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Cited by 320Spinal Cord Injury ResearchMental Health Treatment and AccessMusculoskeletal pain and rehabilitation

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Prevalence of Depression After Spinal Cord Injury: A Meta-Analysis

Williams, Ryan, Murray, Adrian·2015·Archives of Physical Medicine and Rehabilitation
DOI 10.1016/j.apmr.2014.08.016
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Abstract

Objectives To use meta-analysis to synthesize point prevalence estimates of depressive disorder diagnoses for persons who have sustained a spinal cord injury (SCI).Data sources We searched PsycINFO, PubMed, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Dissertation Abstracts International (DAI) for studies examining depression after SCI through 2013. We also conducted a manual search of the reference sections of included studies.Study selection Included studies contained persons with SCI; used a diagnostic measure of depression (ie, an unstructured, semi-structured, or structured clinical interview, and/or a clinician diagnosis); and provided a diagnosis of major or minor depressive episodes for the subjects in the study. Diagnostic criteria were based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, or the Diagnostic and Statistical Manual of Mental Disorders-Third Edition (including Research Diagnostic Criteria) criteria.Data extraction The 2 authors of this study screened the titles and abstracts of 1053 unique studies for inclusion in this meta-analysis. Nineteen studies, containing 35,676 subjects and 21 effect size estimates, were included.Data synthesis The mean prevalence estimate of depression diagnosis after SCI was 22.2%, with a lower-bound estimate of 18.7% and an upper bound estimate of 26.3%. Random effects and mixed effects models were used in this work. A small number of study moderators were explored, including sample sex composition, Diagnostic and Statistical Manual of Mental Disorders version used, data collection method (primary vs secondary), sample traumatic etiology composition, sample injury level and completeness composition, and sample diagnostic composition. Data collection method, Diagnostic and Statistical Manual of Mental Disorders version, and diagnostic composition significantly predicted variation in observed effect size estimates, with primary data collection studies having lower estimates compared with secondary data analysis studies, studies using Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnostic criteria having higher estimates compared with studies using Diagnostic and Statistical Manual of Mental Disorders, Third Edition, criteria, and samples comprising individuals diagnosed only with major depression having lower prevalence estimates.Conclusions The existing data on depression after SCI indicate that the prevalence of depression after SCI is substantially greater than that in the general medical population. These results underscore the importance of continued research on measuring depression in persons with SCI and on treatments for depression after SCI.

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Metadata

Authors
Williams, R., & Murray, A.
Affiliations
  • American Institutes for Research (US)
  • University of Memphis (US)
ORCID
Williams, Ryan
Venue
Archives of Physical Medicine and Rehabilitation
Publisher
Elsevier BV
Published
2015-01
Volume
96
Issue
1
Pages
133-140
ISSN
0003-9993 (ISSN-L)
DOI
10.1016/j.apmr.2014.08.016
OpenAlex
W2122275193
Cited by
320
References
41
Citations by year
2026: 32 · 2025: 36 · 2024: 34 · 2023: 33 · 2022: 49 · 2021: 19 · 2020: 24 · 2019: 33 · 2018: 20 · 2017: 17 · 2016: 11 · 2015: 11
FWCI
1.89
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Archives of Physical Medicine and Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Spinal Cord Injury Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords
depression, spinal cord injury, prevalence, depressive disorders, major depressive episode, psychiatric comorbidity, DSM-IV diagnostic criteria, DSM-III-R criteria, traumatic spinal cord injury
MeSH terms
Depressive Disorder, Humans, Spinal Cord Injuries, Prevalence

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