Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson’s disease via gut microbiota-GLP-1 pathway

Sun, Jing, Li, Haijun, Jin, Yangjie, Yu, Jiaheng, Mao, Shiyin, Su, Kuan-Pin, Ling, Zongxin, Liu, Jiaming·2021·Brain, Behavior, and Immunity
DOI 10.1016/j.bbi.2020.10.014

Cited by (262)

Items 101–200 of 262

  1. Chronic Treatment with the Probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis BB12 Attenuates Motor Impairment, Striatal Microglial Activation, and Dopaminergic Loss in Rats with 6-Hydroxydopamine-induced Hemiparkinsonism
    Sergio Guillermo Cuevas-Carbonell, Lizbeth Vásquez-Celaya, Daniel García-López, Diego Granados-Patrón, María del Rosario García‐Miss, Fernando J. Álvarez-Cervera, Mirza Mut-Martı́n, Irving Parra, Liliana Mendieta, Humberto Salgado et al. · 2022 · Neuroscience
  2. Risk of Parkinson disease associated with pesticide exposure and protection by probiotics
    Neelu Kanwar Rajawat, Kanika Bhardwaj, Nupur Mathur · 2022 · Materials Today Proceedings
  3. The Role of an Altered Gut Microbiome in Parkinson’s Disease: A Narrative Review
    Sara A. Hashish, Mohamed Salama · 2023 · Applied Microbiology
  4. Mechanisms of probiotic modulation of ovarian sex hormone production and metabolism: a review
    Xiao dong Liu, Xiaoyong Chen, Chen Wang, Jiajia Song, Jiahui Xu, Zhen Gao, Yechuan Huang, Huayi Suo · 2024 · Food & Function
  5. Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity
    Anatoly V. Skalny, Michael Aschner, В. А. Гриценко, Airton C. Martins, Yousef Tizabi, Tatiana V. Korobeinikova, Mônica Maria Bastos Paoliello, Alexey A. Tinkov · 2024 · Advances in neurotoxicology
  6. Parkinson Disease and the Gut: A Primer for Gastroenterologists
    Amol Sharma, Robin M. Voigt, Christopher G. Goetz, Ali Keshavarzian · 2025 · The American Journal of Gastroenterology
  7. Microbiota- Brain-Gut-Axis Relevance to Parkinson’s Disease: Potential Therapeutic Effects of Probiotics
    Khadga Raj, Shamsher Singh, Shivani Chib, Sudhanshu Mallan · 2022 · Current Pharmaceutical Design
  8. Acanthopanax senticosus Harms improves Parkinson's disease by regulating gut microbial structure and metabolic disorders
    Yi Lu, Xin Gao, Nan Yang, Shadi A. D. Mohammed, Jiaqi Fu, Tianyu Wang, Chong‐Zhi Wang, Chun‐Su Yuan, Fang Lu, Shumin Liu · 2023 · Heliyon
  9. Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction
    Yangxia Li, Qing Tong, Ye Wang, Yue Cheng, Yao Geng, Tian Tian, Yongsheng Yuan, Yi Fan, Ming Lu, Kezhong Zhang · 2024 · Cell Death Discovery
  10. Lactiplantibacillus plantarum SG5 inhibits neuroinflammation in MPTP-induced PD mice through GLP-1/PGC-1α pathway
    Yueyan Qi, Yuxuan Dong, Jinhu Chen, Siyou Xie, Xin Ma, Xueping Yu, Yang Yu, Yanqin Wang · 2024 · Experimental Neurology
  11. Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study
    Jiayu Tu, Jun Zhang, Gang Chen · 2025 · Frontiers in Aging Neuroscience
  12. Toward Elucidating the Human Gut Microbiota–Brain Axis: Molecules, Biochemistry, and Implications for Health and Diseases
    Yunjia Lai, Radhika Dhingra, Zhenfa Zhang, Louise M. Ball, Mark J. Zylka, Kun Lü · 2021 · Biochemistry
  13. RETRACTED ARTICLE: lncRNA NEAT1 promotes autophagy of neurons in mice by impairing miR-107-5p
