Mood disorders: Regulation by metabotropic glutamate receptors

Pilc, Andrzej, Chaki, Shigeyuki, Nowak, Gabriel, Witkin, Jeffrey M.·2008·Biochemical Pharmacology

Cited by (166)

Items 101–166 of 166

  1. Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo
    Ji-Quan Wang, Zhaoda Zhang, Darshini Kuruppu, Anna‐Liisa Brownell · 2012 · Bioorganic & Medicinal Chemistry Letters
  2. Alterations in mGlu5 receptor expression and function in the striatum in a rat depression model
    Limin Mao, John Q. Wang · 2018 · Journal of Neurochemistry
  3. The role of DSCAM in the regulation of synaptic plasticity: possible involvement in neuropsychiatric disorders
    Katarzyna Stachowicz · 2018 · Acta Neurobiologiae Experimentalis
  4. Fluoroquinolone-induced suicidal ideation
    Elizabeth A. LaSalvia, Gretchen J. Domek, David F. Gitlin · 2009 · General Hospital Psychiatry
  5. Does conventional anti-bipolar and antidepressant drug therapy reduce NMDA-mediated neuronal excitation by downregulating astrocytic GluK2 function?
    Liang Peng, Baoman Li, Ting Du, Fanli Wang, Leif Hertz · 2011 · Pharmacology Biochemistry and Behavior
  6. Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats
    Marco Pignatelli, Barbara Vollmayr, S. Helene Richter, Silvia Middei, Francesco Matrisciano, Gemma Molinaro, Carla Nasca, Giuseppe Battaglia, Martine Ammassari‐Teule, Marco Feligioni et al. · 2012 · Neuropharmacology
  7. MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium–Pilocarpine Model of Epilepsy
    A. V. Dyomina, Anna A. Kovalenko, Maria V. Zakharova, Tatyana Y. Postnikova, Alexandra V. Griflyuk, Ilya V. Smolensky, Irina Antonova, Aleksey V. Zaitsev · 2022 · International Journal of Molecular Sciences
  8. Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors
    B.D. Harvey, Chester J. Siok, Tamás Kiss, Dmitri Volfson, S. Grimwood, Christopher L. Shaffer, Mihály Hajós · 2013 · Neuropharmacology
  9. mGlu2/3 receptor antagonists
    Shigeyuki Chaki · 2019 · Advances in pharmacology
  10. Ligation of metabotropic glutamate receptor 3 (Grm3) ameliorates lupus-like disease by reducing B cells
    Ning Ma, Xiaoling Liu, Xing Chen, Xiaoqian Wang, Yinxiang Wei, Gencheng Han, Guojiang Chen, Chunmei Hou, Beifen Shen, Yan Li et al. · 2015 · Clinical Immunology
