The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications
Open accessAbstract
Graphical abstract Figure. No Caption available. Abstract Hydrogen sulfide (H2S) is a ubiquitous small gaseous signaling molecule, playing an important role in many physiological processes and joining nitric oxide and carbon monoxide in the group of signaling agents termed gasotransmitters. Endogenous concentrations of H2S are generally low, making it difficult to discern precise biological functions. As such, probing the physiological roles of H2S is aided by exogenous delivery of the gas in cell and animal studies. This need for an exogenous source of H2S provides a unique challenge for chemists to develop chemical tools that facilitate the study of H2S under biological conditions. Compounds that degrade in response to a specific trigger to release H2S, termed H2S donors, include a wide variety of functional groups and delivery systems, some of which mimic the tightly controlled endogenous production in response to specific, biologically relevant conditions. This review examines a variety of H2S donor systems classified by their H2S‐releasing trigger as well as their H2S release profiles, byproducts, and potential therapeutic applications.
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Cites
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Cited by
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
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Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders
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Role of hydrogen sulfide in health and disease
Jin, Y., Yuan, H., Liu, Y., Zhu, Y., Wang, Y., Liang, X., Gao, W., Ren, Z., Ji, X., & Wu, D. (2024) · MedComm · doi:10.1002/mco2.661 · Cited by 54
Metadata
- Authors
- Powell, C. R., Dillon, K. M., & Matson, J. B.
- Venue
- Biochemical Pharmacology
- Publisher
- Elsevier BV
- Published
- 2018-03
- Volume
- 149
- Pages
- 110-123
- ISSN
- 0006-2952 (ISSN-L)
- OpenAlex
- W2768590554
- Cited by
- 599
- References
- 97
- FWCI
- 16.83
- Type
- journal article
- Language
- en
- Open access
- bronze
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