    Dong Li, Yumin Zheng, Xiaoguang Luo · 2022 · Bioengineered · Retracted
  14. Effect of Probiotics Supplementation on REM Sleep Behavior Disorder and Motor Symptoms in Parkinson's Disease: A Pilot Study
    Yitong Du, Lin Wang, Ying Cui, Xiaojiao Xu, Mingkai Zhang, Yue Li, Ting Gao, Dan Gao, Zhi Sheng, Shiya Wang et al. · 2025 · CNS Neuroscience & Therapeutics
  15. Parkinson’s disease and the gut-brain connection: unveiling pathways, mechanisms and promising therapies
    Suhas Hajare, Yogesh Anant Kulkarni · 2025 · Brain Research
  16. Designing lisuride intranasal nanocarrier system for reduction of oxidative damage with enhanced dopamine level in brain for Parkinsonism
    Shobhit Kumar, Satish Kumar Gupta, Rakesh Pahwa · 2023 · Journal of Psychiatric Research
  17. Dietary Clostridium butyricum and 25-Hydroxyvitamin D3 modulate bone metabolism of broilers through the gut—brain axis
    Guangtian Cao, Yang Yu, Huixian Wang, Huijuan Yang, Fei Tao, Shenglan Yang, Jinsong Liu, Zhanming Li, Caimei Yang · 2024 · Poultry Science
  18. Metabonomics Combined with 16S rRNA Gene Sequencing to Analyze the Changes of Gut Microbiota in Mice with Parkinson's Disease and the Intervention Effect of Cyanidin-3-O-Glucoside
    Wang Wang, Guoxue Zhu, Yuwen Wang, Wei Li, Shilin Yi, Kai Wang, Lu Fan, Juanjuan Tang, Ruini Chen · 2022 · Frontiers in Aging Neuroscience
  19. Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway: a potential therapeutic approach for neurodegenerative diseases
    Fengcheng Deng, Dan Yang, Lingxi Qing, Yifei Chen, Jilian Zou, Meiling Jia, Qian Wang, Runda Jiang, Huang Li-hua · 2024 · Neural Regeneration Research
  20. Microbial SCFAs as epigenetic mediators: fine-tuning the gut-brain axis in neurodegenerative disorders
    Xiaocui Xu, Yiwen Cheng, Xia Liu, Wenwen Ding, Zhangcheng Zhu, Lingbin Wu, Zongxin Ling, Yongtao Gao, Yue Jing · 2026 · Current Research in Microbial Sciences
  21. Effects of Gut Microbiota Alterations on Motor, Gastrointestinal, and Behavioral Phenotype in a Mouse Model of Parkinson’s Disease
    Nina Radisavljevic, Mihai S. Cirstea, Kylynda C. Bauer, Christine Lo, Avril Metcalfe‐Roach, Tahereh Bozorgmehr, Haggai Bar‐Yoseph, B. Brett Finlay · 2022 · Journal of Parkinson s Disease
  22. Compound Dihuang Granule Changes Gut Microbiota of MPTP-Induced Parkinson’s Disease Mice via Inhibiting TLR4/NF-κB Signaling
    Zhu-qing He, Peng-fei Huan, Li Wang, Jiancheng He · 2023 · Neurochemical Research
  23. Clostridium butyricum Alleviates DEHP Plasticizer-Induced Learning and Memory Impairment in Mice via Gut–Brain Axis
    Jin Wang, Feng Qiu, Zilong Zhang, Yu Liu, Qian Zhou, Siyu Dai, Shuanglin Xiang, Chenxi Wei · 2023 · Journal of Agricultural and Food Chemistry
  24. Study on the mechanism of gut microbiota in the pathogenetic interaction between depression and Parkinson 's disease
    Peiyun Zhang, Wei Jin, Zhaoshun Lyu, Xinxuan Lyu, Lihong Li · 2024 · Brain Research Bulletin
  25. Glycyrrhiza uralensis Fisch. and its active components mitigate Semen Strychni-induced neurotoxicity through regulating high mobility group box 1 (HMGB1) translocation
