Vimentin as antigenic target in autoimmunity: A comprehensive review

Vimentin in cancer and its potential as a molecular target for cancer therapy

Satelli, A., & Li, S. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0735-1 · Cited by 1,557

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

Fuchs, E. V., & Weber, K. (1994) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.63.070194.002021 · Cited by 1,427

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

Khandpur, R., Carmona‐Rivera, C., Vivekanandan‐Giri, A., Gizinski, A. M., Yalavarthi, S., Knight, J. S., Friday, S. C., Li, S., Patel, R. M., Subramanian, V., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005580 · Cited by 1,374

Sarcoidosis

Valeyre, D., Prasse, A., Nunes, H., Uzunhan, Y., Brillet, P.-Y., & Müller-Quernheim, J. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60680-7 · Cited by 1,087

Novel functions of vimentin in cell adhesion, migration, and signaling

Ivaska, J., Pallari, H., Nevo, J., & Eriksson, J. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.03.040 · Cited by 786

Intermediate filaments: from cell architecture to nanomechanics

Herrmann, H. O., Bär, H., Kreplak, L., Strelkov, S. V., & Aebi, U. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2197 · Cited by 742

Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II Molecule

Hill, J. A., Southwood, S., Sette, A., Jevnikar, A. M., Bell, D., & Cairns, E. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.2.538 · Cited by 711

The multifactorial role of neutrophils in rheumatoid arthritis

Wright, H. L., Moots, R. J., & Edwards, S. W. (2014) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2014.80 · Cited by 602

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

Shi, J., Knevel, R., Suwannalai, P., van der Linden, M. P. M., Janssen, G. M. C., van Veelen, P. A., Levarht, N. E. W., Mil, A. H. M. V. D. H., Cerami, A., Huizinga, T. W. J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114465108 · Cited by 595

Aggregatibacter actinomycetemcomitans –induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

Konig, M. F., Abusleme, L., Reinholdt, J., Palmer, R. J., Jr., Teles, R. P., Sampson, K., Rosen, A., Nigrovic, P. A., Sokolove, J. B., Giles, J. T., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaj1921 · Cited by 592

Post-translational modifications of intermediate filament proteins: mechanisms and functions

Snider, N. T., & Omary, M. B. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3753 · Cited by 557

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

Makrygiannakis, D., Hermansson, M., Ulfgren, A.-K., Nicholas, A. P., Zendman, A. J. W., Eklúnd, A., Grünewald, J., Sköld, C. M., Klareskog, L., & Catrina, A. I. (2008) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2007.075192 · Cited by 550

Vimentin is secreted by activated macrophages

Mor-Vaknin, N., Punturieri, A., Sitwala, K., & Markovitz, D. M. (2003) · Nature Cell Biology · doi:10.1038/ncb898 · Cited by 522

Vimentin function in lymphocyte adhesion and transcellular migration

Nieminen, M., Henttinen, T. A., Karikoski, M., Marttila‐Ichihara, F., Eriksson, J., & Jalkanen, S. (2006) · Nature Cell Biology · doi:10.1038/ncb1355 · Cited by 467

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

Vossenaar, E. R., Després, N., Lapointe, E., van der Heijden, A., Lora, M., Senshu, T., VENROOIJ, W. J. V., & Ménard, H. A. (2004) · Arthritis Research & Therapy · doi:10.1186/ar1149 · Cited by 463

Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages

Vossenaar, E. R., Radstake, T. R. D. J., van der Heijden, A., van Mansum, M. A. M., Dieteren, C., de Rooij, D.-J., Barrera, P., Zendman, A. J. W., & van Venrooij, W. J. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2003.012211 · Cited by 454

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

Scally, S. W., Petersen, J., Law, S. C., Dudek, N. L., Nel, H. J., Loh, K. L., Wijeyewickrema, L. C., Eckle, S. B. G., van Heemst, J., Pike, R. N., et al. (2013) · Journal of Experimental Medicine · doi:10.1084/jem.20131241 · Cited by 429

Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

Mitroulis, I., Kambas, K., Chrysanthopoulou, A., Skendros, P., Apostolidou, E., Kourtzelis, I., Drosos, G. I., Boumpas, D. T., & Ritis, K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0029318 · Cited by 387

Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis

Mohan, C., & Putterman, C. (2015) · Nature Reviews Nephrology · doi:10.1038/nrneph.2015.33 · Cited by 376

In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

Chang, A., Henderson, S., Brandt, D. R., Liu, N., Guttikonda, R., Hsieh, C., Kaverina, N., Utset, T. O., Meehan, S. M., Quigg, R. J., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001983 · Cited by 364

Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments

Eriksson, J. E., He, T., Trejo-Skalli, A. V., Härmälä-Braskén, A.-S., Hellman, J., Chou, Y.-H., & Goldman, R. D. (2004) · Journal of Cell Science · doi:10.1242/jcs.00906 · Cited by 336

The role of autoantibodies in the pathophysiology of rheumatoid arthritis

Derksen, V. F. A. M., Huizinga, T. W. J., & van der Woude, D. (2017) · Seminars in Immunopathology · doi:10.1007/s00281-017-0627-z · Cited by 330

Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid arthritis

Bang, H., Egerer, K., Gauliard, A., Lüthke, K., Rudolph, P. E., Fredenhagen, G., Berg, W., Feist, E., & Burmester, G. R. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22817 · Cited by 291

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

Hill, J. A., Bell, D., Brintnell, W. C., Yue, D., Wehrli, B. M., Jevnikar, A. M., Lee, D. M., Hueber, W., Robinson, W. H., & Cairns, E. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072051 · Cited by 275

Intermediate filaments are dynamic and motile elements of cellular architecture

Helfand, B. T., Chang, L., & Goldman, R. D. (2003) · Journal of Cell Science · doi:10.1242/jcs.00936 · Cited by 259

Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

Klareskog, L., Malmström, V., Lundberg, K., Padyukov, L., & Alfredsson, L. S. (2011) · Seminars in Immunology · doi:10.1016/j.smim.2011.01.014 · Cited by 254

Endothelial–mesenchymal transition and its contribution to the emergence of stem cell phenotype

Medici, D., & Kalluri, R. (2012) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2012.04.004 · Cited by 250

Vimentin is a novel AKT1 target mediating motility and invasion

Qs, Z., Rosenblatt, K. P., Huang, K.-L., Lahat, G., Brobey, R. K. B., Bolshakov, S. V., Nguyen, T. T., Ding, Z., Belousov, R., Bill, K., et al. (2010) · Oncogene · doi:10.1038/onc.2010.421 · Cited by 247

Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn’s disease

Kirkegaard, T., Hansen, A., Bruun, E., & Brynskov, J. (2004) · Gut · doi:10.1136/gut.2003.017442 · Cited by 222

The rheumatoid arthritis HLA–DRB1 shared epitope

Holoshitz, J. (2010) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e328336ba63 · Cited by 213

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis

Quirke, A., Lugli, E. B., Wegner, N., Hamilton, B. C., Charles, P. J., Chowdhury, M., Ytterberg, A. J., Zubarev, R. A., Potempa, J., Culshaw, S., et al. (2013) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2012-202726 · Cited by 207

Aurora-B Regulates the Cleavage Furrow-specific Vimentin Phosphorylation in the Cytokinetic Process

Goto, H., Yasui, Y., Kawajiri, A., Nigg, E. A., Terada, Y., Tatsuka, M., Nagata, K., & Inagaki, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210892200 · Cited by 205

A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)

Leeming, D. J., He, Y., Veidal, S., Nguyen, Q., Larsen, D., Koizumi, M., Segovia‐Silvestre, T., Zhang, C., Zheng, Q., Sun, S., et al. (2011) · Biomarkers · doi:10.3109/1354750x.2011.620628 · Cited by 185

Vimentin Expressed on Mycobacterium tuberculosis -Infected Human Monocytes Is Involved in Binding to the NKp46 Receptor

Garg, A., Barnes, P. F., Porgador, A., Roy, S., Wu, S., Nanda, J. S., Griffith, D. E., Girard, W. M., Rawal, N., Shetty, S., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.9.6192 · Cited by 182

The Sa system: a novel antigen-antibody system specific for rheumatoid arthritis.

