Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases
Andreadis, Athena·2005·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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Items 201–300 of 311
- Endoplasmic Reticulum Stress in Tauopathies: Contrasting Human Brain Pathology with Cellular and Animal ModelsNadia I. Bocai, María Silvina Marcora, Lautaro F. Belfiori-Carrasco, Laura Morelli, Eduardo Miguel Castaño · 2019 · Journal of Alzheimer s Disease
- The C291R Tau Variant Forms Different Types of ProtofibrilsThomas K. Karikari, Rachel Thomas, Kevin G. Moffat · 2020 · Frontiers in Molecular Neuroscience
- Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic miceYanchong Zhang, Feng Wu, Khalid Iqbal, Cheng‐Xin Gong, Wen Hui Hu, Fei Liu · 2019 · Scientific Reports
- SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathyJavier Andrés Muñiz, Carolina Lucía Facal, Leandro Urrutia, Ramiro Clerici-Delville, Ana Damianich, Juan Esteban Ferrario, Germán Falasco, María Elena Avale · 2022 · Frontiers in Bioengineering and Biotechnology
- Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3Daniel Ruiz-Gabarre, Laura Vallés‐Saiz, Almudena Carnero-Espejo, Isidró Ferrer, Félix Hernández, Ramón García‐Escudero, Jesús Ávila, Vega García‐Escudero · 2024 · EBioMedicine
- Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional BiochemistryThomas K. Karikari, Sophie Keeling, Emily Hill, Juan Lantero‐Rodriguez, David A. Nagel, Bruno Becker, Kina Höglund, Henrik Zetterberg, Kaj Blennow, Eric James Hill et al. · 2020 · ACS Chemical Neuroscience
- Mitotic phosphorylation of Tau/MAPT modulates cell cycle progression in prostate cancer cellsLetizia Clementi, Samantha Sabetta, Veronica Zelli, Chiara Compagnoni, Alessandra Tessitore, Vincenzo Mattei, Adriano Angelucci · 2023 · Journal of Cancer Research and Clinical Oncology
- Validation of Tau Antibodies for Use in Western Blotting and ImmunohistochemistryMichael J. Ellis, Christiana Lekka, Hanna Tulmin, Darragh Patrick O'Brien, Shalinee Dhayal, Marie‐Louise Zeissler, Jakob Grunnet Knudsen, Benedikt Mathias Kessler, Noel G. Morgan, John A. Todd et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOEYesiltepe, Metin, Yin, Tao, Tambini, Marc, Bao, Hanmei, Pan, Meixia, d’Abramo, Cristina, Giliberto, Luca, Han, Xianlin, D’Adamio, Luciano · 2024 · Cell Communication and Signaling
- Aetiology and pathophysiology of neurodegenerative disordersRakesh Kumar Sahoo, Tanisha Gupta, Smily, Vinay Kumar, Sarita Rani, Umesh Dutta Gupta · 2022 · Elsevier eBooks
- Common and Specific Marks of Different Tau Strains Following Intra-Hippocampal Injection of AD, PiD, and GGT Inoculum in hTau Transgenic MiceIsidró Ferrer, Pol Andrés‐Benito, Margarita Carmona, José Antonio del Rı́o · 2022 · International Journal of Molecular Sciences
- Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimensional Mass Spectrometry-Based Targeted ProteomicsMengying Xu, Meiyan Lu, Wenjun Zhang, Qingwen Jin, Yun Chen · 2021 · Journal of Proteome Research
- Multifactorial etiology of progressive supranuclear palsy (PSP): the genetic componentUlrich Müller, Günter U. Höglinger, Dennis W. Dickson · 2025 · Acta Neuropathologica
- Rats Display Sexual Dimorphism in Phosphorylation of Brain Tau with AgeJiahui Niu, Khalid Iqbal, Fei Liu, Wen Hui Hu · 2021 · Journal of Alzheimer s Disease
- A novel C‐terminal truncated mutation in hCDKL5 protein causing a severe West syndrome: Comparison with previous truncated mutations and genotype/phenotype correlationMarwa Ben Jdila, Chahnez Triki, Bochra Ben Rhouma, Rihab Ben Jomaa, Abir Ben Issa, Leila Keskes, Fatma F. Kamoun, Faiza Fakhfakh · 2018 · International Journal of Developmental Neuroscience
