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Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is frequently over-expressed and functions as an oncogene in several tumor types

Windhorst, Sabine, Song, Kai, Gazdar, Adi F.·2017·Biochemical Pharmacology
DOI 10.1016/j.bcp.2017.03.023PMC PMC5555585
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Research works printed but not linked: 54

  1. Vanhaesebroeck, 2012, PI3K signalling: the path to discovery and understanding, Nat. Rev. Mol. Cell Biol., 13, 195, 10.1038/nrm3290 · DOI
  2. Thorpe, 2015, PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting, Nat. Rev. Cancer, 15, 7, 10.1038/nrc3860 · DOI
  3. Irvine, 1999, Inositol 1,3,4,5-tetrakisphosphate as a second messenger–a special role in neurones?, Chem. Phys. Lipids, 98, 49, 10.1016/S0009-3084(99)00017-1 · DOI
  4. Schurmans, 2011, Regulation of B cell survival, development and function by inositol 1,4,5-trisphosphate 3-kinase B (Itpkb), Adv. Enzyme Regul., 51, 66, 10.1016/j.advenzreg.2010.08.001 · DOI
  5. Shears, 2004, How versatile are inositol phosphate kinases?, Biochem. J., 377, 265, 10.1042/bj20031428 · DOI
  6. Irvine, 1986, The inositol tris/tetrakisphosphate pathway–demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues, Nature, 320, 631, 10.1038/320631a0 · DOI
  7. Stewart, 1986, Perturbation of the human T-cell antigen receptor-T3 complex leads to the production of inositol tetrakisphosphate: evidence for conversion from inositol trisphosphate, Proc. Natl. Acad. Sci. U. S. A., 83, 6098, 10.1073/pnas.83.16.6098 · DOI
  8. Takazawa, 1991, Erneux C molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme, Biochem. J., 278, 883, 10.1042/bj2780883 · DOI
  9. Takazawa, 1991, Molecular cloning and expression of a human brain inositol 1,4,5-trisphosphate 3-kinase, Biochem. Biophys. Res. Commun., 174, 529, 10.1016/0006-291X(91)91449-M · DOI
  10. Dewaste, 2000, Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C, Biochem. J., 352, 343, 10.1042/bj3520343 · DOI
  11. Dewaste, 2002, Cloning and expression of a full-length cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase B, Biochem. Biophys. Res. Commun., 291, 400, 10.1006/bbrc.2002.6456 · DOI
  12. Schell, 2001, Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminus, J. Biol. Chem., 276, 37537, 10.1074/jbc.M104101200 · DOI
  13. Brehm, 2004, Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B), Biochem. J., 382, 353, 10.1042/BJ20031751 · DOI
  14. Nalaskowski, 2011, Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope, J. Biol. Chem., 286, 4500, 10.1074/jbc.M110.173062 · DOI
  15. Nalaskowski, 2003, Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basalcellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm, J. Biol. Chem., 278, 19765, 10.1074/jbc.M211059200 · DOI
  16. Vanweyenberg, 1995, Tissue- and cell-specific expression of Ins(1,4,5)P3 3-kinase isoenzymes, Biochem. J., 306, 429, 10.1042/bj3060429 · DOI
  17. Jun, 1998, Enhanced hippocampal CA1 LTP but normal spatial learning in inositol 1,4,5-trisphosphate 3-kinase(A)-deficient mice, Learn Mem, 5, 317, 10.1101/lm.5.4.317 · DOI
  18. Kim, 2009, Inositol 1,4,5-trisphosphate 3-kinase a functions as a scaffold for synaptic Rac signaling, J. Neurosci., 29, 14039, 10.1523/JNEUROSCI.2483-09.2009 · DOI
  19. Siegemund, 2015, IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice, Blood, 125, 2786, 10.1182/blood-2014-06-583187 · DOI
  20. Scoumanne, 2016, Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice, Adv. Biol. Regul., 62, 1, 10.1016/j.jbior.2016.03.001 · DOI
  21. Onouchi, 2008, ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms, Nat. Genet., 40, 35, 10.1038/ng.2007.59 · DOI
  22. Alphonse, 2016, Inositol-Triphosphate 3-Kinase C mediates inflammasome activation and treatment response in Kawasaki disease, J. Immunol., 197, 3481, 10.4049/jimmunol.1600388 · DOI
  23. Ashour, 2015, The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin, Cytoskeleton (Hoboken), 72, 93, 10.1002/cm.21208 · DOI
  24. Pollard, 2016, Actin and actin-binding proteins, Cold Spring Harb. Perspect. Biol., 8, 10.1101/cshperspect.a018226 · DOI
  25. Spitaler, 2004, Protein kinase C and beyond, Nat. Immunol., 5, 785, 10.1038/ni1097 · DOI
  26. Mayr, 2005, Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase, J. Biol. Chem., 280, 13229, 10.1074/jbc.M500545200 · DOI
  27. González, 2004, Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase, Mol. Cell, 15, 689, 10.1016/j.molcel.2004.08.004 · DOI
