Inflammatory markers in depression: A meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls

Osimo, Emanuele F.; Pillinger, Toby; Rodriguez, Irene Mateos; Khandaker, Golam M.; Pariante, Carmine M.; Howes, Oliver D.

doi:10.1016/j.bbi.2020.02.010

Inflammatory markers in depression: A meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls

Highlights • Patients with depression show reduced variability in pro-inflammatory immune measures.• Patients with depression show increases in pro-inflammatory immune markers mean levels, and reductions in anti-inflammatory IL-4.