- New Beginnings in Alzheimer’s Disease: The Most Prevalent TauopathyFélix Hernández, Marı́a Llorens-Martı́n, Marta Bolós, Mar Pérez, Raquel Cuadros, Noemí Pallas‐Bazarra, Juan Carlos Zabala, Jesús Ávila · 2018 · Journal of Alzheimer s Disease
- Decoding tau acetylation in Alzheimer’s disease and tauopathies: from site-specific mechanisms to therapeutic horizonsYoonah R. Oh, Min‐Kyoo Shin · 2025 · BMB Reports
- Novel conformation-sensitive antibodies specific to three- and four-repeat tauHitomi Ueno, Ohoshi Murayama, Sumihiro Maeda, Naruhiko Sahara, Jung-Mi Park, Miyuki Murayama, Akihiro Sanda, Kazuhiko Iwahashi, Motoo Matsuda, Akihiko Takashima · 2007 · Biochemical and Biophysical Research Communications
- Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexityYoon A. Kim, Marian Mellén, Çağhan Kızıl, Ismael Santa‐María · 2023 · British Journal of Pharmacology
- A model of traumatic brain injury using human iPSC-derived cortical brain organoidsJesse D. Lai, Joshua E. Berlind, Gabriella Fricklas, Naomi S. Sta Maria, Russell E. Jacobs, Violeta L. Yu, Justin K. Ichida · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Spliceosome protein alterations differentiate hubs of the default mode connectome during the progression of Alzheimer's diseaseSylvia E. Perez, Muhammad Nadeem, Bin He, Jennifer C. Miguel, David G. Moreno, Marta Moreno‐Rodríguez, Michael H. Malek‐Ahmadi, Chadwick M. Hales, Elliott Jay Mufson · 2025 · Brain Pathology
- Quantum dot-based nanodiagnostics for neurodegenerative disorders advances and future perspectivesZeynep Nigar Pınar, Melisa Özkan, Murat Ihlamur · 2025 · Next research.
- Tau protein: Physiological functions and multifaceted roles in neurodegenerative and psychiatric disordersFei Tang, Junfen Wei, Ma-Li Wong, Peng Lei · 2025 · Genomic psychiatry :
- The splice of life: how alternative splicing shapes regulatory and phenotypic evolutionCarissa Emerson Hunter, Yi Xing · 2026 · The EMBO Journal
- Tau and tauopathies across primate species: implications for modeling neurodegenerative disordersJulia C. Colwell, Marina Elena Emborg · 2025 · Frontiers in Aging Neuroscience
- Microtubule‐associated protein tau promotes neuronal class II β‐tubulin microtubule formation and axon elongation in embryonic X enopus laevisYuanyuan Liu, Chen Wang, Giovanny Destin, Ben G. Szaro · 2015 · European Journal of Neuroscience
- Influence of FTDP-17 mutants on circular tau RNAsGiorgi Margvelani, Justin Ralph Welden, Karol Andrea Arizaca Maquera, Jennifer E. Van Eyk, Christopher I. Murray, Sandra C. Miranda Sardón, Stefan Stamm · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- mRNA methods used in dissecting gene expression of the brainTheresa Joseph Kannanayakal, James H. Eberwine · 2005 · Ageing Research Reviews
- Family-based association analysis of theMAPT gene in ParkinsonK. S. Wang, Jerald E. Mullersman, X. F. Liu · 2010 · Journal of Applied Genetics
- What Have We Learned from the Tau Hypothesis?Ricardo Benjamin Maccioni, Gustavo A. Farias, Leonel E. Rojo, M. Alejandra Sekler, Rodrigo Orlando Kuljiš · 2009 · Springer eBooks
- Initial assessment of the spatial learning, reversal, and sequencing task capabilities of knock-in rats with humanizing mutations in the Aβ-coding region of AppPham, Hoa, Yin, Tao, D’Adamio, Luciano · 2022 · PLOS ONE
- Zebrafish Experimental Animal Models for AD: A Comprehensive ReviewRuksar Sande, Angel Pavalu Godad, Gaurav Doshi · 2024 · Current Clinical Pharmacology
