Efficacy and safety of Lacticaseibacillus paracasei Lpc-37® in students facing examination stress: A randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study)

Mäkelä, Sanna M.; Griffin, Síle M.; Reimari, Jenni; Evans, Kara C.; Hibberd, Ashley A.; Yeung, Nicolas; Ibarra, Alvin; Junnila, Jouni; Turunen, Jari; Beboso, Ronnie; Chhokar, Balgit; Dinan, Timothy G.; Cryan, John; Patterson, Elaine

doi:10.1016/j.bbih.2023.100673

Efficacy and safety of Lacticaseibacillus paracasei Lpc-37® in students facing examination stress: A randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study)

Lacticaseibacillus paracasei Lpc-37 (Lpc-37) has previously shown to reduce perceived stress in healthy adults. The ChillEx study investigated whether Lpc-37 reduces stress in a model of chronic examination stress in healthy students. One hundred ninety university students (18–40 y) were randomiz…