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Themes and variations in riboswitch structure and function
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Riboswitches are structured RNAs typically found in the 5'-untranslated regions of bacterial mRNAs where they regulate gene expression in response to binding a small molecule or ion.
“Riboswitches are structured RNAs that are typically found in the 5′-untranslated regions of bacterial mRNAs where they regulate the expression of genes in response to binding a small molecule or ion (Breaker, 2011; Peselis and Serganov, 2014; Serganov and Nudler, 2013).”
From Small Molecule Fluoride Toxicity Agonists (2015) · cites this paper as Peselis and Serganov, 2014
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Adenine riboswitches and gene activation by disruption of a transcription terminator
Mandal, M., & Breaker, R. R. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb710 · Cited by 514
Structure and Mechanism of a Metal-Sensing Regulatory RNA
Dann, C. E., Wakeman, C. A., Sieling, C. L., Baker, S. C., Irnov, I., & Winkler, W. C. (2007) · Cell · doi:10.1016/j.cell.2007.06.051 · Cited by 386
Metabolite recognition principles and molecular mechanisms underlying riboswitch function
Serganov, A., & Patel, D. J. (2012) · Annual Review of Biophysics · doi:10.1146/annurev-biophys-101211-113224 · Cited by 160
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Small Molecule Fluoride Toxicity Agonists
Nelson, J. W., Plummer, M. S., Blount, K. F., Ames, T. D., & Breaker, R. R. (2015) · Chemistry & Biology · doi:10.1016/j.chembiol.2015.03.016 · Cited by 30
Metadata
- Authors
- Peselis, A., & Serganov, A.
- Venue
- Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 1839
- Issue
- 10
- Pages
- 908-918
- ISSN
- 1874-9399
- PMC
- PMC4643838
- Cited by
- 102
- References
- 3
- Language
- en
- Funders
- New York University Medical Center
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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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