Després, N., Boire, G., López-Longo, F. J., & Ménard, H. A. (1994) · PubMed · Cited by 181

Vimentin as an Integral Regulator of Cell Adhesion and Endothelial Sprouting

Dave, J. M., & Bayless, K. J. (2014) · Microcirculation · doi:10.1111/micc.12111 · Cited by 179

Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis

Juárez, M., Bang, H., Hammar, F., Reimer, U., Dyke, B., Sahbudin, I., Buckley, C. D., Fisher, B. A., Filer, A. D., & Raza, K. (2015) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2014-206785 · Cited by 175

Diagnostic tests for rheumatoid arthritis: comparison of anti-cyclic citrullinated peptide antibodies, anti-keratin antibodies and IgM rheumatoid factors

Bas, S. (2002) · British journal of rheumatology · doi:10.1093/rheumatology/41.7.809 · Cited by 171

Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies

André-Schwartz, J., Datta, S. K., Shoenfeld, Y., Isenberg, D. A., Stollar, B. D., & Schwartz, R. S. (1984) · Clinical Immunology and Immunopathology · doi:10.1016/0090-1229(84)90246-0 · Cited by 170

Plasma B Lymphocyte Stimulator and B Cell Differentiation in Idiopathic Pulmonary Fibrosis Patients

Xue, J., Kass, D. J., Bon, J. M., Vuga, L. J., Tan, J., Csizmadia, E., Otterbein, L. E., Soejima, M., Levesque, M. C., Gibson, K. F., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203476 · Cited by 165

A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization

Helfand, B. T., Mikami, A., Vallee, R. B., & Goldman, R. D. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202027 · Cited by 164

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies

Jiang, X., Trouw, L. A., van Wesemael, T. J., Shi, J., Bengtsson, C., Källberg, H., Malmström, V., Israelsson, L., Hreggvidsdottir, H. S., Verduijn, W., et al. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-205109 · Cited by 157

Cell surface expression of intermediate filament proteins vimentin and lamin B1 in human neutrophil spontaneous apoptosis

Moisan, É., & Girard, D. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0405190 · Cited by 156

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

Lundberg, K., Bengtsson, C., Kharlamova, N., Reed, E., Jiang, X., Källberg, H., Dorocic, I. P., Israelsson, L., Kessel, C., Padyukov, L., et al. (2012) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2012-201484 · Cited by 155

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation

Ytterberg, A. J., Joshua, V., Reynisdottir, G., Tarasova, N. K., Rutishauser, D., Ossipova, E., Hensvold, A. H., Eklúnd, A., Sköld, C. M., Grünewald, J., et al. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-204912 · Cited by 149

Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA–DRB1 shared epitope, regardless of rheumatoid factor or anti–cyclic citrullinated peptide antibody status

Bang, S., Lee, K. H., Cho, S., Lee, H., Lee, K. W., & Bae, S. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27272 · Cited by 146

Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

Lugli, E. B., Correia, R. E., Fischer, R., Lundberg, K., Bracke, K. R., Montgomery, A. B., Kessler, B. M., Brusselle, G., & Venables, P. J. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0520-x · Cited by 134

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis–specific humoral autoimmunity

Rycke, L. D., Nicholas, A. P., Cantaert, T., Kruithof, E., Echols, J. D., Vandekerckhove, B., VEYS, E. M., Keyser, F. D., & Baeten, D. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21220 · Cited by 130

Biological markers in inflammatory bowel disease: Practical consideration for clinicians

Mendoza, J. L., & Abreu, M. T. (2009) · Gastroentérologie Clinique et Biologique · doi:10.1016/s0399-8320(09)73151-3 · Cited by 128

Fine specificity of the anti–citrullinated protein antibody response is influenced by the shared epitope alleles

