Lipopolysaccharide alters the blood–brain barrier transport of amyloid β protein: A mechanism for inflammation in the progression of Alzheimer’s disease
Jaeger, Laura B., Dohgu, Shinya, Sultana, Rukhsana, Lynch, Jessica L., Owen, Joshua B., Erickson, Michelle A., Shah, Gul N., Price, Tulin O., Fleegal-Demotta, Melissa A., Butterfiled, D. Allan, Banks, William A.·2009·Brain, Behavior, and Immunity
Cited by (281)
Items 201–281 of 281
- Do Periodontal Pathogens or Associated Virulence Factors Have a Deleterious Effect on the Blood-Brain Barrier, Contributing to Alzheimer’s Disease?Mhd Ammar Kouki, Anna Barlach Pritchard, Jane Elizabeth Alder, StJohn Crean · 2021 · Journal of Alzheimer s Disease
- Reciprocal Interactions Between Periodontal Disease and Alzheimer’s Disease: Implications for Mutual Triggering, Exacerbation, and Treatment Interventions—A Comprehensive Review of the LiteratureShatha Gharaibeh, Alameen Alsabbah, Ahmad Alloubani, Abeer Gharaibeh · 2025 · Neurology International
- Cardiovascular Risk Factors, Alzheimer’s Disease, and the MIND Diet: A Narrative Review from Molecular Mechanisms to Clinical OutcomesAmirhossein Ataei Kachouei, Saiful Singar, Amber Wood, Jason D. Flatt, Sara K. Rosenkranz, Richard R. Rosenkranz, Neda Sara Akhavan · 2025 · Nutrients
- Inflammation Spreading: Negative Spiral Linking Systemic Inflammatory Disorders and Alzheimer’s DiseaseJunjun Ni, Zhou Wu · 2021 · Frontiers in Cellular Neuroscience
- Avanafil mediated dual inhibition of IKKβ and TNFR1 in an experimental paradigm of Alzheimer’s disease: in silico and in vivo approachPrasada Chowdari Gurram, Sairaj Satarker, Gautam Kumar, Farmiza Begum, Chetan Hasmukh Mehta, Usha Y. Nayak, Jayesh Mudgal, Devinder S Arora, Madhavan Nampoothiri · 2022 · Journal of Biomolecular Structure and Dynamics
- Efflux transport of serum amyloid P component at the blood-brain barrierSzilvia Veszelka, Judit Laszy, Tamás Pázmány, László Németh, Izabella Obál, L. Fábián, Gábor Szabó, Csongor S. Ábrahám, Mária A. Deli, Zoltán Urbányi · 2013 · European Journal of Microbiology and Immunology
- The role of intestinal endotoxemia in a rat model of aluminum neurotoxicityFeng Wang, Rui-Xia Guo, Wenxing Li, Baofeng Yu, Bai Han, Lixin Liu, Han De-wu · 2017 · Molecular Medicine Reports
- Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex VivoFlora Mikaeloff, Marco Gelpi, Alejandra Escós, Tianqi Wang, Soham Gupta, Anna Olofsson, Sara Svensson Akusjärvi, Sabrina Schuster, Prajakta Naval, Vikas Sood et al. · 2025 · Advanced Science
- Signs of Alzheimer’s Disease: Tied to AgingJiahui Chen, Zhongying Zhu, Yuanyuan Xu · 2025 · International Journal of Molecular Sciences
- Microbiota and Alzheimer’s disease: mechanistic insights from a multi-organ perspectiveJiewen Liao, Hanmeng Mou, Shilin Luo, Lu Shen, Bin Jiao · 2026 · Translational Neurodegeneration
- Nanoparticle delivery for central nervous system diseases and its clinical applicationLin Tang, Rui Zhang, Yusi Wang, Mohan Liu, Die Hu, Yuanda Wang, Yang Li · 2024 · Nano Research
- The Role of Exosomes in the Pathogenesis, Diagnosis, and Treatment of Parkinson's and Alzheimer's DiseasesHamid Reza Moradi, Sahar Abdollahinezhad, Sohrab Heydarian · 2024 · The Neuroscience Journal of Shefaye Khatam
- The association between seizure predisposition and inflammation in a rat model of fatty liver diseaseDürdane Aksoy, Volkan Solmaz, Dilek Taşkıran, Oytun Erbaş · 2014 · Neurological Sciences
- Zyxin modulates the transmigration ofHaemophilus influenzaeto the central nervous systemYuko Miyazaki, Takashi Yusa, Saburo Matsuo, Yasuo Terauchi, Shuichi Miyazaki · 2014 · Virulence
