Role of mTOR in physiology and pathology of the nervous system

Swiech, Lukasz, Perycz, Malgorzata, Malik, Anna, Jaworski, Jacek·2008·Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
DOI 10.1016/j.bbapap.2007.08.015

Cited by (338)

Items 101–200 of 338

  1. TGF‑β1 promotes the osteoinduction of human osteoblasts via the PI3K/AKT/mTOR/S6K1 signalling pathway
    Zhaodong Zhang, Xiuzhi Zhang, Dewei Zhao, Baoyi Liu, Benjie Wang, Weiting Yu, Junlei Li, Xiaobing Yu, Fang Cao, Guoshuang Zheng et al. · 2019 · Molecular Medicine Reports
  2. Emerging Treatments in the Management of Tuberous Sclerosis Complex
    Michael H. Kohrman · 2012 · Pediatric Neurology
  3. Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries
    Aruni S. Arachchige Don, Chi Kwan Tsang, Tatiana M. Kazdoba, Gabriella D’Arcangelo, Wise Young, Xi Zheng · 2012 · Drug Discovery Today
  4. Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats
    Vez Repunte‐Canonigo, Céline Lefèbvre, Olivier George, Tomoya Kawamura, Marisela Morales, George F. Koob, Andrea Califano, Eliezer Masliah, Pietro Paolo Sanna · 2014 · Molecular Neurodegeneration
  5. Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway
    Eunchai Kang, Danye Jiang, Yun Kyoung Ryu, Sanghee Lim, Minhye Kwak, Christy Gray, Michael Xu, Jun H. Choi, Sue Junn, Ji‐Eun Kim et al. · 2017 · PLoS Biology
  6. The Angiogenic Factor Angiopoietin-1 Is a Proneurogenic Peptide on Subventricular Zone Stem/Progenitor Cells
    Alexandra I. Rosa, Joana Gonçalves, Luísa Cortes, Liliana Inácio Bernardino, João Oliveira Malva, Fabienne Agasse · 2010 · Journal of Neuroscience
  7. mTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injury
    Lingli Liang, Tao Bo, Longchang Fan, Myron Yaster, Yi Zhang, Yuan‐Xiang Tao · 2013 · Brain Research
  8. Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy
    Paul S. Buckmaster, Xiling Wen · 2011 · Epilepsia
  9. Mossy fiber sprouting in the dentate gyrus
    Paul S. Buckmaster · 2010 · Epilepsia
  10. Neuritin Activates Insulin Receptor Pathway to Up-regulate Kv4.2-mediated Transient Outward K+ Current in Rat Cerebellar Granule Neurons
    Jin-Jing Yao, Xiao-Fei Gao, Chi-Wing Chow, Xiao-Qin Zhan, Changlong Hu, Yan‐Ai Mei · 2012 · Journal of Biological Chemistry
  11. Molecular Therapies for Tuberous Sclerosis and Neurofibromatosis
    Franz, David Neal, Weiss, Brian D. · 2012 · Current Neurology and Neuroscience Reports
  12. Prolonged abstinence from developmental cocaine exposure dysregulates BDNF and its signaling network in the medial prefrontal cortex of adult rats.
    G. Giannotti, L. Caffino, F. Calabrese, G. Racagni, M. Riva, F. Fumagalli · 2014 · International Journal of Neuropsychopharmacology
  13. mTORC2 (Rictor) in Alzheimer’s Disease and Reversal of Amyloid-β Expression-Induced Insulin Resistance and Toxicity in Rat Primary Cortical Neurons
    Lee, Han-Kyu, Kwon, Bumsup, Lemere, Cynthia A., de la Monte, Suzanne, Itamura, Kyohei, Ha, Austin Y., Querfurth, Henry W. · 2017 · Journal of Alzheimer's Disease
  14. Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury
    Minjee Kwon, Jeongsoo Han, Un Jeng Kim, Myeounghoon Cha, Sun Woo Um, Sun Joon Bai, Seong‐Karp Hong, Bae Hwan Lee · 2017 · Frontiers in Molecular Neuroscience
  15. Sleep, Plasticity and the Pathophysiology of Neurodevelopmental Disorders: The Potential Roles of Protein Synthesis and Other Cellular Processes
    Dante Picchioni, R. Michelle Reith, Jeffrey Nadel, Carolyn Beebe Smith · 2014 · Brain Sciences