Verpoort, K. N., Cheung, K., Ioan‐Facsinay, A., Mil, A. H. M. V. D. H., Vries-Bouwstra, J. K. D., Allaart, C. F., Drijfhout, J. W., de Vries, R. R. P., Breedveld, F. C., Huizinga, T. W. J., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.23127 · Cited by 127

Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface

Podor, T. J., Singh, D., Chindemi, P. A., Foulon, D. M., McKelvie, R. S., Weitz, J. I., Austin, R. C., Boudreau, G., & Davies, R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109675200 · Cited by 126

Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

van Steendam, K., Tilleman, K., Ceuleneer, M. D., Keyser, F. D., Elewaut, D., & Deforce, D. (2010) · Arthritis Research & Therapy · doi:10.1186/ar3070 · Cited by 119

Phosphorylation and reorganization of vimentin by p21‐activated kinase (PAK)

Goto, H., Tanabe, K., Manser, E. J., Lim, L., Yasui, Y., & Inagaki, M. (2002) · Genes to Cells · doi:10.1046/j.1356-9597.2001.00504.x · Cited by 118

Immunologic characteristics of intrarenal T cells: Trafficking of expanded CD8+ T cell β‐chain clonotypes in progressive lupus nephritis

WINCHESTER, R. J., Wiesendanger, M., Zhang, H., Steshenko, V., Peterson, K. S., Geraldino-Pardilla, L. B., Ruiz-Vazquez, E. M., & D’Agati, V. D. (2011) · Arthritis & Rheumatism · doi:10.1002/art.33488 · Cited by 117

Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2

Boilard, É., Bourgoin, S. G., Bernatchez, C., & Surette, M. E. (2003) · Blood · doi:10.1182/blood-2002-12-3702 · Cited by 111

Glomerular Autoimmune Multicomponents of Human Lupus Nephritis In Vivo

Bruschi, M., Sinico, R. A., Moroni, G. L., Pratesi, F., Migliorini, P., Galetti, M., Murtas, C., Tincani, A., Madaio, M. P., Radice, A., et al. (2014) · Journal of the American Society of Nephrology · doi:10.1681/asn.2013090987 · Cited by 110

Influence of HLA–DR genes on the production of rheumatoid arthritis–specific autoantibodies to citrullinated fibrinogen

Auger, I., Sebbag, M., Vincent, C., Balandraud, N., Guis, S., Nogueira, L., Svensson, B., Cantagrel, A. G., Serre, G., & Roudier, J. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21391 · Cited by 106

The lung in ACPA-positive rheumatoid arthritis: an initiating site of injury?

Perry, E. S., Kelly, C. A., Eggleton, P., Soyza, A. D., & Hutchinson, D. G. (2014) · Rheumatology · doi:10.1093/rheumatology/keu195 · Cited by 103

Vimentin Is a Dominant Target of In Situ Humoral Immunity in Human Lupus Tubulointerstitial Nephritis

Kinloch, A. J., Chang, A., Ko, K., Henry, C., Henderson, S., Maienschein‐Cline, M., Kaverina, N. V., Rovin, B. H., Ferrer, M. S., Wolfgeher, D., et al. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38888 · Cited by 101

Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome

Ortona, E., Capozzi, A., Colasanti, T., Conti, F., Alessandri, C., Longo, A., Garofalo, T., Margutti, P., Misasi, R., Khamashta, M. A., et al. (2010) · Blood · doi:10.1182/blood-2010-04-279208 · Cited by 99

Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis

Burska, A. N., Hunt, L. H., Boissinot, M., Strollo, R., Ryan, B. J., Vital, E. M. J., Nissim, A., Winyard, P. G., Emery, P., & Ponchel, F. (2014) · Mediators of Inflammation · doi:10.1155/2014/492873 · Cited by 94

The Pathogenesis and Therapeutic Implications of Tubulointerstitial Inflammation in Human Lupus Nephritis

Clark, M. R., Trotter, K. C., & Chang, A. (2015) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2015.08.007 · Cited by 91

Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn’s Disease from Ulcerative Colitis

