The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells
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Hepatocyte sortilin modulates very low density lipoprotein (VLDL) secretion.
“In addition to facilitating PCSK9 secretion, hepatocyte sortilin has been shown to modulate very low density lipoprotein (VLDL) secretion;66–70”
From EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis (2025) · cites this paper as [67]
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Cites
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
Musunuru, K., Strong, A., Frank-Kamenetsky, M., Lee, N. E., Ahfeldt, T., Sachs, K. V., Li, X., Li, H., Kuperwasser, N., Ruda, V. M., et al. (2010) · Nature · doi:10.1038/nature09266 · Cited by 1,140
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism
Strong, A., Ding, Q., Edmondson, A. C., Millar, J. S., Sachs, K. V., Li, X., Kumaravel, A., Wang, M. Y., Ai, D., Guo, L., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci63563 · Cited by 222
Macrophage Sortilin Promotes LDL Uptake, Foam Cell Formation, and Atherosclerosis
Patel, K. M., Strong, A., Tohyama, J., Jin, X., Morales, C. R., Billheimer, J., Millar, J., Kruth, H., & Rader, D. J. (2015) · Circulation Research · doi:10.1161/circresaha.116.305811 · Cited by 194
Flagged first, then by citations
Research works printed but not linked: 15
- Sparks, 2015, The enigmatic role of sortilin in lipoprotein metabolism, Curr. Opin. Lipidol., 26, 598, 10.1097/MOL.0000000000000244 · DOI
- Strong, 2014, Sortilin and lipoprotein metabolism: making sense out of complexity, Curr. Opin. Lipidol., 25, 350, 10.1097/MOL.0000000000000110 · DOI
- Kjolby, 2015, Sortilin, encoded by the cardiovascular risk gene SORT1, and its suggested functions in cardiovascular disease, Curr. Atheroscler. Rep., 17, 496, 10.1007/s11883-015-0496-7 · DOI
- Kjolby, 2010, Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export, Cell Metab., 12, 213, 10.1016/j.cmet.2010.08.006 · DOI · Paper page
- Ai, 2012, Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice, J. Clin. Investig., 122, 1677, 10.1172/JCI61248 · DOI
- Chamberlain, 2013, Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting, Biochem. Biophys. Res. Commun., 430, 66, 10.1016/j.bbrc.2012.11.022 · DOI
- Sparks, 2016, Insulin dependent apolipoprotein B degradation and phosphatidylinositide 3-kinase activation with microsomal translocation are restored in McArdle RH7777 cells following serum deprivation, Biochem. Biophys. Res. Commun., 469, 326, 10.1016/j.bbrc.2015.11.068 · DOI
- Sparks, 1986, The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins, Atherosclerosis, 61, 205, 10.1016/0021-9150(86)90139-5 · DOI
- Sparks, 2013, Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases, Biochem. Biophys. Res. Commun., 435, 616, 10.1016/j.bbrc.2013.05.029 · DOI
- Chirieac, 2006, PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice, Am. J. Physiol., 291, G382
- Halgren, 2004, Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening, J. Med. Chem., 47, 1750, 10.1021/jm030644s · DOI
- Quistgaard, 2014, Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin, Protein Sci., 23, 1291, 10.1002/pro.2512 · DOI
- Jacobson, 2004, A hierarchical approach to all-atom protein loop prediction, Proteins, 55, 351, 10.1002/prot.10613 · DOI
- Kummrow, 2002, Myristic acid increases dense lipoprotein secretion by inhibiting apoB degradation and triglyceride recruitment, J. Lipid Res., 43, 2155, 10.1194/jlr.M200249-JLR200 · DOI
- Schroder, 2014, The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin, Bioorg. Med. Chem. Lett., 24, 177, 10.1016/j.bmcl.2013.11.046 · DOI
Cited by
Sorted by citations
EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis
Ma, F., Longo, M., Meroni, M., Bhattacharya, D., Paolini, E., Mughal, S., Hussain, S., Anand, S. K., Gupta, N., Zhu, Y., et al. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.01.020 · Cited by 29
Metadata
- Authors
- Sparks, R. P., Guida, W. C., Sowden, M. P., Jenkins, J. L., Starr, M. L., Fratti, R. A., Sparks, C. E., & Sparks, J. D.
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 2016-09
- Volume
- 478
- Issue
- 2
- Pages
- 546-552
- ISSN
- 0006-291X
- PMC
- PMC5002383
- Cited by
- 17
- References
- 3
- Language
- en
- Funders
- National Institutes of Health (DK100163, GM101132)
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