    Xiaoyu Duan, Jing Wen, Min Zhang, Chao Wang, Yalan Xiang, Lu Wang, Changwei Yu, Gongying Deng, Miao Yan, Bikui Zhang et al. · 2022 · Biomedicine & Pharmacotherapy
  26. Targeted Liposomal Co-Delivery Dopamine with 3-n-Butylphthalide for Effective Against Parkinson’s Disease in Mice Model
    Yi Liang, Liping Feng, Yue Zheng, Yunzhen Gao, Rongying Shi, Zhirong Zhang, Xue Ying, Yingchun Zeng · 2024 · International Journal of Nanomedicine
  27. Exploring the role of gut microbiota in Parkinson’s disease: insights from fecal microbiota transplantation
    Mengqi Guo, Han Gao, Yuan Wang, Yuanyuan Xiang · 2025 · Frontiers in Neuroscience
  28. Central neuropeptides as key modulators of astrocyte function in neurodegenerative and neuropsychiatric disorders
    Mengjie Yang, Min Jia, Meng Cai, Xiao Feng, Lining Huang, Jianjun Yang · 2025 · Psychopharmacology
  29. Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review
    Mohamed T. El‐Saadony, Ahmed M. Saad, Mahmoud Zaki Sitohy, Samar Sami Alkafaas, Mthokozisi Dladla, Soumya Ghosh, Dina Mostafa Mohammed, Essam H. Ibrahim, Mohamed A. Fahmy, Amr Elkelish et al. · 2026 · Frontiers in Immunology
  30. The Interaction Between Nutraceuticals and Gut Microbiota: a Novel Therapeutic Approach to Prevent and Treatment Parkinson’s Disease
    Liyan Yao, Yong Yang, Xiaowei Yang, Mohammad J. Rezaei · 2024 · Molecular Neurobiology
  31. Gut microbiota and Parkinson’s disease: potential links and the role of fecal microbiota transplantation
    Maosen Feng, Zhiyan Zou, Pingping Shou, Wei Peng, Mingxue Liu, Xiaoan Li · 2024 · Frontiers in Aging Neuroscience
  32. Maturation, Morphology, and Function: The Decisive Role of Intestinal Flora on Microglia: A Review
    Lichao Liu, Fan Tong, Huanhuan Li, Yawen Bin, Peng Ding, Ling Peng, Zhiwei Liu, Xiaorong Dong · 2023 · Journal of Integrative Neuroscience
  33. Disrupting the Gut–Brain Axis: How Artificial Sweeteners Rewire Microbiota and Reward Pathways
    Roberto Coccurello · 2025 · International Journal of Molecular Sciences
  34. Promising biomarkers and therapeutic targets for the management of Parkinson's disease: recent advancements and contemporary research
    Mohammad Ahmed Khan, Nafis Haider, Tanveer Singh, Ritam Bandopadhyay, Mohammed M. Ghoneim, Sultan Alshehri, Murtada Taha, Javed Ahmad, Awanish Mishra · 2023 · Metabolic Brain Disease
  35. The Microbiome–Neurodegeneration Interface: Mechanisms, Evidence, and Future Directions
    Lilia Böckels, Daniel Alexa, Dorin Cristian Antal, Cristina Gațcan, Cosmin Alecu, Kristina Kacani, Raul Andrei Cretu, Emanuel-Andrei Piseru, Robert Valentin Bîlcu, Dan Iulian Cuciureanu · 2026 · Cells
  36. New Pieces for an Old Puzzle: Approaching Parkinson’s Disease from Translatable Animal Models, Gut Microbiota Modulation, and Lipidomics
    Lorena Ortega Moreno, Ana Bagüés, Vicente Martínez, Raquel Abalo · 2023 · Nutrients
  37. Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease
    Pranay Srivastava, Shuhei Nishiyama, Fang Zhou, Sonia Lin, Akriti Srivastava, Chien‐Wen Su, Yuehang Xu, Weiyi Peng, Michael Levy, Michael A. Schwarzschild et al. · 2023 · Journal of Neuroimmune Pharmacology
  38. Effects of an Akt-activating peptide obtained from walnut protein degradation on the prevention of memory impairment in mice