Mortensen, J. H., Godskesen, L. E., Jensen, M. D., van Haaften, W. T., Klinge, L. G., Olinga, P., Dijkstra, G. D. H., Kjeldsen, J., Karsdal, M. A., Bay‐Jensen, A., et al. (2015) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjv123 · Cited by 86

Autoimmunity to vimentin is associated with outcomes of patients with idiopathic pulmonary fibrosis

Li, F. J., Surolia, R., Li, H., Wang, Z., Kulkarni, T., Liu, G., de Andrade, J. A., Kass, D. J., Thannickal, V. J., Duncan, S. R., et al. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700473 · Cited by 85

Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis

Ospelt, C., Bang, H., Feist, E., Camici, G. G., Keller, S., Detert, J., Krämer, A., Gay, S., Ghannam, K., & Burmester, G. R. (2017) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2016-210059 · Cited by 83

The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis

Steendam, K. V., Tilleman, K., & Deforce, D. L. D. (2011) · Lara D. Veeken · doi:10.1093/rheumatology/keq419 · Cited by 82

Dissecting the 3-D structure of vimentin intermediate filaments by cryo-electron tomography

Goldie, K. N., Wedig, T., MITRA, A. K., Aebi, U., Herrmann, H. O., & Hoenger, A. (2006) · Journal of Structural Biology · doi:10.1016/j.jsb.2006.12.007 · Cited by 82

Neutrophil Fate in Gingival Crevicular Fluid

Vitkov, L., Klappacher, M., Hannig, M., & Krautgartner, W. D. (2010) · Ultrastructural Pathology · doi:10.3109/01913120903419989 · Cited by 80

Electrostatic and hydrophobic interactions of the intermediate filament protein vimentin and its amino terminus with lipid bilayers.

Perides, G., Harter, C., & Traub, P. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76489-8 · Cited by 79

T-cell receptor–HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis

Grünewald, J., Kaiser, Y., Ostadkarampour, M., Rivera, N. V., Vezzi, F., Lötstedt, B., Olsen, R., Sylwan, L., Lundin, S., Käller, M., et al. (2015) · European Respiratory Journal · doi:10.1183/13993003.01209-2015 · Cited by 79

Lung T-Helper Cells Expressing T-cell Receptor AV2S3 Associate with Clinical Features of Pulmonary Sarcoidosis

Grünewald, J., Berlin, M., Olerup, O., & Eklúnd, A. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.3.9906001 · Cited by 78

The Sa system: a novel antigen-antibody system specific for rheumatoid arthritis.

Dagenais, P. (1995) · PubMed · Cited by 78

Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides

Tilleman, K., Steendam, K. V., Cantaert, T., Keyser, F. D., Elewaut, D. S., & Deforce, D. L. D. (2008) · Lara D. Veeken · doi:10.1093/rheumatology/ken077 · Cited by 76

Nucleases from Prevotella intermedia can degrade neutrophil extracellular traps

Doke, M., Fukamachi, H., Morisaki, H., Arimoto, T., Kataoka, H., & Kuwata, H. (2016) · Molecular Oral Microbiology · doi:10.1111/omi.12171 · Cited by 76

Soluble CD44 Interacts with Intermediate Filament Protein Vimentin on Endothelial Cell Surface

Päll, T., Pink, A., Kasak, L., Turkina, M., Anderson, W. R., Valkna, A., & Kogerman, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0029305 · Cited by 75

Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms

Andelid, K., Bake, B., Rak, S., Lindén, A., Rosengren, A., & Ekberg‐Jansson, A. (2006) · Respiratory Medicine · doi:10.1016/j.rmed.2006.09.023 · Cited by 75

Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology.