  16. Pediatric low-grade gliomas and the need for new options for therapy: why and how?
    Ibrahim A. Qaddoumi, Iyad Yasin Sultan, Alberto Broniscer · 2009 · Cancer Biology & Therapy
  17. Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities
    Pooja Teotia, Matthew J. Van Hook, Christopher Wichman, R. Rand Allingham, Michael A. Hauser, Iqbal Ahmad · 2017 · Stem Cells
  18. The role of Akt (protein kinase B) and protein kinase C in ischemia–reperfusion injury
    Ethan Y. Zhao, Aslan Efendizade, Lipeng Cai, Yuchuan Ding · 2016 · Neurological Research
  19. Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions
    Jordan B. Jahrling, Rémi-Martin Laberge · 2015 · Current Topics in Medicinal Chemistry
  20. Cadmium Activates Reactive Oxygen Species-dependent AKT/mTOR and Mitochondrial Apoptotic Pathways in Neuronal Cells.
    Yan Yuan, Yi Wang, Fei Fei Hu, Chen Yang Jiang, Ya Jing Zhang, Jin Yang, Shi Wen Zhao, Jian Hong Gu, Xue Zhong Liu, Jian Chun Bian et al. · 2016 · PubMed
  21. Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)
    Anna R. Malik, Małgorzata Urbańska, Matylda Macias, Agnieszka Skalecka, Jacek Jaworski · 2012 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  22. Rheb Activation in Subventricular Zone Progenitors Leads to Heterotopia, Ectopic Neuronal Differentiation, and Rapamycin-Sensitive Olfactory Micronodules and Dendrite Hypertrophy of Newborn Neurons
    Carlos Lafourcade, Tiffany V. Lin, David M. Feliciano, Longbo Zhang, Lawrence S. Hsieh, Angélique Bordey · 2013 · Journal of Neuroscience
  23. ZT-25, a new vacuolar H+-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells
    Yapeng Lu, Rui Zhang, Siyuan Liu, Yu Chen Zhao, Jing Gao, Li Zhu · 2015 · European Journal of Pharmacology
  24. Mossy Fiber Sprouting in the Dentate Gyrus
    Paul S. Buckmaster · 2012 · Oxford University Press eBooks
  25. Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment
    Matylda Macias, Magdalena Błażejczyk, Paulina Kaźmierska, Bartosz Caban, Agnieszka Skalecka, Bartosz Tarkowski, Anna Rodo, Jan Konopacki, Jacek Jaworski · 2013 · PLoS ONE
  26. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1)
    Ivelisse Sánchez, Eudald Balagué, Antoni Matilla‐Dueñas · 2016 · Human Molecular Genetics
  27. Human retinal ganglion cell axon regeneration by recapitulating developmental mechanisms: effects of recruitment of the mTOR pathway
    Pooja Teotia, Matthew J. Van Hook, Dietmar Fischer, Iqbal Ahmad · 2019 · Development
  28. Celastrol prevents cadmium‐induced neuronal cell death via targeting JNK and PTEN‐Akt/ mTOR network
    Sujuan Chen, Chenjian Gu, Chong Xu, Jinfei Zhang, Yijiao Xu, Qian Ren, Min Guo, Shile Huang, Long Chen · 2013 · Journal of Neurochemistry
  29. Investigational NMDA receptor modulators for depression
    Bernadeta Szewczyk, Agnieszka Pałucha-Poniewiera, Ewa Poleszak, Andrzej Pilc, Gabriel Nowak · 2011 · Expert Opinion on Investigational Drugs
  30. Mechanisms Underlying the Effect of Acupuncture on Cognitive Improvement: A Systematic Review of Animal Studies