    Like Lin, Cong Li, Yujiao Zhang, Li Zhang, Lu Gao, Lihua Jin, Yu Shu, Yehua Shen · 2024 · Food & Function
  39. Gut-directed therapy in Parkinson’s disease
    Laura Benvenuti, Clelia Di Salvo, Gabriele Bellini, Luisa Seguella, Francesco Rettura, Giuseppe Esposito, Luca Antonioli, Roberto Ceravolo, Nunzia Bernardini, Carolina Pellegrini et al. · 2024 · Frontiers in Pharmacology
  40. The Intricate Interplay: Microbial Metabolites and the Gut‐Liver‐Brain Axis in Parkinson's Disease
    Dayamrita Kollaparampil Kishanchand, Athira Krishnan K. A., Krishnapriya Chandrababu, Cyriac Abby Philips, Unnikrishnan Sivan, P. S. Baby Chakrapani · 2025 · Journal of Neuroscience Research
  41. The role of the gut microbiota in neuropsychiatric disorders and therapy
    Fan Zhang, Kang Ding, Linmei Zhang, Dongyao Liu, Xin Dong, Man‐Ni Wang, Fu-Lin Zhou, Yi‐Wei Sun, Wei‐Ku Zhang, Yan Yu et al. · 2025 · Ageing Research Reviews
  42. Gut-oriented disease modifying therapy for Parkinson's disease
    Chin‐Hsien Lin, Hsin‐Chih Lai, Ming‐Shiang Wu · 2022 · Journal of the Formosan Medical Association
  43. Association between neutrophil-to-lymphocyte ratio and motor subtypes in idiopathic Parkinson’s disease: a prospective observational study
    Hongyan Yi, Xiaojing Liang, Fugui Xu, Tiantian Li, Xiu Yang, Ming Wei, Zhou Ou, Lijun Wang, Qiang Tong · 2024 · BMC Neurology
  44. From-Toilet-to-Freezer: A Review on Requirements for an Automatic Protocol to Collect and Store Human Fecal Samples for Research Purposes
    Frances Widjaja, Ivonne M.C.M. Rietjens · 2023 · Biomedicines
  45. TAT‐LBD‐Ngn2‐improved cognitive functions after global cerebral ischemia by enhancing neurogenesis
    Bin Feng, Sansan Jia, Liya Li, Jiajia Wang, Fang Zhou, Xingchun Gou, Qiang Wang, Lize Xiong, Yi Zeng, Haixing Zhong · 2022 · Brain and Behavior
  46. Prebiotics and probiotics and Parkinson's disease
    Reza Amani, Sanaz Mehrabani · 2023 · Elsevier eBooks
  47. Advice to People with Parkinson’s in My Clinic: Probiotics and Prebiotics
    Jia Wei Hor, Tzi Shin Toh, Shen‐Yang Lim, Ai Huey Tan · 2024 · Journal of Parkinson s Disease
  48. The therapeutic effects and mechanisms of glucagon-like peptide-1 receptor agonists in neurocognitive disorders
    Junchen Si, Kai Yu, Jiheng Hao, Jiyue Wang, Liyong Zhang · 2025 · Therapeutic Advances in Neurological Disorders
  49. Tim-3 Deficiency Ameliorates Motor Deficits and Neuroinflammation in MPP+/MPTP-Induced Parkinson’s Disease Models via the NF-κB/NLRP3 Pathway
    Xi Yin, Ge Li, Fei Ji, Miao Wang, Yang Gao, Fengzhu Li, Zhenfu Wang, Gencheng Han, Zhongbao Gao · 2024 · Molecular Neurobiology
  50. Treadmill intervention attenuates motor deficit with 6-OHDA-induced Parkinson’s disease rat via changes in lipid profiles in brain and muscle
    Binar Panunggal, Tu‐Hsueh Yeh, Shu‐Ping Tsao, Chun Pan, Wei-Ting Shih, Ya‐Tin Lin, Amelia Faradina, Chia‐Lang Fang, Hui-Yu Huang, Shih‐Yi Huang · 2025 · Aging
  51. Clostridium butyricum JJ100 and Lacticaseibacillus rhamnosus LR alleviate liver injury in mice caused by continuous high-dose-alcohol exposure by protecting the intestinal barrier, rebuilding the gut microbiota and regulating AMPK and TLR4/NF-κB signaling pathways
