Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NF-κB pathway through microbiota–gut–brain axis
Zhao, Zhe, Li, Fangyuan, Ning, Jingwen, Peng, Ran, Shang, Junmei, Liu, Hui, Shang, Meiyu, Bao, Xiu-Qi +1 more·2021·Acta Pharmaceutica Sinica B
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- Improving Cognitive Function Through Inhibiting the Activation of Microglia by Jia Wei Kai Xin San on Alzheimer's Disease RatsYang Liu, Shi-Yu Chen, Jingjing Ma, Yuqing Jiang, Feng Gu, Zheng Hong-xin · 2022 · International Journal of Pharmacology
- Discovery of 3-Bromoflavone Derivative D5 as a Novel TLR4-MD2 Antagonist For The Treatment of Acute Lung Injury And SepsisXu Cheng, Yijie Wang, Hao Wang, Jing Xu, Lin Wang, Shouguo Zhang, Shu‐Chen Liu, Tao Peng · 2023 · SSRN Electronic Journal
- Pharmacokinetics and multi-peak phenomenon analysis of novel anti-Parkinson’s drug FLZ after multi-dose in cynomolgus monkeysJiayu Li, Shuofeng Zhang, Rui Chen · 2024 · Xenobiotica
- Artemether Restores the Barrier Damage and Intestinal Dysbiosis to Alleviate Postoperative Cognitive Dysfunction Via Inhibiting Tlr4/Myd88/Traf6 PathwayHong Yu, Siqi Chen, Xuan Li, Jingrun Lin, Zhuming Xue, Jiayi Liu, Weijie Violet Lin, Lin Sen Cao · 2024 · SSRN Electronic Journal
- Systemic exposure to rotenone toxicity induces gastro-inflammatory damage in mice: protective response of Zingiber officinale Roscoe extractOlusegun G. Adebayo, Emmanuel Uchechukwu Modo, Blessing Ogechukwu Orji, Joseph Chimezie, Iheanyichukwu Wopara, Adebimpe V. Masanwoola, Patrick Chukwuyenum Ichipi-Ifukor, Benjamin Oritsemuelebi, Kelly Iria Esezobor · 2025 · Nutrire
- The potential role of gut microbiota, short-chain fatty acids, and intestinal permeability in obesity: A scoping reviewQi Tang, Yetian Liang, PeiYuan Liu, Beibei Tong, Sikai Shan, HongBo Chen, Shaomei Shang · 2025 · Interdisciplinary Nursing Research
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- D-mannose alleviates rotenone-induced PD mouse model through microbiota-gut-brain axisYan Hong, Chang Ge, Jing Jin, Yifei Gao, Yujie Tang · 2026 · Scientific Reports
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- Gut Microbiota Remodeling after Fecal Microbiota Transplantation Is Associated with Reduced Inflammation and Cardiac Injury in Fluoride-Arsenic Co-Exposed RatsXiaoxuan Li, Xiaolin Tian, Peng Liu, Jiyu Yuan, Penghui Liu, Xiaodong Ying, Hengyi Guo, Chenyue Ma, Di Zhao, Ruijing Xuan et al. · 2026 · Biological Trace Element Research
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- Muribaculaceae regulate β-muricholic acid to target S1PR2 signaling and reduce neurological injury in intracerebral hemorrhageSong Liu, Yi Lv · 2026 · Experimental Neurology
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- Protective Effects of Cubebin on Neuroinflammation, Neurotransmitter Depletion, Mitochondrial Dysfunction, and Motor Disability in Parkinsonian RatsOmar Awad Alsaidan, Ameeduzzafar Zafar, Naveed Ahmad, Nadeem Sayyed, Sami Ibrahim Alzarea · 2026 · Journal of Disability Research
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