  11. Are glutamate transporters neuroprotective or neurodegenerative during cerebral ischemia?
    Li‐Nan Zhang, Liang Hao, Yu-Song Guo, Haiyan Wang, Linlin Li, Li-Zhe Liu, Wenbin Li · 2019 · Journal of Molecular Medicine
  12. Role of interaction of mGlu2 and 5-HT2A receptors in antipsychotic effects
    Daisuke Ibi · 2022 · Pharmacology Biochemistry and Behavior
  13. Synthesis of α-CF3-containing triazolyl amino acids as potential neurotransmitters via click-reaction
    Daria V. Vorobyeva, Аlexander S. Peregudov, Gerd‐Volker Röschenthaler, Sergey N. Osipov · 2015 · Journal of Fluorine Chemistry
  14. Altered ADAR 2 equilibrium and 5HT2CR editing in the prefrontal cortex of ADAR 2 transgenic mice
    Minati Singh, M. M. Singh, E. Na, K. Agassandian, M. B. Zimmerman, A. K. Johnson · 2011 · Genes Brain & Behavior
  15. Noncoding RNAs in Depression
    Rixing Lin, Gustavo Turecki · 2017 · Advances in experimental medicine and biology
  16. Using Epigenetic Tools to Investigate Antidepressant Response
    Laura M. Fiori, Rixing Lin, Chelsey Ju, Raoul Belzeaux-R, Gustavo Turecki · 2018 · Progress in molecular biology and translational science
  17. Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2
    Fariba Khodagholi, Ali Maleki, Fereshteh Motamedi, Maryam Alsadat Mousavi, Shahrbanoo Rafiei, Mehdi Moslemi · 2020 · Cellular and Molecular Neurobiology
  18. Immune malfunction in the GPR39 zinc receptor of knockout mice: Its relationship to depressive disorder
    Katarzyna Młyniec, Ewa Trojan, Joanna Ślusarczyk, Katarzyna Głombik, Agnieszka Basta‐Kaim, Bogusława Budziszewska, Jakub Skrzeszewski, Agata Siwek, Birgitte Holst, Gabriel Nowak · 2015 · Journal of Neuroimmunology
  19. Deficiency of the palmitoyl acyltransferase ZDHHC7 impacts brain and behavior of mice in a sex-specific manner
    Christa Hohoff, Mingyue Zhang, Oliver Ambrée, Mykola Kravchenko, Jens Buschert, Nicole Kerkenberg, Nataliya Gorinski, Dalia Abdel Galil, Christiane Schettler, Kari Lavinia vom Werth et al. · 2019 · Brain Structure and Function
  20. Maternal high‐sugar diet results in NMDA receptors abnormalities and cognitive impairment in rat offspring
    Józef Mizera, Grzegorz Kazek, Ewa Niedzielska, Lucyna Pomierny-Chamioło · 2021 · The FASEB Journal
  21. Two grams of sarcosine in schizophrenia – is it too much? A potential role of glutamate- serotonin interaction
    Dominik Strzelecki, Justyna Szyburska, Jolanta Rabe‐Jabłońska · 2014 · Neuropsychiatric Disease and Treatment
  22. Spatial distribution of heavy metals of agricultural soils in Dongguan, China.
    Yunsheng Xia, Fangbai Li, Hongfu Wan, Jin Ma, Guoyi Yang, Tian-Bin Zhang, Wei Luo · 2004 · PubMed
  23. The [18F]FDG μPET Readout of a Brain Activation Model to Evaluate the Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator JNJ-42153605
    Tine Wyckhuys, Leonie Wyffels, Xavier Langlois, Mark E. Schmidt, Sigrid G. Stroobants, Steven G. Staelens · 2014 · Journal of Pharmacology and Experimental Therapeutics
  24. Tyrosine phosphorylation of glutamate receptors by non-receptor tyrosine kinases: roles in depression-like behavior
    Limin Mao, John Q. Wang · 2016 · Neurotransmitter
  25. Functional Coupling between Metabotropic Glutamate Receptors and G‐Proteins in Rat Cerebral Cortex Assessed by Guanosine‐5′‐O‐(3‐[35S]thio)triphosphate Binding Assay
    Yuji Odagaki, Masakazu Kinoshita, Ryoichi Toyoshima · 2011 · Basic & Clinical Pharmacology & Toxicology
  26. New Approaches to the Pharmacological Management of Major Depressive Disorder
    Jeffrey M. Witkin, Xia Li · 2009 · Advances in pharmacology
  27. Mutagenesis and Molecular Modeling of the Orthosteric Binding Site of the mGlu2 Receptor Determining Interactions of the Group II Receptor Antagonist 3H‐HYDIA
    Linda Lundström, Bernd Kuhn, Jennifer Beck, Edilio Borroni, Joseph G. Wettstein, Thomas J. Woltering, Silvia Gatti · 2009 · ChemMedChem
  28. MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation–Induced Depression-Like Behaviors in Mice
    Xiaolan Wang, Miao Cheng, Yanfang Su, Chun Zhang, Xianfang Meng · 2022 · The International Journal of Neuropsychopharmacology