    Yonghao Hu, Yujie Wang, Xudong Li, Qiong Xie, Zhitang Lyu · 2025 · Food & Function
  52. SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of vidarabine against rotenone-induced neural cell injury
    Lanxin Li, Yang Zhang, Zhengqian Chen, Ruyong Yao, Zhongqiu Xu, Can Xu, Fujie He, Haitao Pei, Cui Hao · 2023 · Heliyon
  53. Microglia are necessary for probiotics supplementation to improve impaired fear extinction caused by pregnancy stress in adult offspring of rats
    Ru Zeng, Jie Chen, Yihan Peng, Weiye Xu, Yuanyuan Tao, Min Li, Ru-Qi Zhang, Jingzhuo Meng, Zhiyuan Li, Leping Zeng et al. · 2023 · Neurobiology of Stress
  54. Brazilin-Rich Extract from Caesalpinia sappan L. Attenuated the Motor Deficits and Neurodegeneration in MPTP/p-Induced Parkinson’s Disease Mice by Regulating Gut Microbiota and Inhibiting Inflammatory Responses
    Wen Gao, Xinni Wu, Yang Wang, Fuping Lu, Fufeng Liu · 2024 · ACS Chemical Neuroscience
  55. Differences in Physiological Performance and Gut Microbiota between Deep-Sea and Coastal Aquaculture of Thachinotus Ovatus: A Metagenomic Approach
    Shuangfei Li, Shilin Wang, Cong Pan, Yanqing Luo, Shitong Liang, Siru Long, Xuewei Yang, Boyu Wang · 2023 · Animals
  56. Diet, gut-brain axis, and metabolism-epigenome-immunity networks: A triad in neurological disease management
    Yishu Fan, Bo Xiao, Hong‐Hao Zhou, Zhaoqian Liu, Leli Wang, Weilin Jin, Yulong Yin, Xiao‐Yuan Mao · 2025 · Pharmacological Research
  57. Microbial Metabolites and the Gut-Brain Axis in Neurological Disorders: Implications for Neuropharmacology and Therapy
    Yuchen Wang, Yang Zhang · 2025 · Neuropharmacology and Therapy
  58. The human-derived novel gut commensal Luoshenia tenuis regulates body weight and food intake in mice
    Yu Jiang, Meng‐Xuan Du, Lisheng Xie, Min-Zhi Jiang, Yaokun Zhang, Mingxia Bi, Chang Liu, Hongwei Liu, Shuang‐Jiang Liu · 2023 · Food Science and Human Wellness
  59. Deciphering the microbial map and its implications in the therapeutics of neurodegenerative disorder
    Shrutikirti Vashishth, Rashmi K. Ambasta, Pravir Kumar · 2024 · Ageing Research Reviews
  60. The role of gut-derived short-chain fatty acids in Parkinson's disease
    Mohamed Jamal Saadh, Anfal Nabeel Mustafa, Mohammed Ahmed Mustafa, Renuka Jyothi S, Hasan Khalid Dabis, G. V. Siva Prasad, Imad Jassim Mohammad, Ahmed Adnan, Ameer Hassan Idan · 2024 · Neurogenetics
  61. Human-fecal microbiota transplantation in relation to gut microbiome signatures in animal models for schizophrenia: A scoping review
    Raghunath Singh, Kristoffer J. Panganiban, Emily Au, Rekha Ravikumar, Sandra Pereira, Thomas D. Prévot, Daniel J. Müller, Gary J. Remington, Sri Mahavir Agarwal, Elena Francisca Verdu et al. · 2024 · Asian Journal of Psychiatry
  62. Gut: The gate and key to brain
    Xiaohan Zhang, Yunsheng Yang · 2025 · Chinese Medical Journal
  63. GLP-1/GIP dual agonist tirzepatide alleviates mice model of Parkinson's disease by promoting mitochondrial homeostasis
    Ruixue Tian, Kexin Liu, Hurong Lai, Caifeng Liao, Jian Li, Huaijun Tu · 2025 · International Immunopharmacology