    Mason Chin Pang Leung, Ka Keung Yip, Janice Yuen Shan Ho, Flora K.W. Siu, Wai Chin Li, Belinda Garner · 2014 · Journal of Neuroimmune Pharmacology
  31. Celastrol prevents cadmium‐induced neuronal cell death by blocking reactive oxygen species‐mediated mammalian target of rapamycin pathway
    Ruijie Zhang, Nana Zhang, Hai Zhang, Chunxiao Liu, Xiaoqing Dong, Xiaoxue Wang, Yu Zhu, Chong Xu, Lei Liu, Sijun Yang et al. · 2016 · British Journal of Pharmacology
  32. Mechanisms of acupuncture on vascular dementia—A review of animal studies
    Ye Yang, Wen Xian Zhu, Xuerui Wang, Jing‐Wen Yang, Ling‐Yong Xiao, Yi Liu, Xin Zhang, Cun‐Zhi Liu · 2016 · Neurochemistry International
  33. Rapamycin suppresses PTZ-induced seizures at different developmental stages of zebrafish
    Anna Maria Siebel, Fabiano Peres Menezes, Isabel da Costa Schaefer, Bárbara Dutra Petersen, Carla Denise Bonan · 2015 · Pharmacology Biochemistry and Behavior
  34. Striatal Akt/GSK3 signaling pathway in the development of L-Dopa-induced dyskinesias in MPTP monkeys
    Morissette, Marc, Samadi, Pershia, Tahar, Abdallah Hadj, Bélanger, Nancy, Di Paolo, Thérèse · 2010 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  35. mTOR inhibitors as a new therapeutic option for epilepsy
    Paolo Curatolo, Romina Moavero · 2013 · Expert Review of Neurotherapeutics
  36. Role of the AMPA receptor in antidepressant effects of ketamine and potential of AMPA receptor potentiators as a novel antidepressant
    Suzuki, Atsushi, Hara, Hiroe, Kimura, Haruhide · 2023 · Neuropharmacology
  37. Autophagy in Alzheimer’s disease
    Moreira, Paula I, Santos, Renato X, Zhu, Xiongwei, Lee, Hyoung-gon, Smith, Mark A, Casadesus, Gemma, Perry, George · 2010 · Expert Review of Neurotherapeutics
  38. FLZ protects dopaminergic neuron through activating protein kinase B/mammalian target of rapamycin pathway and inhibiting RTP801 expression in Parkinson's disease models
    X.-Q. Bao, Xiangchen Kong, C. Qian, D. Zhang · 2011 · Neuroscience
  39. ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats
    Lidan Hu, Z.G. Sun, Yimin Wen, Guozhi Cheng, Shimo Wang, H.B. Zhao, X.R. Zhang · 2010 · Neuroscience
  40. Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans
    Melana E. Yanos, Christopher F. Bennett, Matt R. Kaeberlein · 2012 · Current Genomics
  41. Mechanistic/mammalian target of rapamycin: Recent pathological aspects and inhibitors
    Mohammed S. Abdel‐Maksoud, Mohammed I. El–Gamal, Dalia Reyane Benhalilou, Sandy Ashraf, Shatha Abdulghaffar Mohammed, Chang‐Hyun Oh · 2018 · Medicinal Research Reviews
  42. Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival
    Tinatin Zurashvili, Lluís Cordón-Barris, Gerard Ruiz‐Babot, Xiangyu Zhou, José Miguel Lizcano, Néstor Gómez, Lydia Giménez‐Llort, José Ramón Bayascas · 2012 · Molecular and Cellular Biology
  43. The mTOR Signaling Pathway Regulates Pain-Related Synaptic Plasticity in Rat Entorhinal-Hippocampal Pathways
    Dan Lyu, Wenli Yu, Ning Tang, Ruirui Wang, Zhenyu Zhao, Fang Xie, Yongjin He, Hongyin Du, Jun Chen · 2013 · Molecular Pain
  44. Mechanism of Cone Degeneration in Retinitis Pigmentosa
