The DOI matches its Crossref record; 132 of the 132 references it cites were found in a registry or an index.
Neutrophil extracellular traps (NETs) in autoimmune diseases: A comprehensive review
Open accessAbstract
Neutrophil extracellular traps (NETs) are fibrous networks which protrude from the membranes of activated neutrophils. NETs are found in a variety of conditions such as infection, malignancy, atherosclerosis, and autoimmune diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV), psoriasis, and gout. Studies suggest that an imbalance between "NETosis," which is a process by which NETs are formed, and NET degradation may be associated with autoimmune diseases. Neutrophils, interleukin-8, ANCA and other inflammatory molecules are considered to play a key role in NET formation. Prolonged exposure to NETs-related cascades is associated with autoimmunity and increases the chance of systemic organ damage. In this review, we discuss the roles of various inflammatory molecules in relation to NETs. We also describe the role of NETs in the pathogenesis of autoimmune diseases and discuss the possibility of using targeted therapies directed to NETs and associated molecules to treat autoimmune diseases.
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Cites
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Cited by
Kell, D. B., Heyden, E. L., & Pretorius, E. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01221 · Cited by 460
Barrera, M.-J., Aguilera, S., Castro, I., Carvajal, P., Jara, D., Molina, C., González, S., & González, M.-J. (2021) · Autoimmunity Reviews · doi:10.1016/j.autrev.2021.102867 · Cited by 213
Toll-like receptor 4: A potential therapeutic target for multiple human diseases
Wei, J., Zhang, Y., Li, H., Wang, F., & Yao, S. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115338 · Cited by 121
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Aging hampers neutrophil extracellular traps (NETs) efficacy
Sabbatini, M., Bona, E., Novello, G., Migliario, M., & Renò, F. (2022) · Aging Clinical and Experimental Research · doi:10.1007/s40520-022-02201-0 · Cited by 51
Metadata
- Authors
- Lee, K. H., Kronbichler, A., Park, D. D.-Y., Park, Y., Moon, H., Kim, H., Choi, J. H., Choi, Y., Shim, S., Lyu, I. S., Yun, B. H., Han, Y., Lee, D., Lee, S. Y., Yoo, B. H., Lee, K. H., Kim, T. L., Kim, H., Shim, J. S., Nam, W., So, H., Choi, S., Lee, S., & Shin, J. I.
- Venue
- Autoimmunity Reviews
- Publisher
- Elsevier BV
- Published
- 2017-11
- Volume
- 16
- Issue
- 11
- Pages
- 1160-1173
- ISSN
- 1568-9972 (ISSN-L)
- OpenAlex
- W2753229994
- Cited by
- 624
- References
- 132
- FWCI
- 14.44
- Type
- journal article
- Language
- en
- Open access
- green
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- Lee, K. H., Kronbichler, A., Park, D. D.-Y., Park, Y., Moon, H., Kim, H., Choi, J. H., Choi, Y., Shim, S., Lyu, I. S., Yun, B. H., Han, Y., Lee, D., Lee, S. Y., Yoo, B. H., Lee, K. H., Kim, T. L., Kim, H., Shim, J. S., . . . Shin, J. I. (2017). Neutrophil extracellular traps (NETs) in autoimmune diseases: A comprehensive review. Autoimmunity Reviews. https://doi.org/10.1016/j.autrev.2017.09.012
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
