The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Fatigue in systemic lupus erythematosus: An association with reduced physical fitness
Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by fatigue; however, little research has been performed to identify non-pharmacological strategies, such as physical exercise, that can be employed in the prevention and treatment of fatigue in patients with SLE. Moreover, it is not clear whether physical fitness (defined here as cardiovascular fitness and muscle strength) and functional capacities are related to SLE-associated fatigue. Here, we review the studies, mechanisms and results that relate to SLE-associated fatigue. The main findings indicate that SLE patients have lower cardiovascular capacity than healthy subjects. Physical fitness, muscle strength and functional capacity are also lower in patients with SLE than in healthy individuals. The effects of exercise programs in reducing symptoms of fatigue in SLE patients remain unclear.
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“For instance, fatigue in SLE has been directly associated with reduced physical fitness, suggesting a target for tailored exercise interventions [95].”
From Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation (2025) · cites this paper as [95]
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Cites
The 1982 revised criteria for the classification of systemic lupus erythematosus
Tan, E. M., Cohen, A. S., Fries, J. F., Masi, A. T., Mcshane, D. J., Rothfield, N. F., Schaller, J. G., Talal, N., & Winchester, R. J. (1982) · Arthritis & Rheumatism · doi:10.1002/art.1780251101 · Cited by 14,519
Hochberg, M. C. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1780400928 · Cited by 11,409
Progression Models in Resistance Training for Healthy Adults
(2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181915670 · Cited by 4,332
Immunological aspects of chronic fatigue syndrome
Lorusso, L., Mikhaylova, S. V., Capelli, E., Ferrari, D., Ngonga, G. K., & Ricevuti, G. (2009) · Autoimmunity Reviews · doi:10.1016/j.autrev.2008.08.003 · Cited by 277
A study of fatigue in systemic lupus erythematosus.
Krupp, L., LaRocca, N. G., Muir, J., & Steinberg, A. D. (1990) · PubMed · Cited by 209
Fatigue in systemic lupus erythematosus: a randomized controlled trial of exercise
Tench, C. M. (2003) · Rheumatology · doi:10.1093/rheumatology/keg289 · Cited by 200
Opava, C. H. (2000) · Scandinavian Journal of Rheumatology · doi:10.1080/030097400447679 · Cited by 155
de Carvalho, M. R. P., Sato, E. I., Tebexreni, A. S., Heidecher, R. T. C., Schenkman, S., & Neto, T. L. B. (2005) · Arthritis Care & Research · doi:10.1002/art.21605 · Cited by 141
EFFECTS OF AEROBIC CONDITIONING IN LUPUS FATIGUE: A PILOT STUDY
ROBB-NICHOLSON, L. C., Daltroy, L. H., Eaton, H. M., Gall, V., WRIGHT, E., Hartley, L. H., Schur, P. H., & Liang, M. H. (1989) · Lara D. Veeken · doi:10.1093/rheumatology/28.6.500 · Cited by 138
Aerobic fitness, fatigue, and physical disability in systemic lupus erythematosus.
Tench, C. M., Bentley, D. J., Vleck, V. E., McCurdie, I. M., White, P. D., & D’Cruz, D. P. (2002) · PubMed · Cited by 134
Research works printed but not linked: 2
- Balsamo, 2010, Higher fatigue less muscle strength in women with systemic lupus erythematosus, 18(4), 356
- Balsamo, 2010, Functional capacity, physical fitness and fatigue in women with systemic lupus erythematosus, vol. 50, 182
Cited by
Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation
Nunez, S. G., Rabelo, S. P., Subotic, N., Caruso, J. W., & Knezevic, N. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26209994 · Cited by 138
“For instance, fatigue in SLE has been directly associated with reduced physical fitness, suggesting a target for tailored exercise interventions [95].”
Metadata
- Authors
- Balsamo, S., & Santos-Neto, L. D.
- Venue
- Autoimmunity Reviews
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 10
- Issue
- 9
- Pages
- 514-518
- ISSN
- 1568-9972 (ISSN-L)
- OpenAlex
- W1988996808
- Cited by
- 47
- References
- 31
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 4 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 7 · 2012: 2
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Autoimmunity Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- systemic lupus erythematosus, fatigue, physical fitness, cardiorespiratory fitness, muscle strength, functional capacity, exercise therapy, autoimmune disease
- MeSH terms
- Cardiovascular System, Fatigue, Humans, Lupus Erythematosus, Systemic, Physical Fitness, Risk Factors, Exercise, Muscle Strength
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- Balsamo, S., & Santos-Neto, L. D. (2011). Fatigue in systemic lupus erythematosus: An association with reduced physical fitness. Autoimmunity Reviews. https://doi.org/10.1016/j.autrev.2011.03.005
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.