    De-Juan Song, Xiao-Li Bao, Bin Fan, Guangyu Li · 2022 · Cellular and Molecular Neurobiology
  45. Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin
    Kiyoshi Okada, Hiroyuki Tanaka, Ko Temporin, Michio T. OKAMOTO, Yusuke Kuroda, Hisao Moritomo, Tsuyoshi Murase, Hideki Yoshikawa · 2011 · Neuroscience Letters
  46. CUL4B-deficiency in humans: Understanding the clinical consequences of impaired Cullin 4-RING E3 ubiquitin ligase function
    Claudia Kerzendorfer, Lesley Hart, Rita Colnaghi, Gillian Carpenter, Diana Alcantara, Emily A. Outwin, Antony M. Carr, Mark O’Driscoll · 2011 · Mechanisms of Ageing and Development
  47. A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans
    Marina Kniazeva, Huanhu Zhu, Aileen K. Sewell, Min Han · 2015 · Developmental Cell
  48. mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons
    Agnieszka Skalecka, Ewa Liszewska, Robert Bilinski, Christos G. Gkogkas, Arkady Khoutorsky, Anna R. Malik, Nahum Sonenberg, Jacek Jaworski · 2016 · Developmental Neurobiology
  49. Celastrol Attenuates Cadmium‐Induced Neuronal Apoptosis via Inhibiting Ca2+‐CaMKII‐Dependent Akt/mTOR Pathway
    Ruijie Zhang, Yu Zhu, Xiaoqing Dong, Beibei Liu, Nana Zhang, Xiaoxue Wang, Lei Liu, Chong Xu, Shile Huang, Long Chen · 2016 · Journal of Cellular Physiology
  50. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes
    Veronica Granatiero, Nicole M. Sayles, Angela Maria Savino, Csaba Konràd, Michael G. Kharas, Hibiki Kawamata, Giovanni Manfredi · 2021 · Autophagy
  51. mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice
    Shan Wang, Shanlei Zhou, Fang-yuan Min, Jin-ju Ma, Xiajie Shi, Erika Bereczki, Jing Wu · 2014 · Metabolic Brain Disease
  52. Rapamycin blocks the antidepressant effect of ketamine in task-dependent manner
    Kristína Holubová, Lenka Kletečková, Martina Škurlová, Jan Říčný, Aleš Stuchlík, Karel Valeš · 2016 · Psychopharmacology
  53. The DPYSL2 gene connects mTOR and schizophrenia
    X Pham, G Song, Shuxuan Lao, Loyal A. Goff, H Zhu, David L. Valle, Dimitrios Avramopoulos · 2016 · Translational Psychiatry
  54. Eaten alive: autophagy and neuronal cell death after hypoxia-ischemia.
    Charleen T. Chu · 2008 · American Journal of Pathology
  55. Analysis of proteins that rapidly change upon mechanistic/mammalian target of rapamycin complex 1 (mTORC1) repression identifies parkinson protein 7 (PARK7) as a novel protein aberrantly expressed in tuberous sclerosis complex (TSC)
    Niere, Farr, Namjoshi, Sanjeev, Song, Ehwang, Dilly, Geoffrey A., Schoenhard, Grant, Zemelman, Boris V., Mechref, Yehia, Raab-Graham, Kimberly F. · 2016 · Molecular & Cellular Proteomics
  56. The Naked Mole-Rat
    Kaitlyn N. Lewis, Rochelle Buffenstein · 2015 · Elsevier eBooks
  57. Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B
    Vincent Ries, Hsiao‐Chun Cheng, Amy Baohan, Tatyana Kareva, Tinmarla Frances Oo, Margarita Rzhetskaya, Ross J. Bland, Matthew J. During, Nikolai G. Kholodilov, Robert E. Burke · 2009 · Journal of Neurochemistry
  58. mTOR Signaling and Entrainment of the Mammalian Circadian Clock.
