The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.
Postoperative Atrial Fibrillation Significantly Increases Mortality, Hospital Readmission, and Hospital Costs
Open accessAbstract
Background New-onset postoperative atrial fibrillation (POAF) is the most common complication following cardiac surgery. However, the magnitude of POAF on length of stay, resource utilization, and readmission rates remains an area of clinical interest. The purpose of this study was to examine the risk-adjusted impact of POAF on measures of mortality, hospital resources, and costs among multiple centers.Methods A total of 49,264 patient records from a multi-institutional Society of Thoracic Surgeons (STS) certified database for cardiac operations (2001 to 2012) were extracted and stratified by the presence of POAF (19%) versus non-POAF (81%). The influence of POAF on outcomes was assessed by hierarchic regression modeling, adjusted for calculated STS predictive risk indices.Results Mean age was 64±11 years, and median STS predicted risk of mortality for patients who developed POAF were incrementally higher (2% vs 1%, p<0.001) compared with non-POAF patients. The rate of POAF was highest among those undergoing aortic valve replacement+coronary artery bypass grafting, aortic valve, and mitral valve replacement operations. The POAF patients had a higher unadjusted incidence of mortality, morbidity, hospital readmission, longer intensive care unit (ICU) and postoperative length of stay, and higher hospital costs. After risk adjustment, POAF was associated with a twofold increase in the odds of mortality (adjusted odds ratio=2.04, p<0.001), greater hospital resource utilization, and increased costs; POAF was associated with 48 additional ICU hours (p<0.001), 3 additional hospital days (p<0.001), and $3,000 (p<0.001) and $9,000 (p<0.001) of increased ICU and total hospital-related costs, respectively.Conclusions New onset POAF is associated with increased risk-adjusted mortality, hospital costs, and readmission rates. Protocols to reduce the incidence of POAF have the potential to significantly impact patient outcomes and the delivery of high-quality, cost-effective patient care.
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“Postoperative AF is associated with an increased early stroke risk, increased morbidity, and 30-day mortality.927,951,952”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [951]
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A multicenter risk index for atrial fibrillation after cardiac surgery
Mathew, J. P. (2004) · JAMA · doi:10.1001/jama.291.14.1720 · Cited by 1,234
Predictors of Atrial Fibrillation After Coronary Artery Surgery
Aranki, S. F., Shaw, D. P., Adams, D. H., Rizzo, R. J., Couper, G. S., VanderVliet, M., Collins, J. J., Cohn, L. H., & Burstin, H. R. (1996) · Circulation · doi:10.1161/01.cir.94.3.390 · Cited by 1,180
Hazards of postoperative atrial arrhythmias
Creswell, L. L., Schuessler, R. B., Rosenbloom, M., & Cox, J. L. (1993) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(93)90894-n · Cited by 995
Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery
Mathew, J. P. (1996) · JAMA · doi:10.1001/jama.276.4.300 · Cited by 806
Postoperative atrial fibrillation and mortality after coronary artery bypass surgery
Villareal, R. P., Hariharan, R., Liu, B. C., Kar, B., Lee, V.-V., Elayda, M., Lopez, J. A., Rasekh, A., Wilson, J. M., & Massumi, A. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.11.023 · Cited by 715
Atrial Fibrillation After Cardiac Surgery
Almassi, G. H., Schowalter, T., Nicolosi, A. C., Aggarwal, A., MORITZ, T. E., Henderson, W. G., Tarazi, R. Y., Shroyer, A. L., Sethi, G. K., Grover, F. L., et al. (1997) · Annals of Surgery · doi:10.1097/00000658-199710000-00011 · Cited by 711
LaPar, D. J., Crosby, I. K., Ailawadi, G., Ad, N., Choi, E., Spiess, B. D., Rich, J. B., Kasirajan, V., Fonner, E., Kron, I. L., et al. (2013) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2012.12.041 · Cited by 196
Prophylaxis of atrial fibrillation with magnesium sulfate after coronary artery bypass grafting
Fanning, W. J., Thomas, C. S., Roach, A. C., Tomichek, R. C., Alford, W. C., & Stoney, W. S. (1991) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(91)90918-g · Cited by 189
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2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403
2018 ESC/EACTS Guidelines on myocardial revascularization
Neumann, F., Sousa‐Uva, M., Ahlsson, A., Alfonso, F., BANNING, A. P., Benedetto, U., Byrne, R. A., Collet, J., Falk, V., Head, S. J., et al. (2019) · EuroIntervention · doi:10.4244/eijy19m01_01 · Cited by 1,278
Metadata
- Authors
- LaPar, D. J., Speir, A. M., Crosby, I. K., Fonner, E., Brown, M., Rich, J. B., Quader, M., Kern, J. A., Kron, I. L., & Ailawadi, G.
- Affiliations
- University of Virginia (US)
- Inova Health System (US)
- Mary Washington Hospital (US)
- Sentara Heart Hospital (US)
- Virginia Commonwealth University Medical Center (US)
- Corresponding author
- Ailawadi, Gorav
- Venue
- The Annals of Thoracic Surgery
- Publisher
- Elsevier BV
- Published
- 2014-08
- Volume
- 98
- Issue
- 2
- Pages
- 527-533
- ISSN
- 0003-4975 (ISSN-L)
- OpenAlex
- W2069608457
- Cited by
- 285
- References
- 23
- Citations by year
- 2026: 16 · 2025: 25 · 2024: 23 · 2023: 27 · 2022: 34 · 2021: 27 · 2020: 23 · 2019: 25 · 2018: 28 · 2017: 28 · 2016: 16 · 2015: 12 · 2014: 1
- FWCI
- 13.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Annals of Thoracic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Keywords
- postoperative atrial fibrillation, cardiac surgery complications, mortality, hospital readmission, hospital costs, length of hospital stay, intensive care utilization, aortic valve replacement, mitral valve replacement, coronary artery bypass grafting, risk adjustment
- MeSH terms
- Aged, Atrial Fibrillation, Female, Cardiac Surgical Procedures, Humans, Male, Middle Aged, Patient Readmission, Postoperative Complications, Retrospective Studies, Hospital Costs, Risk Adjustment
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