Wiseman, L., Rompre, P. H., Rainville, P., Emami, E., & Gosselin, N. H. (2022) · Journal of Dentistry · doi:10.1016/j.jdent.2022.104091 · Cited by 18
Effect of Self-Chosen Music in Alleviating the Burden on Family Caregivers of Patients with Advanced Cancer: A Randomised Controlled Trial
Valero-Cantero, I., Casals, C., Espinar-Toledo, M., Barón-López, F. J., Martínez-Valero, F. J., Soler, N. G., & Vázquez‐Sánchez, M. Á. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20054662 · Cited by 24
“The mechanism underlying these effects is still not clearly understood, but in contrast to the impact of a stressful situation, relaxing music is known to modulate the autonomous nervous system [33] and lower plasma cortisol levels [34], among other physiological responses associated with stress reduction and enhanced…”
Background
Effect of audio and virtual reality distraction on the dental anxiety of children with mild intellectual disability
Mehrotra, D., Shetty, A. A., Rai, K., & Kumara (2023) · Special Care in Dentistry · doi:10.1111/scd.12932 · Cited by 20
The Effects of Music on Diminishing Anxiety Among Preoperative Patients
Thompson, M., Moe, K. A., & Lewis, C. P. (2014) · Journal of Radiology Nursing · doi:10.1016/j.jradnu.2014.10.005 · Cited by 18
Impact of Music Distraction on Dental Anxiety in Children Having Intellectual Disability
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Music in the cath lab: who should select it?
Goertz, W., Dominick, K., Heussen, N., & Dahl, J. V. (2011) · Clinical Research in Cardiology · doi:10.1007/s00392-010-0256-1 · Cited by 19
“The anxiolytic and analgesic effects of music have been described in previous trials [1–18]; these effects are governed by neurochemical triggers resulting in a release of endogenous opioids, regulatory changes of the central nervous system and endocrinologic arousals, as well as activation of the dopaminergic system.”
The effect of specific music instrumentation on anxiety reduction in university music students: A feasibility study
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The effect of a stress and anxiety coping programme on objective structured clinical exam performance in medical students, a randomised clinical trial
Yalçın, B. M., Ünal, M., Pirdal, H., & Karahan, T. F. (2015) · Educational Psychology · doi:10.1080/01443410.2015.1050355 · Cited by 16
“Studies show that (Nilsson, 2008) there are growing experimental evidences attesting that some kind of music (gentle and relaxing) may modulate cardiac and neurological functions and have biochemical stress-reducing effects (Cervellin & Lippi, 2011).”
Emotions in Indian music history: anxiety in late Mughal Hindustan
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A web app-based music intervention reduces experimental thermal pain: A randomized trial on preferred versus least-liked music style
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Music reduces state anxiety scores in patients undergoing pleural procedures: a randomised controlled trial
Mackintosh, J. A., Cone, G., Harland, K., & Sriram, K. B. (2018) · Internal Medicine Journal · doi:10.1111/imj.13738 · Cited by 16
Arts and Music in Healthcare: An overview of the medical literature: 2004-2011
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Medicine’s Melodies: On the Costs & Benefits of Music, Soundscapes, & Noise in Healthcare Settings
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“There is even evidence to suggest that painful procedures can be made a little less unpleasant/painful by having the patient focus their attention on a pleasing tune or two [10-13].”
Background
Effect of live oud music on physiological and psychological parameters in patients undergoing cardiac surgery
Luis, M., Doss, R., Zayed, B., & Yacoub, M. H. (2019) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2019.17 · Cited by 18
The Effect of Music on Heart Rate
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Environmental noise exposure and natural sound intervention in hospital interventional therapy rooms: Effects on patient perception, physiological and psychological outcomes
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Does music from noise-canceling headphones have a beneficial effect on men undergoing transrectal ultrasound-guided prostate biopsy?
Lee, B.-C., Kim, H. O., Chung, H. S., Heo, S. H., Jeong, Y. Y., Kim, M. S., Hwang, E. C., Jung, S. I., Kwon, D., & Park, K. (2021) · Prostate International · doi:10.1016/j.prnil.2021.02.001 · Cited by 15
Effects of participant-selected versus researcher-selected music on stress and mood – The role of gender
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“PS music is suggested to yield stronger health benefits than RS music (Nilsson, 2008).”
Music to reduce pain and anxiety in cystoscopy: a systematic review and meta-analysis
García‐Perdomo, H. A., Cardona, L. M. M., Cordoba-Wagner, M. J., & Zapata-Copete, J. A. (2018) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2018-0095 · Cited by 15
Affordances of music composing software for learning mathematics at primary schools
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“Music in general has been found to, for example, reduce stress and anxiety (Nilsson 2008), support literacy development (Paquette and Rieg 2008), enhance motivation to exercise (Edworthy and Waring 2006) and affect feelings (Habibi and Damasio 2014), which have holistic positive effects on a persons’ life (Thompson 20…”
Background
Neuronal Effects of Listening to Entrainment Music Versus Preferred Music in Patients With Chronic Cancer Pain as Measured via EEG and LORETA Imaging
Hunt, A. M., Fachner, J. C., Clark‐Vetri, R., Raffa, R. B., Rupnow-Kidd, C., Maidhof, C., & Dileo, C. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.588788 · Cited by 17
“Subsequent research adds to this evidence base, demonstrating that listening to music reduces both acute and chronic pain (Nilsson, 2008; Guétin et al., 2012; Roy et al., 2012; Garza-Villarreal et al., 2014; Korhan et al., 2014).”
Background
Music therapy and psychological-clinical impact in surgery: a systematic review
Caponnetto, P., LaMattina, G., & Quattropani, M. C. A. (2022) · Health Psychology Research · doi:10.52965/001c.38615 · Cited by 15
Alleviating Anxiety and Preventing Panic Attacks in the Surgical Patient
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The effect of audiovisual distraction on the tolerability of flexible bronchoscopy: a randomized trial
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Effects of music intervention on anxiety and pain reduction in ambulatory maxillofacial and otorhinolaryngology surgery: a descriptive survey of 27 cases
Keilani, C., Simondet, N., Maalouf, R., Yigitoglu, A., Bougrine, A., Simon, D., & Fligny, I. (2017) · Oral and Maxillofacial Surgery · doi:10.1007/s10006-017-0616-3 · Cited by 16
“A 2008 and 2015 systematic review of randomized controlled trials of the effects of music interventions in peri and postoperative settings in general surgery concluded that music intervention had positive effects on reducing patients’ anxiety and pain [6, 7].”
Background
Does Audiovisual Stimulation With Music and Nature Sights (MuViCure) Reduce Pain and Discomfort During Placement of a Femoral Nerve Block?
Nikolajsen, L., Lyndgaard, K., Schriver, N. B., & Moller, J. F. (2009) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2008.10.005 · Cited by 14
Impact of Music on Postoperative Pain, Anxiety, and Narcotic Use After Robotic Prostatectomy: A Randomized Controlled Trial
Mishra, K., Jesse, E., Bukavina, L., Sopko, E., Arojo, I., Fernstrum, A. J., Ray, A. W., Mahran, A., Calaway, A. C., Block, S., et al. (2022) · Journal of the Advanced Practitioner in Oncology · doi:10.6004/jadpro.2022.13.2.3 · Cited by 14
“…and cost-effective intervention that has been shown to reduce pain, anxiety, and analgesia use within the perioperative setting in many surgical fields, including orthopedic surgery, cardiac surgery, gynecologic surgery, and several more (Hole et al., 2015; Kühlmann et al., 2018; Nilsson, 2008).”
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A prospective randomized controlled trial assessing the effect of music on patients’ anxiety in venous catheter placement procedures
Fleckenstein, F. N., Böhm, A. K., Collettini, F., Frisch, A., Lüdemann, W. M., Can, E., Gebauer, B., & Jonczyk, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-10862-0 · Cited by 14
Patients’ Perceptions of Sound and Noise Dimensions in the Dental Clinic Soundscape
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Music Therapy and Music Intervention for NSCLC Patients Undergoing PET with Fear of Cancer Recurrence
Du, Y., Guan, Y., Thome, K., & Dong, J. (2024) · Integrative Cancer Therapies · doi:10.1177/15347354241269898 · Cited by 15
“16 There are many mechanisms by which music can alleviate anxiety 17 Some researchers revealed that music has powerful therapeutic effects on the circulatory, respiratory, and endocrine systems.”
Background
Rhythm and orthopedics: The effect of music therapy in cast room procedures, a prospective clinical trial
Tolunay, T., Biçici, V., Tolunay, H., Akkurt, M. O., Arslan, A. K., Aydoğdu, A., & Bingöl, İ. (2018) · Injury · doi:10.1016/j.injury.2018.02.008 · Cited by 14
Impact of music therapy before first‐trimester instrumental termination of pregnancy: a randomised controlled trial
Belloeil, V., Cazeneuve, C. T., Leclercq, A., Mercier, M., Legendre, G., & Corroenne, R. (2020) · BJOG: an International Journal of Obstetrics and Gynaecology · doi:10.1111/1471-0528.16102 · Cited by 14