Vassiliadis, E., de Oliveira, C. P. M. S., Álvares‐da‐Silva, M. R., Zhang, C., Carrilho, F. J., Stefano, J. T., Rabelo, F., Pereira, L. M. M. B., Kappel, C., Henriksen, K., et al. (2012) · Europe PMC (PubMed Central) · Cited by 73

Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis

Wahlström, J., Dengjel, J., Winqvist, O., Targoff, I. N., Persson, B., Duyar, H., Rammensee, H., Eklúnd, A., Weissert, R., & Grünewald, J. (2009) · Clinical Immunology · doi:10.1016/j.clim.2009.08.008 · Cited by 69

Proteomic Profiling Reveals Autoimmune Targets in Sarcoidosis

Månberg, A., Hamsten, C., Wiklundh, E., Lindskog, C., Mattsson, C., Andersson, E., Lundberg, I. E., Grönlund, H., Schwenk, J. M., Eklúnd, A., et al. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201407-1341oc · Cited by 69

Circulating Citrullinated Vimentin Fragments Reflect Disease Burden in Ankylosing Spondylitis and Have Prognostic Capacity for Radiographic Progression

Bay‐Jensen, A., Karsdal, M. A., Vassiliadis, E., Wichuk, S. A., Marcher-Mikkelsen, K., Lories, R. J. U., Christiansen, C., & Maksymowych, W. P. (2012) · Arthritis & Rheumatism · doi:10.1002/art.37843 · Cited by 65

Murine Colitis is Mediated by Vimentin

Mor‐Vaknin, N., Legendre, M., Yu, Y., Serezani, C. H., Garg, S. K., Jatzek, A., Swanson, M. D., Gonzalez-Hernandez, M. J., Teitz‐Tennenbaum, S., Punturieri, A., et al. (2013) · Scientific Reports · doi:10.1038/srep01045 · Cited by 65

The Mosaic of “Seronegative” Antiphospholipid Syndrome

Conti, F., Capozzi, A., Truglia, S., Lococo, E., Longo, A., Misasi, R., Alessandri, C., Valesini, G., & Sorice, M. (2014) · Journal of Immunology Research · doi:10.1155/2014/389601 · Cited by 60

Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options

Gudmann, N. S., Hansen, N. U. B., Jensen, A. C. B., Karsdal, M. A., & Siebuhr, A. S. (2014) · Autoimmunity · doi:10.3109/08916934.2014.962024 · Cited by 57

A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice

Roland, B., Müller, M., Reuter, U., Herrmann, H. O., Büssow, H., & Magin, T. M. (2008) · Journal of Cell Science · doi:10.1242/jcs.030312 · Cited by 55

Innate immunity in the antiphospholipid syndrome: role of toll-like receptors in endothelial cell activation by antiphospholipid antibodies

Meroni, P. L., Raschi, E., Testoni, C., Parisio, A., & Borghi, M. O. (2004) · Autoimmunity Reviews · doi:10.1016/j.autrev.2004.07.007 · Cited by 55

Vimentin autoantibodies induce platelet activation and formation of platelet-leukocyte conjugates via platelet-activating factor

Leong, H. S., Mahesh, B., Day, J. R., Smith, J. D., McCormack, A., Ghimire, G., Podor, T. J., & Rose, M. L. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0607339 · Cited by 53

Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis

Eberhardt, C., Thillai, M., Parker, R., Siddiqui, N., Potiphar, L., Goldin, R. D., Timms, J. F., Wells, A. U., Kon, O. M., Wickremasinghe, M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0170285 · Cited by 52

RA autoantibodies as predictors of rheumatoid arthritis in non-cystic fibrosis bronchiectasis patients

Perry, E. S., Stenton, C., Kelly, C. A., Eggleton, P., Hutchinson, D. G., & Soyza, A. D. (2014) · European Respiratory Journal · doi:10.1183/09031936.00064014 · Cited by 50

Sumoylation of Vimentin354 Is Associated with PIAS3 Inhibition of Glioma Cell Migration

Wang, L., Zhang, J., Banerjee, S., Barnes, L., Sajja, V., Liu, Y., Guo, B., Du, Y., Agarwal, M. K., Wald, D. N., et al. (2010) · Oncotarget · doi:10.18632/oncotarget.196 · Cited by 46

Immunofluorescence microscopic demonstration of vimentin filaments in asteroid bodies of sarcoidosis

Cain, H., & Kraus, B. (1982) · Virchows Archiv B Cell Pathology Including Molecular Pathology · doi:10.1007/bf02890384 · Cited by 46

Orderly Pattern of Development of the Autoantibody Response in (New Zealand White × BXSB)F1 Lupus Mice: Characterization of Target Antigens and Antigen Spreading by Two-Dimensional Gel Electrophoresis and Mass Spectrometry

Thébault, S., Gilbert, D., Hubert, M., Drouot, L., Machour, N., Lange, C. M., Charlionet, R., & Tron, F. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.7.4046 · Cited by 44

The Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?

