Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges

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Items 601–700 of 1,000

1. Exosomes in Atherosclerosis, a Double-Edged Sword: Their Role in Disease Pathogenesis and Their Potential as Novel Therapeutics
   Neil Patel, Deborah D. Chin, Eun Ji Chung · 2021 · The AAPS Journal
2. Potential of different cells-derived exosomal microRNA cargos for treating spinal cord injury
   Dayu Pan, Weixiao Liu, Shibo Zhu, Baoyou Fan, Nanxi Yu, Guangzhi Ning, Shiqing Feng · 2021 · Journal of Orthopaedic Translation
3. Tumor‐derived exosomes: Key players in non‐small cell lung cancer metastasis and their implication for targeted therapy
   Maryam Noor Rizwan, Yunxia Ma, Miljana Nenkov, Lai Jin, Desiree Charlotte Schröder, Martin Westermann, Nikolaus Gaßler, Yuan Chen · 2021 · Molecular Carcinogenesis
4. Overcoming the blood–brain barrier by using a multistage exosome delivery system to inhibit central nervous system lymphoma
   Xu Liu, Tian Xia, Yiran Fang, Huaqin Zuo, Xiaoqing Dong, Peipei Xu, Jian Ouyang · 2022 · Nanomedicine Nanotechnology Biology and Medicine
5. Extracellular Vesicles and Circulating Tumour Cells - complementary liquid biopsies or standalone concepts?
   Artur Słomka, Bingduo Wang, Tudor Mocan, Adelina Horhat, Arnulf Gregor Willms, Ingo G.H. Schmidt‐Wolf, Christian P. Strassburg, Maria Angeles Gonzalez-Carmona, Miroslaw Kornek, Miroslaw Kornek · 2022 · Theranostics
6. Exosomes and exosomal miRNAs: A new therapy for intervertebral disc degeneration
   Zhichao Li, Yan Wu, Guoqing Tan, Zhanwang Xu, Haipeng Xue · 2022 · Frontiers in Pharmacology
7. Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury
   Shanshan Liu, Xinyu Xiao, Zhang La, Jianwei Wang, Wei Zhao, Haichuan Liu, Rui Liao, Zhi Li, Mengxia Xu, Jiao Guo et al. · 2023 · Theranostics
8. Exosomal PD-L1 detection in cancer predictive biomarker for response to immune checkpoint blockade therapy
   Tetsuichi Kansha, Shuai Ma, Hao Wang, Xiaotong Yu, Ying Song, Zhengyang Guo, Jiagui Song, Lixiang Xue, Jianling Yang · 2025 · Frontiers in Immunology
9. RNA-Guided Adenosine Deaminases: Advances and Challenges for Therapeutic RNA Editing
   Genghao Chen, Dhruva Katrekar, Prashant Mali · 2019 · Biochemistry
10. The Potential of Milk-Derived Exosomes for Drug Delivery
    Shuyuan Li, Yue Tang, Yushun Dou · 2020 · Current Drug Delivery
11. Platform technologies and human cell lines for the production of therapeutic exosomes
    Jiyoon Kim, Yonghee Song, Cheol Hyoung Park, Chulhee Choi · 2021 · Extracellular Vesicles and Circulating Nucleic Acids
12. Recent Progress of Exosomes in Multiple Myeloma: Pathogenesis, Diagnosis, Prognosis and Therapeutic Strategies
    Xi Wang, Lin He, Xiaobing Huang, Shasha Zhang, Wanjun Cao, Feifei Che, Yi Zhun Zhu, Jingying Dai · 2021 · Cancers
13. Novel approaches of the nanotechnology-based drug delivery systems for knee joint injuries: A review
    Ayesha Younas, Hongzhou Gu, Yongxing Zhao, Nan Zhang · 2021 · International Journal of Pharmaceutics
14. Rapid and label-free cancer theranostics via in situ bio-self-assembled DNA–gold nanostructures loaded exosomes
    Farouk Semcheddine, Nida El Islem Guissi, Weiwei Liu, Tayyaba, Lv Gang, Hui Jiang, Xuemei Wang · 2021 · Materials Horizons
15. Nanoparticle technologies: Recent state of the art and emerging opportunities
    Arun Parupudi, Sri Hari Raju Mulagapati, J. Anand Subramony · 2021 · Elsevier eBooks
16. Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood–Brain Barrier System
    Antonios Fikatas, Jonas Dehairs, Sam Noppen, Jordi Doijen, Frank Vanderhoydonc, Eef Meyen, Johannes V. Swinnen, Christophe C. Pannecouque, Dominique Schols · 2021 · Viruses
17. Mesenchymal Stem Cell-Derived Extracellular Vesicles as Non-Coding RNA Therapeutic Vehicles in Autoimmune Diseases
    Olga Martínez-Arroyo, Ana Ortega, María José Forner, Raquel Cortés · 2022 · Pharmaceutics
18. The immunosuppressive tumor microenvironment in hepatocellular carcinoma-current situation and outlook
    Zhou Zhou, Yuhao Hu, Yixuan Wu, Qianyi Qi, Jianxin Wang, Lin Chen, Feng Wang · 2022 · Molecular Immunology
19. The combination of Alisma and Atractylodes ameliorates cerebral ischaemia/reperfusion injury by negatively regulating astrocyte-derived exosomal miR-200a-3p/141-3p by targeting SIRT1
    Wei Wei, Huihong Li, Yunfei Deng, Xiaoqing Zheng, Yangjie Zhou, Xiehua Xue · 2023 · Journal of Ethnopharmacology
20. Exploring potential of exosomes drug delivery system in the treatment of cancer: Advances and prospective
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21. Can naturally occurring nanoparticle-based targeted drug delivery effectively treat inflammatory bowel disease?