Authors: Nilsson, U.
Affiliations: Örebro University Hospital (SE)
Corresponding author: Nilsson, Ulrica
ORCID: Nilsson, Ulrica
Venue: AORN Journal
Publisher: Wiley
Published: 2008-04
Volume: 87
Issue: 4
Pages: 780-807
ISSN: 0001-2092 (ISSN-L)
1878-0369
DOI: 10.1016/j.aorn.2007.09.013
OpenAlex: W1979494212
Cited by: 766
References: 77
Citations by year: 2026: 45 · 2025: 60 · 2024: 43 · 2023: 47 · 2022: 48 · 2021: 75 · 2020: 52 · 2019: 63 · 2018: 39 · 2017: 37 · 2016: 43 · 2015: 40 · 2014: 39 · 2013: 33 · 2012: 27
FWCI: 3.24
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 2 d)
Locations: AORN Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Social Psychology › Music Therapy and Health
Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
Social Sciences › Education › Music Education and Analysis
Keywords: music intervention, music therapy, perioperative anxiety, postoperative pain, patient distress, surgical patients, stress reduction
MeSH terms: Adult, Aged, Anxiety, Female, Humans, Male, Middle Aged, Music Therapy, Operating Room Nursing, Pain, Preoperative Care, Research Design, Severity of Illness Index, Time Factors, Nursing Evaluation Research, Randomized Controlled Trials as Topic, Treatment Outcome, Evidence-Based Medicine, Perioperative Care

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The Anxiety‐ and Pain‐Reducing Effects of Music Interventions: A Systematic Review

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