Goilav, B., & Putterman, C. (2015) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2015.08.005 · Cited by 43

Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens

Fernandes‐Cerqueira, C., Ossipova, E., Gunasekera, S., Hansson, M., Mathsson, L., Catrina, A. I., Sommarin, Y., Klareskog, L., Lundberg, K., Rönnelid, J., et al. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0666-6 · Cited by 40

Molecular and Biological Characterization of Streptococcal SpyA-mediated ADP-ribosylation of Intermediate Filament Protein Vimentin

Icenogle, L. M., Hengel, S. M., Coye, L. H., Streifel, A. C., Collins, C. M., Goodlett, D. R., & Moseley, S. L. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.370791 · Cited by 39

T‐cell phenotypes in bronchoalveolar lavage fluid, blood and lymph nodes in pulmonary sarcoidosis – indication for an airborne antigen as the triggering factor in sarcoidosis

Darlington, P., Olsen, H. H., von Sivers, K., Wahlström, J., Runold, M., Svjatoha, V., Porwit‐MacDonald, A., Eklúnd, A., & Grünewald, J. (2012) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2012.02543.x · Cited by 34

Anti-mutated citrullinated vimentin (anti-MCV) and anti-65kDa heat shock protein (anti-hsp65): New biomarkers in ankylosing spondylitis

Bodnár, N., Szekanecz, Z., Prohászka, Z., Kemény‐Beke, Á., Gyurcsik, Z. N., Gulyás, K., Lakos, G., Sipka, S., & Szántó, S. (2011) · Joint Bone Spine · doi:10.1016/j.jbspin.2011.03.010 · Cited by 30

Mutated citrullinated vimentin antibodies in rheumatoid arthritis

Kuna, A. T. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.10.020 · Cited by 28

Dynamic Expression of Peptidylarginine Deiminase 2 in Human Monocytic Leukaemia THP-1 Cells During Macrophage Differentiation

Hojo-Nakashima, I., Sato, R., Nakashima, K., Hagiwara, T., & YAMADA, M. (2009) · The Journal of Biochemistry · doi:10.1093/jb/mvp097 · Cited by 28

Carbamylated vimentin represents a relevant autoantigen in Latin American (Cuban) rheumatoid arthritis patients

Téllez, G. M., Gómez, J. A., Bang, H., Martinez‐Gamboa, L., Roggenbuck, D., Burmester, G. R., Torres, B., Hernández, D. M. P., & Feist, E. (2016) · Rheumatology International · doi:10.1007/s00296-016-3472-9 · Cited by 26

O-GlcNAc modification of radial glial vimentin filaments in the developing chick brain

FARACH, A. M., & Galileo, D. S. (2008) · Journal of Neurocytology · doi:10.1007/s11068-008-9036-5 · Cited by 23

Anti-mutated citrullinated vimentin antibodies in antiphospholipid syndrome: diagnostic value and relationship with clinical features

Alessandri, C., Agmon‐Levin, N., Conti, F., Perricone, C., Ortona, E., Pendolino, M., Capozzi, A., Delunardo, F., Mancini, R., Truglia, S., et al. (2017) · Immunologic Research · doi:10.1007/s12026-017-8899-x · Cited by 22

Specific antigen(s) in sarcoidosis: a link to autoimmunity?