  28. Hermosura, 2000, InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase, Nature, 408, 735, 10.1038/35047115 · DOI
  29. Windhorst, 2010, Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities, J. Biol. Chem., 285, 5541, 10.1074/jbc.M109.047050 · DOI
  30. Mailleux, 1991, Inositol 1,4,5-trisphosphate 3-kinase distribution in the rat brain. High levels in the hippocampal CA1 pyramidal and cerebellar Purkinje cells suggest its involvement in some memory processes, Brain Res., 539, 203, 10.1016/0006-8993(91)91622-8 · DOI
  31. Mailleux, 1991, Inositol 1,4,5-trisphosphate 3-kinase mRNA: high levels in the rat hippocampal CA1pyramidal and dentate gyrus granule cells and in cerebellar Purkinje cells, J. Neurochem., 56, 345, 10.1111/j.1471-4159.1991.tb02601.x · DOI
  32. Windhorst, 2012, Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients, Cell. Signal., 24, 750, 10.1016/j.cellsig.2011.11.010 · DOI
  33. Cooke, 2006, Plasticity in the human central nervous system, Brain, 129, 1659, 10.1093/brain/awl082 · DOI
  34. Rao, 2000, Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines, Hippocampus, 10, 527, 10.1002/1098-1063(2000)10:5<527::AID-HIPO3>3.0.CO;2-B · DOI
  35. Köster, 2016, Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines, Cell. Signal., 28, 83, 10.1016/j.cellsig.2015.10.016 · DOI
  36. Johnson, 2009, Neuronal IP3 3-kinase is an F-actin-bundling protein: role in dendritic targeting and regulation of spine morphology, Mol. Biol. Cell, 20, 5166, 10.1091/mbc.E09-01-0083 · DOI
  37. Windhorst, 2011, Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells, Int. J. Cancer, 129, 1300, 10.1002/ijc.25782 · DOI
  38. Wang, 2016, ITPKA gene body methylation regulates gene expression and serves as an early diagnostic marker inlung and other cancers, J Thorac Oncol, 11, 1469, 10.1016/j.jtho.2016.05.010 · DOI
  39. Maegawa, 2010, Widespread and tissue specific age-related DNA methylation changes in mice, Genome Res., 20, 332, 10.1101/gr.096826.109 · DOI · Paper page
  40. Noreen, 2014, Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle, J. Natl. Cancer Inst., 28, 106
  41. Coulson, 2000, A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker, Cancer Res., 60, 1840
  42. Majumder, 2006, REST in good times and bad: roles in tumor suppressor and oncogenic activities, Cell Cycle, 5, 1929, 10.4161/cc.5.17.2982 · DOI
  43. Pollard, 2016, Give it a REST!, eLife, 5, e12615, 10.7554/eLife.12615 · DOI
  44. Nechiporuk, 2016, The REST remodeling complex protects genomic integrity during embryonic neurogenesis, eLife, 5, e09584, 10.7554/eLife.09584 · DOI
  45. Westbrook, 2005, A genetic screen for candidate tumor suppressors identifies REST, Cell, 121, 837, 10.1016/j.cell.2005.03.033 · DOI
  46. Fukuoka, 2004, X Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer, Clin. Cancer Res., 10, 4314, 10.1158/1078-0432.CCR-03-0489 · DOI
  47. Chang, 2011, Expression Regulation of the Metastasis-Promoting Protein InsP3-Kinase-A in Tumor Cells, Mol. Cancer Res., 9, 497, 10.1158/1541-7786.MCR-10-0556 · DOI
  48. Benz, 1992, Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7cells transfected with HER2/neu, Breast Cancer Res. Treat., 24, 85, 10.1007/BF01961241 · DOI
  49. Pincini, 2013, Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells, Cell Cycle, 12, 2409, 10.4161/cc.25415 · DOI
  50. Woodring, 1996, Transformation of Rat-1 fibroblasts with the v-src oncogene induces inositol 1,4,5-trisphosphate 3-kinase expression, Biochem. J., 319, 73, 10.1042/bj3190073 · DOI
  51. Li, 2015, ITPKA expression is a novel prognostic factor in hepatocellular carcinoma, Diagn Pathol, 7, 136, 10.1186/s13000-015-0374-1 · DOI
  52. Schröder, 2015, The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells, Biochem. Pharmacol., 96, 143, 10.1016/j.bcp.2015.05.004 · DOI
  53. Bettegowda, 2014, Detection of circulating tumor DNA in early- and late-stage human malignancies, Sci. Transl. Med., 19, 224ra24, 10.1126/scitranslmed.3007094 · DOI · Paper page
  54. Schröder, 2013, Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A, Biochem. Biophys. Res. Commun., 20, 228, 10.1016/j.bbrc.2013.08.053 · DOI

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Metadata

Authors
Windhorst, S., Song, K., & Gazdar, A. F.
Venue
Biochemical Pharmacology
Publisher
Elsevier BV
Published
2017-08
Volume
137
Pages
1-9
ISSN
0006-2952
DOI
10.1016/j.bcp.2017.03.023
PMC
PMC5555585
Cited by
35
References
2
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • National Cancer Institute, USA (P50 CA70907)
  • Deutsche Krebshilfe (101383)

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