  64. TREM‐1 Promotes Microglial Pyroptosis and Mitochondrial Fission in Intracerebral Hemorrhage via the PI3K/AKT Pathway
    Yuan An, Tingting Zhai, Fang Wang, Kaiyuan Zhang, Mengzhao Feng, Dengpan Song, Zhihua Li, Fuyou Guo · 2025 · The FASEB Journal
  65. Progressive Hippocampal Neuroarchitecture Changes in the 5×FAD Alzheimer’s Disease Mouse Model
    Hyewon Jang, Sueun Lee, Yeong-Jun Kim, Jeongmin Lee, Sang-Won Kim, Yeonghoon Son, Joong‐Sun Kim, Jong‐Hwan Park, BuHyun Youn, Changjong Moon · 2025 · Journal of Integrative Neuroscience
  66. Sulfur amino acids, metabolic health and beyond: Recent advances, translational implications, and future research considerations
    Thomas Olsén, Amany K. Elshorbagy, Jay E. Johnson, Sailendra Nath Nichenametla, Zhen Dong, Kumar Sambamurti, John P. Richie, Kathrine J. Vinknes · 2025 · Analytical Biochemistry
  67. The giant panda gut harbors a high diversity of lactic acid bacteria revealed by a novel culturomics pipeline
    Wenping Zhang, Lijun Zheng, Junjin Xie, Xiaoyan Su, Mingchun Zhang, He Huang, Stephan Schmitz‐Esser, Shizhang Du, Yu Yang, Jiqin Xie et al. · 2024 · mSystems
  68. The Associations Among Gut Microbiota, Branched Chain Amino Acids, and Parkinson’s Disease: Mendelian Randomization Study
    Zhenzhen Yan, Guohua Zhao · 2024 · Journal of Parkinson s Disease
  69. Disease modifying therapies for Parkinson's disease: Novel targets
    Nirosen Vijiaratnam, Thomas Foltynie · 2021 · Neuropharmacology
  70. IRAK-M deficiency exacerbates dopaminergic neuronal damage in a mouse model of sub-acute Parkinson’s disease
    Yidong Deng, Yuangao Liao, Peijian Huang, Yujian Yao, Weihua Liu, Yong Gu, Guohu Weng · 2023 · Neuroreport
  71. Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway
    Yueyan Qi, Siyou Xie, Jinhu Chen, Cancan Zhang, Xin Ma, Yu Pu Yang, Xueping Yu, Yanqin Wang · 2025 · The Journal of Nutritional Biochemistry
  72. Pharmacological and electrophysiological characterization of the novel Kv7 channel inhibitor racecadotril in Parkinson's disease
    Bo Yang, Hui Liu, Shifan Zhang, Biao Liu, Qiaoqiao Sun, Wen Li, Rong Zheng, Qingzhuo Cui, Yulin Gu, Xiaoke Li et al. · 2025 · Neuropharmacology
  73. New perspectives on key bioactive molecules of lactic acid bacteria: integrating targeted screening, key gene exploration and functional evaluation
    Shi Hu, Qi Wang, Jinfeng Wu, Hangjia Zhang, Jiaqi Yin, Lina Ding, Ping Li, Hang Xiao, Qing Gu, Jia‐Run Han · 2025 · Critical Reviews in Food Science and Nutrition
  74. Nano-magnetoelectric biomimetic system promotes neural differentiation and reverses dopaminergic neuron damage for Parkinson's disease therapy
    Jie Zhang, Jiahui Shi, Qiubo Yang, Haogang Guo, Lingfeng Guo, Guoliang Zhou, Yinyi Liu, Xiaolei Wang, Xian Hao, Yifei Yang · 2025 · Chemical Engineering Journal
  75. Biomimetic nanodelivery system with simultaneous blood–brain barrier-crossing and neuroprotective abilities for anti-parkinsonian therapy
    Xuanying Yin, Jinmei Qiu, Guowang Cheng, Jiaxin Wu, Chen Wang, Chunye Zheng, Shuiqing Huang, Tongkai Chen · 2025 · Chinese Medicine
  76. Mechanistic Interplay of Gut Microbiota and Blood–Brain Barrier Integrity in Neurodegenerative Diseases