  29. Assessing the Neuronal Serotonergic Target-based Antidepressant Stratagem: Impact of In Vivo Interaction Studies and Knockout Models
    Ramamoorthy Rajkumar, Radhakrishnan Mahesh · 2008 · Current Neuropharmacology
  30. Linkage of Non-receptor Tyrosine Kinase Fyn to mGlu5 Receptors in Striatal Neurons in a Depression Model
    Limin Mao, John Q. Wang · 2020 · Neuroscience
  31. Metabotropic glutamate type 5 receptor requires contactin‐associated protein 1 to control memory formation
    Xavier Morató, R. Luján, Nélio Gonçalves, M. Watanabe, X. Altafaj, A. L. Carvalho, V. Fernández-Dueñas, R. Cunha, F. Ciruela · 2018 · Human Molecular Genetics
  32. Metabotropic Glutamate Receptor 5 in the Medial Prefrontal Cortex as a Molecular Determinant of Pain and Ensuing Depression
    Geehoon Chung, Sang Jeong Kim, Sun Kwang Kim · 2018 · Frontiers in Molecular Neuroscience
  33. PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation
    Hiroki Yasuda, Hikaru Yamamoto, Kenji Hanamura, Mona Mehruba, Toshio Kawamata, Hiromi Morisaki, Masaaki Miyamoto, Shinji Takada, Tomoaki Shirao, Yoshitaka Ono et al. · 2020 · Communications Biology
  34. Glutamate Neurotransmission in Psychotic Disorders and Substance Abuse
    Berit Kerner · 2009 · The Open Psychiatry Journal
  35. Postpartum blues syndrome: Serum zinc and psychosocial factors
    Yessy Kurniati, Wardihan Sinrang, Saidah Syamsuddin · 2020 · Enfermería Clínica
  36. Neural signaling mechanisms in depression: bridging classical monoamine hypotheses, animal models, and emerging antidepressant strategies
    Mizuki Yamamoto, Haruka Hirakata, Koji Toda · 2026 · Frontiers in Cell and Developmental Biology
  37. Disruption of Glutamate Homeostasis in the Brain of Rat Offspring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet
    Józef Mizera, Bartosz Pomierny, Anna Sadakierska−Chudy, Beata Bystrowska, Lucyna Pomierny-Chamioło · 2022 · Nutrients
  38. [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
    Dominik Strzelecki, Paweł Kropiwnicki, Jolanta Rabe‐Jabłońska · 2013 · PubMed
  39. Exosomal miR-1202 mediates Brodmann Area 44 functional connectivity changes in medication-free patients with major depressive disorder: An fMRI study
    Shuguang Han, Qingtong Zheng, Zixuan Zheng, Jie Su, Xiaohua Liu, Changzhou Shi, Bo Li, Xuanxuan Zhang, Minghao Zhang, Qian Yu et al. · 2024 · Journal of Affective Disorders
  40. Blockade of mGluR1 and mGluR5 in the lateral habenula produces the opposite effects in the regulation of depressive-like behaviors in the hemiparkinsonian rats
    Kuncheng Liu, Yanping Hui, Yaxin Yang, Yuan Guo, Li Zhang · 2025 · Experimental Neurology
  41. Peanut oil odor enhances the immunomodulatory effect on immunosuppressed mice by regulating the cAMP signaling pathway via the brain–spleen axis
    Yijin Wang, Jianfu Wu, Ying Gong, Huiting Wang, Tao Wu, Rui Liu, Wenjie Sui, Min Zhang · 2024 · Food & Function
  42. Psychopharmacology and Mental Health Practice: An Important Alliance
    Kevin P. Kaut · 2011 · Journal of Mental Health Counseling
  43. Neuroimaging Approaches to the Understanding of Depression and the Identification of Novel Antidepressants
    Poornima Kumar, Catherine J. Harmer, Colin Trevor Dourish · 2012 · Elsevier eBooks
  44. Physical and crystallographic characterisation of the mGlu5 antagonist MTEP and its monohydrochloride
    Matthew J. McIldowie, Michael N. Gandy, Brian W. Skelton, Jonathan M. Brotchie, George A. Koutsantonis, Mark A. Spackman, Matthew Piggott · 2009 · Journal of Pharmaceutical Sciences
  45. Glutamate Function in Anxiety Disorders and OCD: Evidence from Clinical and Translational Studies
    Tália Cássia Boff, Silvio José Batista Soares, Millena Daher Medeiros Lima, Zuleide Maria Ignácio · 2022 · Springer eBooks
  46. Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors
    Limin Mao, Nirav Mathur, John Q. Wang · 2022 · IBRO Neuroscience Reports
  47. The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models
    Anton V. Malyshev, Vsevolod Vyacheslavovich Pavshintsev, Nikita A. Mitkin, Iuliia A. Sukhanova, Vasilina R. Gedzun, Alexander S. Zlobin, Igor I. Doronin, Gennady A. Babkin, Tomi K. Sawyer · 2024 · Frontiers in Behavioral Neuroscience