- Future directions in ventilator-induced lung injury associated cognitive impairment: a new sightYinuo Liu, Xintong Cai, Ruiying Fang, Shengliang Peng, Wei Luo, Xiaohong Du · 2023 · Frontiers in Physiology
- Taraxacum coreanum (Korean Dandelion) Extract Protects Against Lipopolysaccharide-Induced Blood–Brain Barrier Destruction via Regulation of Tight Junctions and Inflammatory Responses in bEnd.3 CellsSeok Hee Han, Sang‐Hyun Lee, Hyun Young Kim, Ah Young Lee · 2024 · Journal of Medicinal Food
- Neuroprotection in Alzheimer’s DiseaseKewal K. Jain · 2011 · Humana Press eBooks
- Effect of simultaneous application of adenosine A1 receptor agonist and A2A receptor antagonist on memory, inflammatory factors, and PSD-95 in lipopolysaccharide-induced memory impairmentTahereh Ensandoust, Behrooz Khakpour-Taleghani, Adele Jafari, Mohammad Rostampour, Kambiz Rohampour, Mojtaba Hedayati · 2024 · Behavioural Brain Research
- Tualang honey and its methanolic fraction ameliorate lipopolysaccharide-induced oxidative stress, amyloid deposition and neuronal loss of the rat hippocampusWan Muhammad Hilmi Wan Yaacob, Idris Long, Rahimah Zakaria, Zahiruddin Othman · 2020 · Oriental Pharmacy and Experimental Medicine
- Glia dysfunction in schizophrenia: evidence of possible therapeutic effects of nervonic acid in a preclinical modelXiaona Wang, Jiacheng Fu, Huiying Wang, Cong Liu, Yongping Zhang, Cai Song, Changhong Wang · 2024 · Psychopharmacology
- Increased brain penetration of diphenhydramine and memantine in rats with adjuvant-induced arthritisAtsushi Kawase, Akira Kazaoka, Hiroaki Shimada, Masahiro Iwaki · 2021 · Brain Research
- Neuroprotection in Alzheimer DiseaseKewal K. Jain · 2019 · Springer protocols handbooks/Springer protocols
- Discovery of novel blood–brain barrier neuropathology in schizophrenia and bipolar disorder midbrainYunting Zhu, Gerardo Mendez Victoriano, Maree J. Webster, Frank A. Middleton, Paul T. Massa, Christine Fuller, Cynthia Shannon Weickert · 2026 · Brain Behavior and Immunity
- Porphyromonas gingivalis links Alzheimer’s disease and periodontal disease: Neuroinflammatory mechanisms and therapeutic implicationsSiyu Jin, Xing Wu, Yulong Zhang, Fei Xu, Wenyu Zhen, Yuqiang Sun, Yufei Pan, Yutong Lu, Ying Yang, Wansu Sun et al. · 2026 · hLife
- Elucidating molecular mechanisms governing tumor necrosis factor-alpha–mediated regulation of amyloid beta 42 uptake in blood-brain barrier endothelial cellsVrishali S. Salian, Geoffry L. Curran, Val J. Lowe, Xiaojia Tang, Krishna R. Kalari, Karunya K. Kandimalla · 2025 · Molecular Pharmacology
- Genomics-driven integrative analysis highlights immune-related plasma proteins for psychiatric disordersWeiming Gong, Ping Guo, Lu Liu, Ran Yan, Shuai Liu, Shukang Wang, Fuzhong Xue, Xiang Zhou, Xiubin Sun, Zhongshang Yuan · 2024 · Journal of Affective Disorders
- Exploring the Link Between Periodontitis and Alzheimer’s Disease—Could a Nanoparticulate Vaccine Break It?André Ferreira da Silva, Alexandra Gomes, Lídia Gonçalves, Adelaide Maria Afonso Fernandes, António José Almeida · 2025 · Pharmaceutics
- Microbial Trojan Horses: Virulence Factors as Key Players in Neurodegenerative DiseasesMatheus V. Coste Grahl, Kelvin Siqueira Hohl, Thiago Ângelo Smaniotto, Célia R. Carlini · 2025 · Molecules
- Neuropsychiatric Systemic Lupus Erythematosus: Mechanisms of InjuryMeggan C. Mackay, Aziz Müfit Uluğ, Bruce T. Volpe · 2011 · Elsevier eBooks