Zissel, G., & Müller–Quernheim, J. (2016) · European Respiratory Journal · doi:10.1183/13993003.01791-2015 · Cited by 18

Vimentin dephosphorylation at ser-56 is regulated by type 1 protein phosphatase in smooth muscle

Li, J., Wang, R., & Tang, D. D. (2016) · Respiratory Research · doi:10.1186/s12931-016-0415-7 · Cited by 18

Meta-analysis: diagnostic value of serum anti-mutated citrullinated vimentin antibodies in patients with rheumatoid arthritis

Qin, X. Y., Deng, Y., Xu, J., Li, T., Li, S., & Zhao, J. (2010) · Rheumatology International · doi:10.1007/s00296-009-1343-3 · Cited by 17

Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis

Lindenberg, L., Spengler, L., Bang, H., Dörner, T., Maslyanskiy, А. L., Lapin, S. V., Ilivanova, E. I., Martinez‐Gamboa, L., Bastian, H., Wittenborn, E., et al. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0717-z · Cited by 16

Diagnostic value of the anti-Sa antibody compared with the anti-cyclic citrullinated peptide antibody in rheumatoid arthritis

Iwaszkiewicz, C., Puszczewicz, M., & Białkowska-Puszczewicz, G. (2014) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.12544 · Cited by 14

T cell receptor-Vβ repertoires in lung and blood CD4+ and CD8+T cells of pulmonary sarcoidosis patients

Ahlgren, K. M., Ruckdeschel, T., Eklúnd, A., Wahlström, J., & Grünewald, J. (2014) · BMC Pulmonary Medicine · doi:10.1186/1471-2466-14-50 · Cited by 14

Editorial: Autoimmunity to Vimentin and Lupus Nephritis

Davidson, A. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38885 · Cited by 12

Anti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis

Abedian, Z. (2015) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2015/14962.6456 · Cited by 7

Immunomodulatory effects of anti-tumor necrosis factor alpha therapy on synovium in spondylarthropathy: histologic findings in eight patients from an open-label pilot study

Warrington (2001) · Pure Amsterdam UMC · doi:10.1002/1529-0131(200101)44:1 · Cited by 2

Challenges of Sarcoidosis and Its Management

Drent, M., Crouser, E. D., & Grünewald, J. (2021) · New England Journal of Medicine · doi:10.1056/nejmra2101555 · Cited by 436

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Kasravi, M., Ahmadi, A., Babajani, A., Mazloomnejad, R., Hatamnejad, M. R., Shariatzadeh, S., Bahrami, S., & Niknejad, H. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00348-z · Cited by 316

Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral Infections

Ramos, I., Stamatakis, K., Oeste, C. L., & Pérez‐Sala, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134675 · Cited by 182

Glycolysis Rate-Limiting Enzymes: Novel Potential Regulators of Rheumatoid Arthritis Pathogenesis

Zuo, J., Tang, J., Lü, M., Zhou, Z., Li, Y., Tian, H., Liu, E., Gao, B., Liu, T., & Shao, P. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.779787 · Cited by 156

Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management

Pignatelli, P., Ettorre, E., Menichelli, D., Pani, A., Violi, F., & Pastori, D. (2020) · Haematologica · doi:10.3324/haematol.2019.221945 · Cited by 148

Antibodies against post-translationally modified vimentin peptides in patients with rheumatoid arthritis

Кузнецова, П. А., Maslyanskiy, А. L., Lapin, S. V., Маzing, A. V., Bang, H., & Vi, M. (2017) · Modern Rheumatology Journal · doi:10.14412/1996-7012-2017-3-44-49 · Cited by 2

Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides

Tilleman, K., Steendam, K. V., Cantaert, T., Keyser, F. D., Elewaut, D. S., & Deforce, D. L. D. (2008) · Lara D. Veeken · doi:10.1093/rheumatology/ken077 · Cited by 76

Identification and function of T cells reactive with citrullinated vimentin in HLA-DRB1*0401 humanised mice and rheumatoid arthritis patients

Snir, O., Rieck, M., Klich, K., Klareskog, L., Buckner, J. H., & Malmström, V. (2010) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2010.129668v

Mutated citrullinated vimentin antibodies in rheumatoid arthritis

Kuna, A. T. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.10.020 · Cited by 28

Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis

Ospelt, C., Bang, H., Feist, E., Camici, G. G., Keller, S., Detert, J., Krämer, A., Gay, S., Ghannam, K., & Burmester, G. R. (2017) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2016-210059 · Cited by 83