- The Biology and Pathobiology of Tau ProteinGarth F. Hall · 2012 · Humana Press eBooks
- Cell Cycle Reactivation, at the Start of Neurodegeneration, Induced by Forskolin and Aniline in Differentiated Neuroblastoma CellsValentina Sturiale, Francesca Bruno, Desiree Brancato, Agata Grazia D’Amico, Grazia Maugeri, Velia D’Agata, Salvatore Saccone, Concetta Federico · 2023 · International Journal of Molecular Sciences
- Recent insights from non-mammalian models of brain injuries: an emerging literatureNicole J. Katchur, Daniel A. Notterman · 2024 · Frontiers in Neurology
- Big Tau: Structure, Evolutionary Divergence, and Emerging Roles in Cytoskeletal Dynamics and TauopathiesItzhak Fischer, Peter W. Baas · 2026 · Cells
- Role of Tau Protein Hyperphosphorylation in Diabetic Retinal NeurodegenerationJingyu Mu, Zengrui Zhang, Chao Jiang, Haoming Geng, Junguo Duan · 2025 · Journal of Ophthalmology
- Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human NeuronsValentina Lacovich, Sonia L. Espíndola, Matías Alloatti, Victorio M. Pozo Devoto, Lucas Eneas Cromberg, Mária E. Čarná, Giancarlo Forte, Jean‐Marc Gallo, Luciana Bruno, Gorazd Bernard Stokin et al. · 2017 · Journal of Neuroscience
- Linkage Analysis of Autopsy-Confirmed Familial Alzheimer Disease Supports an Alzheimer Disease Locus in 8q24Anna Sillén, Jesper Brohede, Charlotte Forsell, Lena Lilius, Jorge Andrade, Jacob Odeberg, Tōru Kimura, Bengt G. Winblad, Caroline Graff · 2011 · Dementia and Geriatric Cognitive Disorders
- Commentary: Genome-wide association study identifies 74 loci associated with educational attainmentFélix Hernández, Jesús Ávila · 2017 · Frontiers in Molecular Neuroscience
- Alternatively spliced MAP4 isoforms have key roles in maintaining microtubule organization and skeletal muscle functionLathan Lucas, Larissa Nitschke, Brandon Nguyen, James Anthony Loehr, George Gerald Rodney, Thomas A. Cooper · 2024 · iScience
- Circular RNAs from the MAPT and TARDBP genes: Novel players in neurodegeneration?Naghme Bagheri, Giorgi Margvelani, Tai-Wei Chiang, Peter T. Nelson, Trees‐Juen Chuang, Stefan Stamm · 2025 · Neurochemistry International
- Post-translational modifications as a regulatory code for tau function in health and diseaseAbigail J. Nordbeck, Bhirisha Sharma, Charles A. Garcia, Jui‐Heng Tseng · 2026 · Frontiers in Dementia
- Tridimensional Structural Analysis of Tau Isoforms Generated by Intronic RetentionIndalo Domene-Serrano, Raquel Cuadros, Félix Hernández, Jesús Ávila, Ismael Santa‐María · 2023 · Journal of Alzheimer s Disease Reports
- G272V and P301L Mutations Induce Isoform Specific Tau Mislocalization to Dendritic Spines and Synaptic Dysfunctions in Cellular Models of 3R and 4R Tau Frontotemporal DementiaKe Yu, Katherine R. Yao, Miguel A. Aguinaga, Jessica M. Choquette, Chengliang Liu, Yuxin Wang, Dezhi Liao · 2024 · Journal of Neuroscience
- Shapeshifter W-Tau Peptide Inhibits Tau Aggregation and Disintegrates Paired Helical FilamentsIndalo Domene-Serrano, Raquel Cuadros, Vega García‐Escudero, Francisco Vallejo-Bedia, Ismael Santa‐María, Laura Vallés‐Saiz, Félix Hernández, Jesús Ávila · 2025 · Biochemistry
- Genetic Correlates of Presenile Dementia and Cognitive Decline in the Armenian Population Following COVID-19: A Case-Control StudyYekaterina Hovhannisyan, Hermine Yeritsyan, Gohar Hakobjanyan, Gayane Petrosyan, Hayk A. Harutyunyan, Armen A. Muradyan, Allen Azizian, Konstantin B. Yenkoyan · 2025 · International Journal of Molecular Sciences
- Tau and Amyloid- Conformational Change to -Sheet Structures as Effectors in the Development of Alzheimer's DiseaseMartha A. De Anda-Hernández, Karla Isabel Lira-de León, Ra�l Mena, Victoria Campos‐Peña, Marco Antonio Meraz‐Ríos · 2012 · InTech eBooks