    Suleiman Ibrahim Mohammad, Yasir Mohammed Hammood, Asokan Vasudevan, Subasini Uthirapathy, Suhas Ballal, A. Sabarivani, Swati Mishra, Deepak Nathiya, Zahraa Haleem Al‐qaim, Abed Jawad KADHIM · 2025 · Molecular Neurobiology
  77. Neuroprotective effects of ZiYin XiFeng formula against Parkinson's disease via Nrf2/SLC7A11/GPX4-mediated ferroptosis inhibition
    Xiangyu Guo, Qiang Fu, Bowen Pang, Huihan He, Ge Yang · 2025 · Journal of Ethnopharmacology
  78. Probiotic: A Gut Microbiota-Based Therapeutic Approaches for the Treatment of Parkinson’s Disease
    Monalisa Rout, Shakti Ketan Prusty, Durga Madhab Kar · 2024 · Current Clinical Pharmacology
  79. Molecular insights into Parkinson's disease and type 2 diabetes mellitus: Metformin's role and genetic pathways explored
    Tingting Liu, Haojie Wu, Jianshe Wei · 2025 · Experimental Neurology
  80. Altered Gut Microbiota as an Auxiliary Diagnostic Indicator for Patients With Fracture-Related Infection
    Xingqi Zhao, Wenli Tang, Haoyang Wan, Zixin Lan, Hanjun Qin, Qing‐rong Lin, Yanjun Hu, Guangchuang Yu, Nan Jiang, Bin Yu · 2022 · Frontiers in Microbiology
  81. Interaction Between Natural Products and Gut Microbiota
    Duygu Ağagündüz, Özge Cemali, Elif Çelik · 2022 · Current Pharmacology Reports
  82. Probiotic Influences on Motor Skills: A Review
    Robert Lalonde, C. Strazielle · 2023 · Current Neuropharmacology
  83. Bile acids as therapeutic agents
    Brandon Vu, Ryo Kawamoto, Priscila Villalba‐Davila, Xinzhong Dong, Wikrom W. Karnsakul · 2026 · Frontiers in Pharmacology
  84. Randomized clinical trial to test the safety and tolerability of SBD111, an optimized synbiotic medical food combination designed for the dietary management of the metabolic processes underlying osteopenia and osteoporosis
    Shivani Sahni, Eric M. Schott, Danette Carroll, Maria Juliana Soto-Girón, Susan Corbett, Gerardo V. Toledo, Douglas P. Kiel · 2023 · Journal of Microbiology & Experimentation
  85. The Ang-(1–7)/MasR axis ameliorates neuroinflammation in hypothermic traumatic brain injury in mice by modulating phenotypic transformation of microglia
    Dan Ye, Jiamin Liu, Long Lin, Pengwei Hou, Tianshun Feng, Shousen Wang · 2024 · PLoS ONE
  86. Peroxisome Proliferator-Activated Receptors (PPARs) May Mediate the Neuroactive Effects of Probiotic Metabolites: An In Silico Approach
    Irving Parra, Alan Carrasco‐Carballo, Victoria Palafox-Sánchez, Isabel Martínez-García, José Aguilera, José Luis Góngora-Alfaro, Irma Isela Aranda-González, Yousef Tizabi, Liliana Mendieta · 2025 · International Journal of Molecular Sciences
  87. Soy isoflavones mitigate atrazine-induced dopaminergic neuron damage via reshaping short-chain fatty acid-producing bacteria in gut microbiota and modulating the GPR43/GLP-1/GLP-1R axis
    Yinan Zhang, Qilei Chen, Yaning Xu, Yanming Lv, Yini Wang, Xin-yu Shi, Jiaqi Liu, Jie Wen, Xueting Li, Baixiang Li · 2025 · Ecotoxicology and Environmental Safety
  88. Esketamine relieves depressive-like behaviors in MPTP-induced Parkinson disease mice via GPR109A-dependent reduction of neuroinflammation
    Shu Wang, Wei Song, Yuanyuan Gao, Wei Tan, Lin Ji, Chen Wang · 2025 · Brain Research Bulletin
  89. Therapeutic role of probiotics in motor and non-motor symptoms of Parkinson’s disease