- Unraveling the Controversy: The Causal Link Between Osteoarthritis and Alzheimer's DiseaseJingkai Di, Yujia Xi, Yaru Liu, Likun Qi, Tingting Chen, Shuai Chen, Chuan Xiang · 2025 · Brain and Behavior
- Phospho-tau 181 is enhanced in saliva and plasma of edentulous patients: a first sign of dementia?Christine Zürcher, Michaela Defrancesco, Christian Humpel · 2025 · Frontiers in Oral Health
- The role of proteotoxic stress in vascular dysfunction in the pathogenesis of Alzheimer’s diseaseAna Catarina R. G. Fonseca, Rosa Resende, Sandra M. Cardoso, Cláudia Pereira · 2015 · Endoplasmic Reticulum Stress in Diseases
- The Blood-Brain BarriersWilliam A. Banks · 2016 · Springer eBooks
- Ferric Ammonium Citrate Reduces Claudin-5 Abundance and Function in Primary Mouse Brain Endothelial CellsPranav Runwal, Jae Pyun, Stephanie A. Newman, Celeste Mawal, Ashley Ian Bush, Liam M. Koehn, Joseph A. Nicolazzo · 2025 · Pharmaceutical Research
- Prolonged systemic inflammation worsens impairments to astrocyte Ca 2+ and functional hyperemia in Alzheimer's diseaseChang Liu, Kimia Sakha, Juni Anton, Alfredo Cárdenas‐Rivera, Mohammad Abbas Yaseen · 2026 · Alzheimer s & Dementia
- Inflammation and Microbiota and Gut ReconditioningStig Bengmark · 2017 · Wiley-VCH eBooks
- An easy-to-perform method for microvessel isolation and primary brain endothelial cell culture to study Alzheimer's diseaseYang Chen, Xiaomin Huang, Hui Chen, Chenju Yi · 2024 · Heliyon
- Mitochondrial Treatment Improves Cognitive Impairment Induced by Lipopolysaccharide in MiceQiu‐Qing Yan, Tianlong Liu, Lingling Liu, Yan‐Su Wei, Yuan‐Dan Zhao, Chao Yu, Zhen-Guo Zhong, Jin-Lan Huang, Deng‐Pan Wu · 2024 · Molecular Neurobiology
- Reduced oxycodone brain delivery in rats due to lipopolysaccharide-induced inflammation: microdialysis insights into brain disposition and sex-specific pharmacokineticsFrida Bällgren, Margareta Hammarlund‐Udenaes, Irena Loryan · 2024 · Fluids and Barriers of the CNS
- Neurotoxic effects of Cis-bifenthrin on microbe-gut-brain axis: Disruption of neurolipid balance in Xenopus laevisMeng Cathy Li, Chenxi Li, Mengai He, Liezhong Chen, Qiangwei Wang · 2025 · Ecotoxicology and Environmental Safety
- Neuroendocrine signaling as a pathological seed for the female bias of Alzheimer’s disease and the concept of estrobolomeDeepthi Rapaka, Arthur Saniotis, Thatayaone Monkgogi, Veera Raghavulu Bitra · 2026 · Biomedicine & Pharmacotherapy
- Mechanisms and Therapeutic Targeting of the Gut Microbiota-Immune-Brain Axis in Alzheimer’s DiseaseSiwen Wang, Xu Yuan, Tiantian Wang, Meng Yang, Peiliang Dong, Hua Han · 2026 · Immunological Investigations
- Is amyloid beta peptide a driver of inflammaging?Olga I. Kechko, Alexey A. Moskalev, Claudio Franceschi, Vladimir A. Mitkevich, Alexander А. Makarov · 2026 · Ageing Research Reviews
- Brain Aging and Cellular Senescence Trigger Neuroimmunological Dysregulation and NeurodegenerationAngélica Vega-García, Leticia Manuel Apolinar, Iris Angélica Feria-Romero, Patricia Campos‐Bedolla, Gutiérrez-García Carlos Alberto, Hiram Luna‐Munguía, Reyes-Huesca Sofía, Sandra Adela Orozco-Suárez · 2026 · Brain Sciences
- Disease Influence on BBB Transport in Inflammatory DisordersGeert J. Schenk, Gijs Kooij, Arie Reijerkerk, Helga E. de Vries · 2013 · AAPS advances in the pharmaceutical sciences series
- Computational Modeling of Phosphodiesterase Inhibitors as Anti-Alzheimer AgentsIoanna-Chrysoula Tsopka, Dimitra Hadjipavlou‐Litina · 2023 · Neuromethods
- Age-dependent sex differences in cofilin1 pathway (LIMK1/SSH1) and its association with AD biomarkers after chronic systemic inflammation in miceAmsha S. Alsegiani, Zahoor A. Shah · 2024 · Neurobiology of Aging
