Physiologic functions of PP2A: Lessons from genetically modified mice

Reynhout, Sara, Janssens, Veerle·2019·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
DOI 10.1016/j.bbamcr.2018.07.010

Cited by (126)

Items 101–126 of 126

  1. Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation
    Sébastien Coassolo, Nairie Michaelian, Timurs Maculins, Caleigh M. Azumaya, Tommy K. Cheung, Jianping Yin, Inna Zilberleyb, Kanika Bajaj Pahuja, Thomas P. Garner, Ted Lau et al. · 2026 · Nature
  2. The PP2A/4/6 subfamily of phosphoprotein phosphatases regulates DAF-16 and confers resistance to environmental stress in postreproductive adult C. elegans
    Rebecca S. Rivard, Julia M. Morris, Matthew J. Youngman · 2020 · PLoS ONE
  3. Loss of protein phosphatase 2A regulatory subunit PPP2R5A is associated with increased incidence of stress-induced proarrhythmia
    Florentina Pluteanu, Dennis Glaser, Fabian Massing, Jan Sebastian Schulte, Uwe Kirchhefer · 2024 · Frontiers in Cardiovascular Medicine
  4. Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α
    Nicola M. Sergienko, Adam J. Trewin, Helen Kiriazis, Antonia J. A. Raaijmakers, Daniel G. Donner, Victoria C. Garside, Kelly Smith, James R. Bell, Kimberley M. Mellor, Lea M.D. Delbridge et al. · 2024 · npj Metabolic Health and Disease
  5. Tissue-Specific Expression of the Porcine DHRS3 Gene and Its Impact on the Proliferation and Differentiation of Myogenic Cells
    Jifeng Li, Yong Ruan, Chuanmei Jiang, Jinkui Sun, Dongwei An, Bo Zhou, Huan Liu, Ziyang Li, Houqiang Xu · 2025 · Animals
  6. LB100 attenuates methamphetamine-induced behavioral sensitization by inhibiting the Raf1-ERK 1/2 cascade in the caudate putamen
    Qing Shang, Min Liang, Jing Xiao, Baoyao Gao, Hongyan Qian, Jing Wang, Gang Chen, Jie Fang, Tao Li, Xinshe Liu · 2021 · Neuroreport
  7. Network‐based analysis predicts interacting genetic modifiers from a meta‐mapping study of spike–wave discharge in mice
    Montana Kay Lara, Jeffrey L. Brabec, Amanda E. Hernan, Rod C. Scott, Anna L. Tyler, J. Matthew Mahoney · 2024 · Genes Brain & Behavior
  8. Catecholaminergic stress results in signs of heart failure in PP2A-PR72 overexpressor mice
    Paul Pauls, Larissa Fabritz, Julius R. Herting, Amanda Johann, Jule H. König, Jan Sebastian Schulte, Matthias Dodo Seidl, Carolina E. Soppa, Uwe Kirchhefer · 2025 · Journal of Molecular and Cellular Cardiology
  9. Protein phosphatase 2A regulates senescence and immunogenicity in medulloblastoma models
    Winson S. Ho, Isha Mondal, Jingjing Liu, Raymond Sun, Jiawei Huo, Chao Gao, Oishika Das, Daren Tieu, Jingqi Sun, Hanchen Lin et al. · 2026 · Journal of Clinical Investigation
  10. PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosis
    Zhengwei Zhang, Beier Tong, Jie Liu, Jieyuan Feng, Linyang Song, Huawei Wang, Mengting Ke, Chengkai Xu, Yancheng Xu · 2023 · Experimental and Therapeutic Medicine
  11. PRG4/CD44/PP2A Signaling Axis: A Significant Regulator of Gout Arthritis
    Sandy Elsayed · 2023 · Chapman University Digital Commons (Chapman University)
  12. Data from Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy
    Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M. Fernandes Neto, Frank P. A. van Gemert, Soufiane M. C. Mourragui, Chrysa Papagianni, Hendrik J. Kuiken, Sara Mainardi, Daniel Alvarez Villanueva et al. · 2024