  48. Antidepressant-like Effects of the Gastrodia elata Bl Extract in Mice
    Soon-Sang Hong, Seung‐Hun Cho · 2013 · Journal of Oriental Neuropsychiatry
  49. A review on animal models of depression.
    Milind Parle, Sameer Dhingra · 2010 · Asian Journal of Biological Sciences
  50. Emerging role of microRNAs as novel targets of antidepressants
    Aarthi Manoharan, Abialbon Paul · 2021 · Asian Journal of Psychiatry
  51. mGlu2/3 Receptor Antagonists as Rapid-Acting Antidepressants
    Shigeyuki Chaki · 2021 · Contemporary clinical neuroscience
  52. Using Our Understanding of Stress-Related Effects on Glutamate Neurotransmission to Guide the Development of Novel Treatment Strategies
    Carly Kiselycznyk, Gerard Sanacora · 2014 · Springer eBooks
  53. Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors
    Jeffrey M. Witkin · 2010 · Birkhäuser Basel eBooks
  54. Chromatin Remodeling in Transgenic Mouse Brain: Implications for the Neurobiology of Depression: A Dissertation
    Yan ping Jiang · 2009 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  55. Glutamate Receptor 2 Positive Allosteric Modulator JNJ42153605
    Tine Wyckhuys, Leonie Wyffels, Xavier Langlois, Sigrid G. Stroobants · 2014
  56. Glutamate Signaling in Benign and Malignant Disorders: Current Status, Future Perspectives, and Therapeutic
    Implications S. Willard, Shahriar Koochekpour · 2013
  57. Thegenetics of major depression
    James B. Potash · 2012 · Cambridge University Press eBooks
  58. Glutamate as a Neural Stress Factor in Humans and Animals
    B.F. Kania, Katarzyna Ferdyn, Tomasz Wojnar, Grzegorz Lonc · 2019 · Journal of Behavioral and Brain Science
  59. Posttraumatic stress disorder, major depressive disorder, and noncoding RNAs
    Dušan Braný, Dana Dvorská, Laura E. Lockwood, Ján Strnádel, Nagy A. Youssef · 2022 · Elsevier eBooks
  60. Análise do transcriptoma da região do subiculum de modelo animal de epilepsia do lobo temporal mesial (ELTM) induzido por estimulação elétrica da via perfurante
    Beatriz B. Aoyama · 2020
  61. Prediction of microRNAs targeting oestrogen receptor beta: implications for emotional disorders
    Daniel Kalinowski, Magdalena Zielińska · 2025 · Neuroscience
  62. Développement des ligands pour l' étude des récepteurs GPCR, Tyrosine Kinase, basée sur l' utilisation de simple domaine d' anticorps de lamas
    Damien Névoltris · 2014
  63. BindingDB Entry 50032599: 1,2,3-triazolyl amino acids as AMPA receptor ligands.
    BindingDB · 2011 · UC San Diego
  64. BindingDB Entry 50040642: Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.
    BindingDB · 2013 · UC San Diego
  65. BindingDB Entry 50040732: Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): a positive allosteric modulator of the metabotropic glutamate 2 receptor.
    BindingDB · 2013 · UC San Diego
  66. BindingDB Entry 50032670: Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists.
    BindingDB · 2011 · UC San Diego