    Salomón Páez‐García, Daniel Hernández-Triana, Félipe Esparza Salazar, George Emilio Barreto, María Cruz Rodríguez-Oroz, Miguel Germán Borda · 2025 · Exploration of Neuroprotective Therapy
  90. From dysbiosis to dysfunction: specific gut microbes and metabolites in the pathogenesis of Parkinson’s disease
    Fang Chi, Kun Chen, Yue Yin, Janetta R. Hakovirta, Per E. J. Saris · 2026 · Sustainable Microbiology
  91. Neuroprotective effects and mechanism of ginseng aqueous extract against Alzheimer’s disease
    Xiaohan Zhang, Kailing Cao, Junqing Wan, Zhifu Liu, Zhiyang Ren, Wenjie Wang, Hao Wang · 2026 · Phytomedicine
  92. Prebiotics attenuate depressive-like behavior, neuroinflammation and synaptic plasticity in Parkinson’s disease by modulating butyrate-producing gut bacteria
    Ingrid Prata Mendonça, Rodrigo Soares da Silva, Igor Henrique Rodrigues de Paiva, Belmira Lara da S. A. Costa, Karla Patrícia de Sousa Barbosa Teixeira, José Roberto Botelho de Souza, Christina Alves Peixoto · 2026 · Inflammopharmacology
  93. Energy metabolic failure drives the selective degeneration of dopaminergic neurons in Parkinson’s disease
    Zhipeng Zhou · 2026 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  94. Probiotics and Prebiotics: Meeting Dietary Requirements for Optimal Health and Planetary Sustainability
    Juan Chen, Yifei Yu, Siyuan Sun, Weiru Yu, Yumei Lei, Chenya Lu, Jianan Zhai, Feirong Bai, Fazheng Ren, Ran Wang · 2025 · Journal of Nutrition
  95. Food for thought: probiotic modulation of microglial activity in Parkinson's disease
    Isabella Kroker Kimber, Marie‐Ève Tremblay · 2025 · Frontiers in Molecular Neuroscience
  96. Lactobacilli Probiotics Prevent Amyloid-Beta Fibril Formation In Vitro
    Sanaa Harrass, Michael Quansah, Sachin Kumar, Michael Radzieta, Bhawantha M. Jayawardena, Christopher E. Jones, Monique Antoinette David, Benjamin Heng, Liam D. H. Elbourne, Seth Dortey Amanquah et al. · 2025 · Probiotics and Antimicrobial Proteins
  97. Microbiome-Based Therapies in Parkinson’s Disease: Can Tuning the Microbiota Become a Viable Therapeutic Strategy?
    Adejoke Y. Onaolapo, Folusho O. Ojo, Anthony Tope Olofinnade, Joshua Falade, Ismail Adetayo Lawal, Olakunle J. Onaolapo · 2022 · CNS & Neurological Disorders - Drug Targets
  98. Upregulation of cAMP/PKA/CREB signaling mediated by GABABR might contribute to the amelioration effects of sea cucumber peptides (Acaudina leucoprocta) on cognitive dysfunction in mice
    Qianqian Wang, Junhui Zhang, Yue Wu, Minjie Zhao, Jing Wang, Juan Du, Zhongyan Bao, Weihong Min, Fei Shen, Fengqin Feng · 2024 · Food Bioscience
  99. Ginkgolide B ameliorates MPTP-induced neuroinflammation and neurodegeneration by improving mitochondrial electron transport chain complex I
    Irene Mary Praveen, Vigil S Anbiah, Calivarathan Latchoumycandane · 2025 · Journal of Cellular Neuroscience and Oxidative Stress
  100. OTUD6A drives dopaminergic neuronal degeneration of Parkinson's disease through deubiquitinating ACTG1 in neuronal cells
    Xia Zhao, Fan Chen, Xiong Li, Xiaoxia Xu, Ziyao Meng, Yu Deng, Qi Ai, Luyao Li, Qin Yu, Linjie Chen et al. · 2025 · Acta Pharmaceutica Sinica B