- Expression and clinical importance of a newly discovered alternative splice variant of the gene for acrosin binding protein found in human brain tumorsBaolong Zheng · 2020 · Asian Biomedicine
- Tau and Axonal TransportEva‐Maria Mandelkow, E. Thies, E. MANDELKOW · 2007 · Springer eBooks
- Tau protein aggregation: A therapeutic target for neurodegenerative diseasesAryan Duggal, Drishti Mahindru, Kirti Baghel, Sanjana Mehrotra, Vijay Kumar Prajapati · 2025 · Advances in protein chemistry and structural biology
- Intron Retention and Alzheimer’s Disease (AD): A Review of Regulation Genes Implicated in ADAyman S. El-Seedy, Véronique Ladevèze · 2025 · Genes
- Structure and function of Full-length TauLaura Vallés‐Saiz, Indalo Domene-Serrano, Ángel J. Picher, Mar Pérez, Vega García‐Escudero, Félix Hernández, Jesús Ávila · 2025 · PLoS ONE
- Genética de la demencia frontotemporalJorge Luis Granadillo de Luque, Ignacio Zarante · 2008 · Redalyc (Universidad Autónoma del Estado de México)
- Emerging pathways in genetic Parkinson’s diseasePatrick Alfryn Lewis · 2008 · FEBS Journal
- Tau haplotypes and ApoE4 do not act in synergy on Alzheimer's diseasePéter Zoltán Álmos, Szatmár Horváth, Ágnes Czibula, István Raskó, Nóra Domján, Anna Juhász, Zoltán Janka, Janos L. Kalman · 2010 · Psychiatry Research
- Nerve Growth Factor Enhances Tau Isoform Expression and Transcription in IMR32 CellsCheryl L. Cragg, Bettina E. Kalisch · 2014 · Neuroscience & Medicine
- The relation between delivery type and tau protein levels in cord bloodTuran Tunç, Abdülbaki Karaoğlu, Tuncer Çaycı, Erkan Demirkaya, Mustafa Kul, Halıl Yaman, Sinan Karadeniz, Tayfun Gungor, Faruk Alpay · 2010 · Pediatrics International
- Protein Misfolding, Neurodegeneration and TauPierfausto Seneci · 2015 · Elsevier eBooks
- Human nuclear tau and agingConcetta Federico, Francesca Bruno, Valentina Sturiale, Agata Grazia D’Amico, Grazia Maugeri, Velia D’Agata, Laura Gil, Salvatore Saccone · 2021 · Elsevier eBooks
- Exploring the Biological Connection Between Tau and PrPC in Neuronal Cells: GSK3β as a Possible Key PlayerRosalina Gavı́n, José Antonio del Rı́o · 2025 · Molecular Neurobiology
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- Ribosome impairment, tau alternative splicing, and stress granules: a convergent axis of neuronal vulnerability driving Alzheimer's diseaseMirco Masi, Chiara Oliviero, Stefano M. Govoni, Benjamin L. Wolozin, Marco Racchi, Erica Buoso · 2026 · European Journal of Pharmacology
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- Tau and Intracellular Transport in NeuronsEva‐Maria Mandelkow, Edda Thies, Sven Konzack, Eva‐Maria Mandelkow · 2009 · Research and perspectives in Alzheimer's disease
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- Tau PathologyNicolas Sergeant, Luc Buée · 2010 · Advances in neurobiology
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- Targets and Small Molecules Against Tauopathies. Part 1: From Genes to Soluble, Aggregation-Prone Tau ProteinsPierfausto Seneci · 2014 · Elsevier eBooks
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- Conformation of Human Microtubule Associated Protein-TauSadasivam Jeganathan� · 2008 · Max Planck Institute for Plasma Physics
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- Implication du complexe récepteur 5-HT4/APP/ADAM10 dans la voie non-amyloïdogénique de la maladie d’AlzheimerMaud Cochet · 2011 · theses.fr (ABES)
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