    Ruifeng Cao, Karl H. Obrietan · 2010 · PubMed
  59. Signaling Pathways Involved in Antidepressant-Induced Cell Proliferation and Synaptic Plasticity
    Fuencisla Pilar-Cuéllar, Rebeca Vidal, Álvaro Díaz, Elena Castro, Severiano Dos-Anjos, Verónica Inés Vargas, Beatriz Romero, Elsa M. Valdizán · 2014 · Current Pharmaceutical Design
  60. Sinomenine attenuates chronic inflammatory pain in mice
    Shuo Li, Jing Han, Dongsheng Wang, Qi Yang, Bin Feng, Wenbo Kang, Le Yang, Gang Liu, Ming Zhao · 2016 · Metabolic Brain Disease
  61. Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2
    Alicja Koscielny, Anna R. Malik, Ewa Liszewska, Justyna Zmorzyńska, Aleksandra Tempes, Bartosz Tarkowski, Jacek Jaworski · 2017 · Molecular Neurobiology
  62. Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase–mTORC1 Translational Pathway
    Charlotte C. Bavley, Richard C. Rice, Delaney K. Fischer, Amanda K. Fakira, Maureen Byrne, Maria Kosovsky, Bryant K. Rizzo, Dolores Del Prete, Armin Alaedini, José A. Morón et al. · 2018 · Journal of Neuroscience
  63. Genome-Wide Analysis of miRNA Signature in the APPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease
    Hongxue Luo, Qi Wu, Xiaoyang Ye, Yi Xiong, Jinyong Zhu, Junyu Xu, Yarui Diao, Duo Zhang, Maosheng Wang, Qiu JinHua et al. · 2014 · PLoS ONE
  64. Protective conditioning of the brain: expressway or roadblock?
    Philipp Mergenthaler, Ulrich Dirnagl · 2011 · The Journal of Physiology
  65. Elevation of hepatic autophagy and antioxidative capacity by endurance exercise is associated with suppression of apoptosis in mice
    Insu Kwon, Wankeun Song, Yongchul Jang, Myung Dong Choi, Debra M. Vinci, Youngil Lee · 2019 · Annals of Hepatology
  66. Epidermal growth factor receptor antagonists and CNS axon regeneration: Mechanisms and controversies
    Martin Berry, Zubair Ahmed, Michael R. Douglas, Ann Logan · 2010 · Brain Research Bulletin
  67. mTOR signaling in the nucleus accumbens mediates behavioral sensitization to methamphetamine
    Shin‐Han Huang, Wan-Rong Wu, Liming Lee, Peirong Huang, Jin‐Chung Chen · 2018 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  68. Inhibition of MicroRNA-96 Ameliorates Cognitive Impairment and Inactivation Autophagy Following Chronic Cerebral Hypoperfusion in the Rat
    Peifang Liu, Peijia Liu, Zhiyong Wang, Shaohong Fang, Yuting Liu, Jinhua Wang, Wenjuan Liu, Ning Wang, Lixia Chen, Jianjian Wang et al. · 2018 · Cellular Physiology and Biochemistry
  69. MicroRNAs: Game Changers in the Regulation ofα-Synuclein in Parkinson’s Disease
    Liang Zhao, Zhiqin Wang · 2019 · Parkinson s Disease
  70. Chronic activation of the D2 dopamine autoreceptor inhibits synaptogenesis in mesencephalic dopaminergic neurons in vitro
    Caroline Fasano, A. Poirier, Luc DesGroseillers, Louis‐Éric Trudeau · 2008 · European Journal of Neuroscience
  71. Thyroid hormone-dependent development of early cortical networks: temporal specificity and the contribution of trkB and mTOR pathways
    Sören Westerholz, Ana D. de Lima, Thomas Voigt · 2013 · Frontiers in Cellular Neuroscience
  72. Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis
    Chunxiao Liu, Yangjing Ye, Qian Zhou, Ruijie Zhang, Hai Zhang, Wen Liu, Chong Xu, Lei Liu, Shile Huang, Long Chen · 2016 · Oncotarget