    Chunhua Yang, Didier Merlin · 2019 · Expert Opinion on Drug Delivery
22. Extracellular vesicles as novel drug delivery systems to target cancer and other diseases: Recent advancements and future perspectives
    Divya Ramesh, Shankar M Bakkannavar, Vinutha R Bhat, Krishna Sharan · 2023 · F1000Research
23. The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead
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24. The Epstein–Barr Virus LMP1 Interactome: Biological Implications and Therapeutic Targets
    Mujeeb R. Cheerathodi, David G. Meckes · 2018 · Future Virology
25. Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF
    Alina Venereo-Sánchez, Kelly M. Fulton, Krisztina Koczka, Susan M. Twine, Parminder S. Chahal, Sven Ansorge, Rénald Gilbert, Olivier Henry, Amine Kamen · 2019 · Vaccine
26. Exosome as a Natural Gene Delivery Vector for Cancer Treatment
    Prasad Pofali, Adrita Mondal, Vaishali Yogesh Londhe · 2020 · Current Cancer Drug Targets
27. Cardiac Exosomes in Ischemic Heart Disease—A Narrative Review
    Øystein Røsand, Morten A. Høydal · 2021 · Diagnostics
28. Mesenchymal stem cell‐derived small extracellular vesicles as cell‐free therapy: Perspectives in periodontal regeneration
    Solen Novello, Pascal Pellen‐Mussi, Sylvie Jeanne · 2021 · Journal of Periodontal Research
29. The significance of exosomal RNAs in the development, diagnosis, and treatment of pancreatic cancer
    Zheng Zhao, Guiping Zhao, Shuyue Yang, Shengtao Zhu, Shutian Zhang, Peng Li · 2021 · Cancer Cell International
30. Extracellular vesicles as novel therapeutic targets and diagnosis markers
    Yu Zhang, Weiliang Wu, Xiangbin Pan, Yanli Wang, Chengjie Wu, Lin Lu, Xiyong Yu, Yangxin Li · 2022 · Extracellular Vesicle
31. Endogenous Lipid Carriers—Bench-to-Bedside Roadblocks in Production and Drug Loading of Exosomes
    Terjahna Richards, Himaxi Patel, Ketan R. Patel, Frank Schanne · 2023 · Pharmaceuticals
32. Biomaterials and extracellular vesicles in cell-free therapy for bone repair and regeneration: Future line of treatment in regenerative medicine
    Ketki Holkar, Anuradha Vaidya, Prasad S. Pethe, Vaijayanti Prakash Kale, Ganesh C. Ingavle · 2020 · Materialia
33. Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway
    Qin, Danqing, Wang, Chunjuan, Li, Dong, Guo, Shougang · 2024 · Journal of Biological Chemistry
34. Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis
    Hae-In Lee, Min-Joo Ahn, Jae‐Kwang Yoo, So‐Hee Ahn, Seon Young Park, Hyangmi Seo, Moon‐Ju Kim, Yu Jeong Lee, Hyun Hee Jang, Seung Cheol Shim et al. · 2024 · Arthritis Research & Therapy
35. Prospectives and challenges of nano-tailored biomaterials-assisted biological molecules delivery for tissue engineering purposes
    Mohammad El-Nablaway, Fatema Rashed, Ehab S. Taher, Tarek Foda, Ahmed Abdeen, Mohamed Abdo, Liana Mihaela Fericean, Ioan Bănățean-Dunea, Ostan Mihaela, Ştefania Dinu et al. · 2024 · Life Sciences
36. Endothelial progenitor cell-derived extracellular vesicles: the world of potential prospects for the treatment of cardiovascular diseases
    Dexin Chen, Chuanghong Lu, Na Na, Rui‐Xing Yin, Feng Huang · 2024 · Cell & Bioscience
37. Potential neuroprotective role of astroglial exosomes against smoking-induced oxidative stress and HIV-1 replication in the central nervous system
    Sabina Ranjit, Benjamin J. Patters, Kelli A. Gerth, Sanjana Haque, Sanjeev Choudhary, Santosh Kumar · 2018 · Expert Opinion on Therapeutic Targets
38. Regulatory Roles of HSP90-Rich Extracellular Vesicles
    Takanori Eguchi, Kisho Ono, Kazumi Kawata, Kuniaki Okamoto, Stuart K. Calderwood · 2019 · Heat shock proteins
39. A CRISPR-Cas9 repressor for epigenetic silencing of KRAS
    Jingwen Liu, Meiyan Sun, Kwang Bog Cho, Xiang Gao, Bin Guo · 2020 · Pharmacological Research
40. MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs
    Louie Semaan, Qingning Zeng, Yong Lü, Yi Zhang, Mehdi Mohamad Zreik, Mohamad Baqer Chamseddine, Michael Chopp, Zheng Gang Zhang, Dilip Moonka · 2021 · Oncotarget
41. Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment
    Andrew E. Massey, Shabnam Malik, Mohammad Sikander, Kyle D. Doxtater, Manish Kumar Tripathi, Sheema Khan, Murali Mohan Yallapu, Meena Jaggi, Subhash C. Chauhan, Bilal Bin Hafeez · 2021 · International Journal of Molecular Sciences
42. New Insights Into the Regulatory Roles of Extracellular Vesicles in Tumor Angiogenesis and Their Clinical Implications
    Maohua Huang, Yuhe Lei, Yinqin Zhong, Chiwing Chung, Mei Wang, Min Hu, Lijuan Deng · 2021 · Frontiers in Cell and Developmental Biology
43. Multifunctional Nanocarriers for Alzheimer’s Disease: Befriending the Barriers
    Mohammad Azam Ansari, Takshashila Tripathi, Baskar Venkidasamy, Alan Monziani, Govindasamy Rajakumar, Mohammad N. Alomary, Sami A. Alyahya, Oriane Onimus, Naomi D’souza, Md. Abul Barkat et al. · 2023 · Molecular Neurobiology
44. Vesicles as antibiotic carrier: State of art
    Verdiana Marchianò, María Matos, Esther Serrano‐Pertierra, Gemma Gutiérrez, María Carmen Blanco‐López · 2020 · International Journal of Pharmaceutics
45. Aspirin loaded extracellular vesicles inhibit inflammation of macrophages via switching metabolic phenotype in periodontitis
    Yuanyuan Shi, Ruijie Zhang, Ningning Da, Yiming Wang, Jianhua Yang, Bei Li, Xiaoning He · 2023 · Biochemical and Biophysical Research Communications
46. Engineered extracellular vesicle-based gene therapy for the treatment of discogenic back pain
    Shirley N. Tang, Ana I. Salazar‐Puerta, Mary K. Heimann, Kyle Kuchynsky, Maria Angelica Rincon‐Benavides, Mia Kordowski, Gilian Gunsch, Lucy Bodine, Khady Diop, Connor Gantt et al. · 2024 · Biomaterials
47. Exosomes for neurodegenerative diseases: diagnosis and targeted therapy
    Hui Tao, Bo Gao · 2024 · Journal of Neurology
48. Genetically Engineered Cellular Nanovesicles: Theories, Design and Perspective
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49. Genetic Substrate Reduction Therapy: A Promising Approach for Lysosomal Storage Disorders
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50. Nanovesicle-mediated delivery of anticancer agents effectively induced cell death and regressed intrahepatic tumors in athymic mice
    Joseph George, Irene K. Yan, Tushar C. Patel · 2018 · Laboratory Investigation
51. Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment
    Stephanie M. Kronstadt, Alex Eli Pottash, Daniel H. Levy, Sheng Wang, Wei Chao, Steven M. Jay · 2021 · Advanced Therapeutics
52. Long chain fatty acids can form aggregates and affect the membrane integrity
    Gülen Melike Demirbolat, Göknil Pelin Coşkun, Ömer Erdoğan, Özge Dağdeviren Çevik · 2021 · Colloids and Surfaces B Biointerfaces
53. Plasma Exosomes at the Late Phase of Remote Ischemic Pre-conditioning Attenuate Myocardial Ischemia-Reperfusion Injury Through Transferring miR-126a-3p
    Danni Li, Yang Zhao, Zhang Chuyi, Fan Wang, Yan Zhou, Sanqing Jin · 2021 · Frontiers in Cardiovascular Medicine
54. Exosomal microRNAs have great potential in the neurorestorative therapy for traumatic brain injury
    Yongxiang Yang, Haihong Yang, Yongjian Yang, Yuan Ma · 2022 · Experimental Neurology
55. Update on the application of mesenchymal stem cell-derived exosomes in the treatment of Parkinson's disease: A systematic review
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56. Research advances and challenges in tissue-derived extracellular vesicles
    Zhengke Zhi, Qiaochu Sun, Weibing Tang · 2022 · Frontiers in Molecular Biosciences
57. Exosome‐mediated PROTACs delivery to target viral infections
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58. Engineered exosomes for tissue regeneration: from biouptake, functionalization and biosafety to applications
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59. Fusion of Exosomes and Nanotechnology: Cutting-Edge Cancer Theranostics