- Microglia in the Alzheimers brain: a help or a hindrance?Craig T. Vollert, Jason L. Eriksen · 2014 · AIMS neuroscience
- Gene Expression Analysis of the Human Astrocytoma Cell after Aβ25-35 Stimulation Followed by Ibuprofen AdministrationYoung-Sook Choi, Jungwoo Eun -, Suk‐Woo Nam, Sangho Kim M.D. td · 2011 · Journal of the Korean Geriatrics Society
- A potential role for LPS-induced inflammation in the induction of Alzheimer's disease-related pathology and cognitive deficitsMarielle S. Kahn · 2011
- Alleviation of central accumulation of amyloid-beta and prevention of cognitive dysfunction following peripheral inflammationMarielle Kahn Weintraub · 2014
- Coadministração de aminoácidos de cadeia ramificada e lipopolissacarídeo causam quebra da barreira hematoencefálicaMeline Oliveira dos Santos Morais · 2013
- Exposure of neonatal rats to alcohol has differential effects on cytokine levels in the cerebellum and hippocampus : potential role of microglia and astrocytesLauren A. Topper · 2015 · UNM’s Digital Repository (University of New Mexico)
- Diseases Mediated by the BBBWilliam A. Banks · 2013 · Elsevier eBooks
- Role of EPAC in axon determinationPablo Muñoz-LLancao · 2015
- Pathophysiology of the Blood–Brain Barrier in Neuroinflammatory DiseasesPetra Majerová, Andrej Kováč · 2017 · Springer eBooks
- Investigating anti-neuroinflammatory mechanism of orientin in lipopolysaccharide-induced BV2 microglia cellsPei Hong Gan, Anna Pick Kiong Ling, Kenny Voon, Rhun Yian Koh, Ying Pei Wong · 2019 · Asia-Pacific Journal of Molecular Biology and Biotechnology
- Compilação sobre possíveis biomarcadores para doença de AlzheimerMateus Ribeiro, Paulo Roberto Palma Urbano · 2020 · Revista Brasileira de Ciências Biomédicas
- Pharmacological Modulation of Toll-Like Receptors in Brain DisordersTahani K. Alshammari, Nouf Mohamed Al-Rasheed, Lina Alhushan, Reema Alhoutah, Anfal F. Bin Dayel, Asma S. Alonazi, Musaad A. Alshammari · 2021 · IntechOpen eBooks
- Effect of Diet Patterns in the Prevention of Alzheimer’s DiseaseDaniela S. Cosio, Suset Rodriguez, Arumugam Radhakrishnan Jayakumar, Michael John Paidas · 2023 · Nutritional neurosciences
- Host peripheral immune dynamics increase HIV-associated neurocognitive disorders incidence and progressionSamuel D. Johnson, Reema S. Guda, Narendra Kumar, Siddappa N. Byrareddy · 2024 · Elsevier eBooks
- The Blood–Brain BarriersWilliam A. Banks, Michelle A. Erickson · 2024 · Springer eBooks
- The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization studyQifan Zheng, Tong Xu, Shiyin Luo, Jiahui Zhao, Yue Ying, Nan Liu, Aijia Jiang, Yaping Pan, Dongmei Zhang · 2025 · Scientific Reports
- Additional file 1 of IL-6 from cerebrospinal fluid causes widespread pain via STAT3-mediated astrocytosis in chronic constriction injury of the infraorbital nerveNing Yu, Cui, Huan, Jin, Sixuan, Liu, Penghao, Fang, Yehong, Sun, Fengrun, Cao, Yan, Yuan, Bo, Yikuan Xie, Duan, Wanru et al. · 2024 · Figshare
- Additional file 1 of Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritisLai, Po-Hsuan, Wang, Ting-Hsuan, Zhang, Nai-You, Wu, Kuo-Chen, Yao, Chung-Chen Jane, Lin, Chun-Jung · 2021 · Figshare
- Additional file 2 of IL-6 from cerebrospinal fluid causes widespread pain via STAT3-mediated astrocytosis in chronic constriction injury of the infraorbital nerveNing Yu, Cui, Huan, Jin, Sixuan, Liu, Penghao, Fang, Yehong, Sun, Fengrun, Cao, Yan, Yuan, Bo, Xie, Yikuan, Duan, Wanru et al. · 2024 · Figshare