  73. Pharmacogenetic predictor of extrapyramidal symptoms induced by antipsychotics: Multilocus interaction in the mTOR pathway
    Sergi Mas, Patricia Gassó, Marie A Ritter, Cristina Malagelada, Miquel Bernardo, Amàlia Lafuente · 2014 · European Neuropsychopharmacology
  74. Functional protection of learning and memory abilities in rats with vascular dementia
    Hui-Yun Yang, O. Shi, Yan-Jiao Jin, P. Henrich-Noack, Haixuan Qiao, Chun-Quan Cai, H. Tao, Xin Tian · 2014 · Restorative Neurology and Neuroscience
  75. Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs
    Emanuela Santini, Eric Klann · 2011 · Frontiers in Behavioral Neuroscience
  76. Extensive Use of RNA-Binding Proteins inDrosophilaSensory Neuron Dendrite Morphogenesis
    Eugenia C. Olesnicky, Darrell J. Killian, Evelyn Garcia, Mary C. Morton, Alan R Rathjen, Ismail Sola, Elizabeth R. Gavis · 2013 · G3 Genes Genomes Genetics
  77. Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity
    Daniela Cota · 2009 · Physiology & Behavior
  78. Nobiletin prevents cadmium-induced neuronal apoptosis by inhibiting reactive oxygen species and modulating JNK/ERK1/2 and Akt/mTOR networks in rats
    Youyang Qu, Yu Liu, Li Chen, Yanmei Zhu, Xingjun Xiao, Di Wang, Yulan Zhu · 2018 · Neurological Research
  79. Early 5‐HT6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse
    Coralie Berthoux, Al Mahdy Hamieh, Angelina Rogliardo, Emilie L Doucet, Camille Coudert, Fabrice Ango, Katarzyna Grychowska, Séverine Chaumont‐Dubel, Paweł Zajdel, Rafael J. Maldonado et al. · 2020 · EMBO Molecular Medicine
  80. mTOR as a Potential Target for the Treatment of Microbial Infections, Inflammatory Bowel Diseases, and Colorectal Cancer
    Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Bismillah Mubeen, Sami Ibrahim Alzarea, Waleed Hassan Almalki, Salwa D. Al-Qahtani, Eman M. Atiya, Fahad Ahmed Al-Abbasi, Fatima Ali, Inam Ullah et al. · 2022 · International Journal of Molecular Sciences
  81. Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice.
    Alev Deli, Katharina Schipany, M. Rosner, H. Höger, A. Pollak, Lin Li, M. Hengstschläger, G. Lubec · 2012 · Behavioural Brain Research
  82. mTOR signaling contributes to motor skill learning in mice
    Yan Bergeron, Laure Chagniel, Genevià ̈ve Bureau, Guy Massicotte, Michel Cyr · 2014 · Frontiers in Molecular Neuroscience
  83. Signaling Pathway in Early Brain Injury after Subarachnoid Hemorrhage: News Update
    Chengyuan Ji, Gang Chen · 2016 · Acta neurochirurgica. Supplementum
  84. Blockade of excitatory synaptogenesis with proximal dendrites of dentate granule cells following rapamycin treatment in a mouse model of temporal lobe epilepsy
    Ruth M. Yamawaki, Khushdev K. Thind, Paul S. Buckmaster · 2014 · The Journal of Comparative Neurology
  85. mTOR signalling: jack-of-all-trades
    Yassine El Hiani, Emmanuel Eroume A Egom, Xian‐Ping Dong · 2018 · Biochemistry and Cell Biology
  86. The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis
    Makoto Endo, Joseph E. Druso, Richard A. Cerione · 2020 · Journal of Biological Chemistry
  87. HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway
    Ting Zhu, Deming Zhao, Zhiqi Song, Zhen Yuan, Chaosi Li, Yunsheng Wang, Xiangmei Zhou, Xiaomin Yin, Muhammad Farooque Hassan, Lifeng Yang · 2015 · Neurobiology of Aging
  88. The PI3K/Akt/mTOR signaling pathway plays a role in regulating aconitine-induced autophagy in mouse liver
    Hanqi Yang, Hui Wang, Yanbing Liu, Lin Yang, Lu Sun, Yanan Tian, Baoyu Zhao, Hao Xin Lu · 2019 · Research in Veterinary Science
  89. In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome
    Tiantian Wang, Laura G C de Kok, Rob Willemsen, Ype Elgersma, J. Gerard G. Borst · 2015 · Frontiers in Cellular Neuroscience
  90. Asiaticoside: Attenuation of rotenone induced oxidative burden in a rat model of hemiparkinsonism by maintaining the phosphoinositide-mediated synaptic integrity
    Margabandhu Gopi, Vanisree Arambakkam Janardhanam · 2017 · Pharmacology Biochemistry and Behavior
  91. mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways
    Farr Niere, Kimberly F. Raab‐Graham · 2017 · Frontiers in Cellular Neuroscience
  92. Rheb-mTOR activation rescues Aβ-induced cognitive impairment and memory function by restoring miR-146 activity in glial cells
    Dipayan De, Ishita Mukherjee, Subhalakshmi Guha, Ramesh Kumar Paidi, Saikat Chakrabarti, Subhas Chandra Biswas, Suvendra N. Bhattacharyya · 2021 · Molecular Therapy — Nucleic Acids
  93. Molecular mechanisms of sex hormones in the development and progression of Alzheimer's disease
    Saeed Radaghdam, Vahidreza Karamad, Alireza Nourazarian, Behrouz Shademan, Fatemeh Khaki‐Khatibi, Masoud Nikanfar · 2021 · Neuroscience Letters
  94. Phenolic Acid Intake, Delivered Via Moderate Champagne Wine Consumption, Improves Spatial Working Memory Via the Modulation of Hippocampal and Cortical Protein Expression/Activation
    Giulia Corona, David Vauzour, Justine Hercelin, Claire Michelle Williams, Jeremy P.E. Spencer · 2013 · Antioxidants and Redox Signaling
  95. RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis
    Gao Sun, Richard Reynolds, Isabelle Leclerc, Guy A. Rutter · 2010 · Disease Models & Mechanisms
  96. Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways
    Chong Xu, Chunxiao Liu, Lei Liu, Ruijie Zhang, Hai Zhang, Sujuan Chen, Yan Luo, Long Chen, Shile Huang · 2015 · Neuropharmacology
  97. Molecular interplay between hyperactive mammalian target of rapamycin signaling and Alzheimer’s disease neuropathology in the NS-Pten knockout mouse model
    Samantha L. Hodges, Conner D. Reynolds, Gregory D. Smith, Taylor S. Jefferson, Suzanne O. Nolan, Joaquín N. Lugo · 2018 · Neuroreport
  98. GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells
    Changying Wang, Anqi Huang, Menghua Zhou, Yan‐Ai Mei · 2014 · Biochemical Journal
  99. Diet and Energy-Sensing Inputs Affect TorC1-Mediated Axon Misrouting but Not TorC2-Directed Synapse Growth in a Drosophila Model of Tuberous Sclerosis
    Brian D. Dimitroff, Katie A. Howe, Adrienne L. Watson, Bridget Kelly Campion, Hyun-Gwan Lee, Na Zhao, Michael B. O’Connor, Thomas P. Neufeld, Scott B. Selleck · 2012 · PLoS ONE
  100. The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer’s Disease or Vascular Diseases through Regulating Neuroplasticity
    Shaozhen Ji, Jiayu Duan, Xiaobing Hou, Li Zhou, Weilan Qin, Huanmin Niu, Shuyun Luo, Yunling Zhang, Piu Chan, Xianglan Jin · 2021 · Neural Plasticity