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60. Herb Extracellular Vesicle-Chitosan-PEGylated Graphene Oxide Conjugate Delivers Estrogen Receptor α Targeting siRNA to Breast Cancer Cells
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61. Intriguing Biomedical Applications of Synthetic and Natural Cell-Derived Vesicles: A Comparative Overview
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62. Advances in nucleic acid therapeutics: structures, delivery systems, and future perspectives in cancer treatment
    Leqi Zhang, Wenting Lou, Jianwei Wang · 2024 · Clinical and Experimental Medicine
63. Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Spinal Cord Injury
    Jing An, Bo Chen, Rui Zhang, Ding Tian, Kuohao Shi, Lingling Zhang, Gaorong Zhang, Jingchao Wang, Hao Yang · 2024 · Molecular Neurobiology
64. Superparamagnetic lipid-based hybrid nanosystems for drug delivery
    Elodie Millart, Sylviane Lesieur, Vincent Faivre · 2018 · Expert Opinion on Drug Delivery
65. MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives
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66. Extracellular vesicles in urologic malignancies—Implementations for future cancer care
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67. Anti-c-myc RNAi-Based Onconanotherapeutics
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68. Therapeutic potential of mesenchymal stem cell-derived exosomes as a cell-free therapy approach for the treatment of skin, bone, and cartilage defects
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69. Exosomal long non-coding RNA LIPCAR derived from oxLDL-treated THP-1 cells regulates the proliferation of human umbilical vein endothelial cells and human vascular smooth muscle cells
    Nan Hu, Xixi Zeng, Feifei Tang, Sizheng Xiong · 2021 · Biochemical and Biophysical Research Communications
70. [Retracted] Mesenchymal Stem Cell‐Derived Exosomes and Their Potential Agents in Hematological Diseases
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71. Composition, Biogenesis, and Role of Exosomes in Tumor Development
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72. Exosomes and Biomaterials: In Search of a New Therapeutic Strategy for Multiple Sclerosis
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73. Comparing extracellular vesicles from four different cell origins for intracellular drug delivery to pancreatic cancer cells: Small or large vesicles?
    Tianjiao Geng, Song Yee Paek, Euphemia Yee Leung, Lawrence W. Chamley, Zimei Wu · 2024 · Journal of Drug Delivery Science and Technology
74. Apoptotic vesicles rescue impaired mesenchymal stem cells and their therapeutic capacity for osteoporosis by restoring miR-145a-5p deficiency
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75. Pancreatic Cancer: Recent Advances in Nanoformulation-Based Therapies
    Preshita Prafulla Desai, David Kong Ann, Jeffrey Wang, Sunil V. Prabhu · 2018 · Critical Reviews in Therapeutic Drug Carrier Systems
76. Exosome cargo in milk as a potential marker of cow health
    Monica Colitti, Sandy Sgorlon, Bruno Stefanon · 2020 · Journal of Dairy Research
77. Extracellular Vesicles as Drug Delivery System for the Treatment of Neurodegenerative Disorders: Optimization of the Cell Source
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78. Bioprobes-regulated precision biosensing of exosomes: From the nanovesicle surface to the inside
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79. Exosome-mediated aptamer S58 reduces fibrosis in a rat glaucoma filtration surgery model
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80. Continuous-flow label-free size fractionation of extracellular vesicles through electrothermal fluid rolls and dielectrophoresis synergistically integrated in a microfluidic device
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81. Brain‐Targeted Exosomes‐Based Drug Delivery System to Overcome the Treatment Bottleneck of Brainstem Glioma