- Additional file 3 of IL-6 from cerebrospinal fluid causes widespread pain via STAT3-mediated astrocytosis in chronic constriction injury of the infraorbital nerveNing Yu, Cui, Huan, Jin, Sixuan, Liu, Penghao, Fang, Yehong, Sun, Fengrun, Cao, Yan, Yuan, Bo, Xie, Yikuan, Duan, Wanru et al. · 2024 · Figshare
- Adenosine Acts Through A2AR to Alleviate the Inflammatory Response Caused by Activation of Perivascular-Resident Macrophage-Like MelanocytesWenya Fan, Jiale null Lv, Lingling Neng, Bin null Zuo, Zhanjiang null Xu, B Chen, Jinhui null Zhang · 2025 · Frontiers in Bioscience-Landmark
- Linking peripheral low-grade inflammation and blood-cerebrospinal fluid barrier leakage in schizophrenia spectrum disorders – A retrospective analysisTimo Jendrik Faustmann, Aykut Aytulun, Armin Bahic, Michaela Jänner, Leonhard Schilbach, Daniel Kamp · 2026 · Brain Behavior & Immunity - Health
- The simultaneous effect of light/dark cycle and environmental enrichment on blood biomarkers in Alzheimer’s disease (AD)-like Neuroinflammation mouse modelBabak Pourgholamali, Hoora Ghovvati Choshal, Houri Hosseinalizadeh Seighalani, Behzad Pourgholamali, Armin Zahedi Abghari, Masoumeh Saberi Rounkian, Korosh Khanaki · 2026 · Neuroscience and Behavioral Physiology
- Intégrité de la barrière hémato-encéphalique et transport du peptide bêta-amyloïde dans la maladie d'AlzheimerTuan Minh Do · 2012 · theses.fr (ABES)
- Altérations lipidiques et homéostatiques dans les tissus nerveux associées au vieillissement et à des dérégulations métaboliques : implication du microbiote intestinal et de l’autophagieMayssa Albouery · 2020 · theses.fr (ABES)
- The Role of Inflammation in the Brain: A Gut-Driven PhenomenonNasir Uddin Mahbub, Md Minarul Islam, Seong Tshool Hong · 2026 · Springer eBooks
- Efficacy of Bacillus clausii as an adjuvant therapy in pathological neonatal unconjugated hyperbilirubinemia in the Nile Delta region of Egypt: a randomized controlled trialSamah S M Hussein, Sahar Mohamed El-Haggar, Sahar Kamal Hegazy, Mohamed Ahmed Rowisha · 2026 · Journal of Tropical Pediatrics
- The combined effects of probiotic and high-intensity interval training on memory function in high fat diet-fed ratsFarshad Karami, Fatemeh Shabkhiz, Soheila Adeli, Omid Reza Tamtaji, Michael Aschner, Shahnaz Halimi, Javad Fahanik‐Babaei, Fatemeh Nabavizadeh · 2026 · Behavioral and Brain Functions
- Metabolic endotoxemia in metabolic and neurodegenerative diseasesChangshun Li, Wei Jiang, Mingfang Lu · 2026 · Acta Biochimica et Biophysica Sinica
- In silico dysbiosis-associated neuroprotective metabolite insufficiency in Alzheimer’s diseaseNehad A. Shaer, Nouf S. Al-Abbas · 2026 · Open Medicine
- Beyond the brain-centric view: A systems physiology framework for exercise-induced neuroprotection in Alzheimer's diseaseWan Changjian, Wang Furui, Fan Yanyu, Yang Yü, Jianshe Wei · 2026 · Experimental Neurology
- Gut Microbiota Modulation in CNS Disorders: Therapeutic Strategies and Implications for Drug EfficacyLamiaa A. Ahmed, Khaled F. Al‐Massri · 2026 · Molecular Neurobiology
- Structural network alterations and peripheral immune-inflammatory dysregulation define distinct subtypes of major depressive disorder with prognostic implicationsWei Du, Minlan Yuan, Ziyang Gao, Haoran Li, Weijie Xue, Guyue Lei, Erqing Liao, Daniel J. Hauke, Yalan Kuang, Danlin Shen et al. · 2026 · Psychological Medicine
- The Glymphatic–Meningeal Lymphatic System and Autophagy in ME/CFS and Long COVID: A Mechanistic PerspectiveMohsen Nemat‐Gorgani, Michael A. Jensen, Ronald Wayne Davis · 2026 · International Journal of Molecular Sciences