  13. Amyloid-Like Assembly During Embryogenesis Activates Herzog, a Novel Prion-Like Phosphatase
    Zelha Nil, Rubén Hervás Millán, Therese M. Gerbich, Paulo Leal, Zulin Yu, Anita Saraf, Mihaela E. Sardiu, Jeffrey J. Lange, Kexi Yi, Jay R. Unruh et al. · 2019 · SSRN Electronic Journal
  14. Faculty Opinions recommendation of PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation.
    Cheng‐Ming Chiang · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  15. PP2A phosphatase regulates cell-type specific cytoskeletal organization to drive dendritic diversification
    Shatabdi Bhattacharjee, Erin N. Lottes, Sumit Nanda, Andre Golshir, Atit A. Patel, Giorgio A. Ascoli, Daniel N. Cox · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  16. The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cells
    Alexandra Nguyen, Alessa K. Leydecker, Al‐Hassan M. Mustafa, Janine Murr, Falk Butter, Oliver Holger Krämer · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  17. Additional file 1 of The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells
    Alexandra Nguyen, Mustafa, Al-Hassan M., Alessa K. Leydecker, Melisa Halilovic, Janine Murr, Butter, Falk, Oliver Holger Krämer · 2024 · Figshare
  18. Additional file 1 of GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch
    Guy Nadel, Yao, Zhong, Ehud Wainstein, Cohen, Izel, Ben-Ami, Ido, Amir Schajnovitz, Galia Maik-Rachline, Zvi Naor, Benjamin A. Horwitz, Rony Seger · 2022 · Figshare
  19. Additional file 1 of Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis
    Guy Nadel, Yao, Zhong, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Ziv, Tamar, Zvi Naor, Arie Admon, Rony Seger · 2024 · Figshare
  20. PP2A dysfunction mediated by PPP2R1A deficiency drives cGAS–STING-dependent hyperinflammation in SLE CD14+ monocytes
    Xuan Fang, Xi Wen, Hong Zhang, Zhu Chen · 2026 · Clinical Rheumatology
  21. The AAA-ATPase Yta4 inhibits the interaction between Ppa2 and Atg43 to promote Atg43 phosphorylation and mitophagy
    Ke Liu, Jiajia He, Yifan Wu, Chenhui Zhao, Shuaijie Yan, Fangyuan Xiong, Xing Liu, Xuebiao Yao, Chuanhai Fu · 2026 · Journal of Biological Chemistry
  22. Regulation of gametophyte-to-sporophyte transitions during the file cycle of Ectocarpus
    Haiqin Yao · 2019 · theses.fr (ABES)
  23. Dual inhibition of PP2A and WEE1 induces apoptosis and mitotic catastrophe in cancer cells
    Al‐Hassan M. Mustafa, Alexandra Nguyen, Sophie Kreissig, Yanira Zeyn, Yesim Melisa Gürbüzoglu, Stefan Stoldt, Matthias Bros, Markus Philipp Radsak, Walburgis Brenner, Linping Chen-Wichmann et al. · 2026 · Biomedicine & Pharmacotherapy
  24. Protein phosphatase 2A impairs cardiac uptake of glucose in the mammalian heart
    Katarína Hadová, Daniel Gündel, Torsten Knieß, Peter Brust, Ján Klimas, Joachim Neumann, Ulrich Gergs · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
  25. Microcystin-LR exposure induces cartilage degeneration and dysregulates osteoarthritis-associated targets: an integrative computational and experimental study
    Zhifang Tang, Zuyong feng, Zhiyu Liang, Shijie Liao, XiaoFei Ding · 2026 · Frontiers in Pharmacology
  26. BindingDB Entry 50017445: The Pursuit of Enzyme Activation: A Snapshot of the Gold Rush.
    BindingDB · 2023 · UC San Diego