    Junge Chen, Shaobo Shan, Bozhang Xia, Liwei Zhang, Xing‐Jie Liang · 2023 · Advanced Functional Materials
82. Cell-Derived Vesicles for in Vitro and in Vivo Targeted Therapeutic Delivery
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83. Copper/Tin Nanocomposites‐Loaded Exosomes Induce Apoptosis and Cell Cycle Arrest at G0/G1 Phase in Skin Cancer Cell Line
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84. Extracellular Vesicles: Diagnostic and Therapeutic Applications in Cancer
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85. Exosome-mediated therapeutic delivery: A new horizon for human neurodegenerative disorders’ treatment (with a focus on siRNA delivery improvement)
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86. Exosomes May Be the Potential New Direction of Research in Osteoarthritis Management
    Cheng Ju, Renfeng Liu, Yu Zhang, Feifei Zhang, Jun Sun, Xiaobin Lv, Zhiping Zhang · 2019 · BioMed Research International
87. Biogenesis, Biologic Function and Clinical Potential of Exosomes in Different Diseases
    Amany Magdy Beshbishy, Saad Ali Alghamdi, ThankGod E. Onyiche, Muhammad Zahoor, Nallely Rivero-Pérez, Adrián Zaragoza-Bastida, Mohamed A. Ghorab, Ahmed Kh. Meshaal, Mohamed Ahmed El-Esawi, ‏Helal F. Hetta et al. · 2020 · Applied Sciences
88. Role of Extracellular Vesicles in Substance Abuse and HIV-Related Neurological Pathologies
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89. Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo
    Linglong Deng, Hannah Elizabeth Petrek, Mei‐Juan Tu, Neelu Batra, Aixi Yu, Ai‐Ming Yu · 2021 · Acta Pharmaceutica Sinica B
90. Toxicological Profile of Umbilical Cord Blood-Derived Small Extracellular Vesicles
    Sílvia C. Rodrigues, Renato M. S. Cardoso, Cláudia F. Gomes, Filipe V. Duarte, Patrícia C. Freire, Ricardo Pires das Neves, Joana Simões‐Correia · 2021 · Membranes
91. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration
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92. Follicular fluid extracellular vesicle miRNAs and ovarian aging
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93. Multifaceted Nano-DEV-IL for Sustained Release of IL-12 to Avert the Immunosuppressive Tumor Microenvironment and IL-12-Associated Toxicities
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94. Adipose Tissue-Derived Stem Cell Extracellular Vesicles Suppress Glioblastoma Proliferation, Invasiveness and Angiogenesis
    Dovydas Gečys, Rūta Skredėnienė, Emilija Gečytė, Arūnas Kazlauskas, Ingrida Balnytė, Aistė Jekabsone · 2023 · Cells
95. Extracellular vesicles in oral squamous cell carcinoma: current progress and future prospect
    Yanqi Zhang, Jianing Liu, Shiyu Liu, Lu Yu, Siying Liu, Meng Li, Fang Jin · 2023 · Frontiers in Bioengineering and Biotechnology
96. Exosomal miRNAs and breast cancer: a complex theranostics interlink with clinical significance
    Sayantanee Mukherjee, Rajib Dhar, Swathi Jonnalagadda, Sukhamoy Gorai, Sagnik Nag, Rishav Kar, Nobendu Mukerjee, Dattatreya Mukherjee, Rishabh Vatsa, Arikketh Devi et al. · 2023 · Biomarkers
97. Impact of exosome therapy on pancreatic cancer and its progression
    Mohamed El‐Tanani, Hamdi Nsairat, Ismail Ibrahim Matalka, Alaa A. A. Aljabali, Vijay Kumar Mishra, Yachana Mishra, Gowhar A. Naikoo, Sai Raghuveer Chava, Nitin B. Charbe, Murtaza M. Tambuwala · 2023 · Medical Oncology
98. Investigating Neuroplasticity Changes Reflected by BDNF Levels in Astrocyte-Derived Extracellular Vesicles in Patients with Depression
    Kun Li, Kun Wang, Shu‐xian Xu, Xin‐hui Xie, Yan Tang, Lihong Zhang, Zhongchun Liu · 2024 · International Journal of Nanomedicine
99. Contemporary Formulations for Drug Delivery of Anticancer Bioactive Compounds
    Darinka Gjorgieva Ackova, Katarina Smilkov, Darko Bosnakovski · 2019 · Recent Patents on Anti-Cancer Drug Discovery
100. Preclinical Experimental Applications of miRNA Loaded BMSC Extracellular Vesicles
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