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Lung Transplantation for Patients With High Lung Allocation Score: Single-Center Experience
Open accessAbstract
Background The lung allocation score (LAS) assigns organ allocation priority based on medical urgency and the likelihood of posttransplant survival. This study is a review of a single institutional experience for lung transplantation in the era of LAS. Methods We performed a retrospective review of 527 consecutive patients, from May 2005 to February 2010, who underwent lung transplant at our institution, comprising a high LAS group (LAS≥50, n=108) and a low LAS group (LAS<50, n=419). Kaplan-Meier and univariate analyses were performed to assess postoperative mortality as a primary outcome, and length of ventilator support and intensive care unit stay as secondary outcomes. Risk factors, including demographics, pulmonary status, and surgical and donor variables, were compared. Predictors of mortality were determined using a Cox proportional hazard model. Results Survivals after 30 days, 90 days, 1 year, and 3 years were 92.6%, 87.8%, 71.5%, and 52.0%, respectively, in the high LAS group, and 96.9%, 93.5%, 83.2%, and 73.9% in the low LAS group (p<0.001). The incidence of prolonged ventilator support and the need for tracheostomy were higher, and intensive care unit stay was longer in the high LAS group. In the high LAS group, ischemic time greater than 8 hours was an independent predictor for mortality (hazard ratio: 3.080; 95% confidence interval 1.101 to 8.161, p=0.032). Conclusions Lung transplant in patients with high a LAS is associated with significantly decreased survival and increased complications compared with patients with a low LAS. Ischemic time greater than 8 hours is a significant predictor of death in patients with a high LAS.
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A single center study from the US found that IPF patients with high LAS (≥50) had significantly poorer one year survival (65.1%) compared to IPF patients with low LAS (<50) (79.9%).
“A single center study from the US also found that IPF patients with a high LAS (≥50) had significantly (P = 0.013) poorer one year survival (65.1%) compared to IPF patients with a low-LAS (<50) (79.9%) [72].”
From Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature (2014) · cites this paper as [72]
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Impact of U.S. Lung Allocation Score on Survival After Lung Transplantation
Merlo, C. A., Weiss, E. S., Orens, J. B., Borja, M. C., Diener-West, M., Conte, J. V., & Shah, A. S. (2009) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2009.04.024 · Cited by 144
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Research works printed but not linked: 15
- Christie, 2009, The registry of the International Society of the Heart and Lung Transplantation: twenty-sixth official adult lung and heart-lung transplantation report – 2009, J Heart Lung Transplant, 28, 1031, 10.1016/j.healun.2009.08.004 · DOI
- Titman, 2009, Disease-specific survival benefit of lung transplantation in adults: a national cohort study, Am J Transplant, 9, 1640, 10.1111/j.1600-6143.2009.02613.x · DOI · Paper page
- Levine, 2006, Analytical methods and database design: implications for transplant researchers, 2005, Am J Transplant, 6, 1228, 10.1111/j.1600-6143.2006.01277.x · DOI
- Egan, 2006, Development of new lung allocation system in the United States, Am J Transplant, 6, 1212, 10.1111/j.1600-6143.2006.01276.x · DOI · Paper page
- Hachem, 2008, The new lung allocation system and its impact on waiting list characteristics and post-transplant outcomes, Semin Thorac Cardiovasc Surg, 20, 139, 10.1053/j.semtcvs.2008.04.004 · DOI
- Kozower, 2008, The impact of the lung allocation core on short-term transplantation outcomes: a multicenter study, J Thorac Cardiovasc Surg, 135, 166, 10.1016/j.jtcvs.2007.08.044 · DOI
- Osaki, 2009, The impact of the lung allocation scoring system at the single National Veterans Affairs Hospital lung transplantation program, Eur J Cardiothorac Surg, 36, 497, 10.1016/j.ejcts.2009.03.013 · DOI
- Weiss, 2009, Lung allocation score predicts survival in lung transplantation patients with pulmonary fibrosis, Ann Thorac Surg Thorac, 88, 1757, 10.1016/j.athoracsur.2009.07.005 · DOI
- Russo, 2010, High lung allocation score is associated with increased morbidity and mortality following transplantation, Chest, 137, 651, 10.1378/chest.09-0319 · DOI
- Liu, 2010, Increasing lung allocation scores predict worsened survival among lung transplant recipients, Am J Transplant, 10, 915, 10.1111/j.1600-6143.2009.03003.x · DOI
- Arnaoutalis, 2011, Impact of the lung allocation score on resource utilization after lung transplantation in the United States, J Heart Lung Ttansplant, 30, 14, 10.1016/j.healun.2010.06.018 · DOI
- Yusen, 2010, Lung transplantation in the United States, 1999-2008, Am J Transplant, 10, 1047, 10.1111/j.1600-6143.2010.03055.x · DOI
- Thabut, 2005, Graft ischemic time and outcome of lung transplantation: a multicenter analysis, Am J Respir Crit Care Med, 171, 786, 10.1164/rccm.200409-1248OC · DOI
- Gammie, 1999, Effect of ischemic time on survival in clinical lung transplantation, Ann Thorac Surg, 68, 2015, 10.1016/S0003-4975(99)00903-0 · DOI
- Russo, 2009, Who is the high-risk recipient?, J Thorac Cardiovasc Surg, 138, 1234, 10.1016/j.jtcvs.2009.07.036 · DOI
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Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature
Kistler, K. D., Nalysnyk, L., Rotella, P., & Esser, D. (2014) · BMC Pulmonary Medicine · doi:10.1186/1471-2466-14-139 · Cited by 151
“9%) [72].”
Metadata
- Authors
- Horai, T., Shigemura, N., Gries, C., Pilewski, J., Bhama, J. K., Bermudez, C. A., Zaldonis, D., & Toyoda, Y.
- Affiliations
- University of Pittsburgh Medical Center (US)
- Corresponding author
- Toyoda, Yoshiya
- Venue
- The Annals of Thoracic Surgery
- Publisher
- Elsevier BV
- Published
- 2012-05
- Volume
- 93
- Issue
- 5
- Pages
- 1592-1597
- ISSN
- 0003-4975 (ISSN-L)
- OpenAlex
- W2060708132
- Cited by
- 32
- References
- 1
- Citations by year
- 2026: 1 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 4 · 2015: 3 · 2014: 3 · 2013: 6 · 2012: 2
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Annals of Thoracic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Organ Donation and Transplantation
- Keywords
- lung transplantation, lung allocation score, postoperative mortality, ischemic time, ventilator support, ICU length of stay, tracheostomy, mortality risk factors
- MeSH terms
- Adult, Aged, Analysis of Variance, Cystic Fibrosis, Education, Medical, Continuing, Female, Follow-Up Studies, Graft Rejection, Graft Survival, Humans, Male, Middle Aged, Tissue and Organ Procurement, Pulmonary Fibrosis, Regression Analysis, Retrospective Studies, Time Factors, Tissue Donors, Ultrasonography, Waiting Lists, Cohort Studies, Multivariate Analysis, Proportional Hazards Models, Survival Analysis, Lung Transplantation, Treatment Outcome, Risk Assessment, Pulmonary Disease, Chronic Obstructive, Kaplan-Meier Estimate
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