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The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

Open access
Powell, Chadwick R., Dillon, Kearsley M., Matson, John B.·2018·Biochemical Pharmacology

Abstract

Graphical abstract Figure. No Caption available. Abstract Hydrogen sulfide (H2S) is a ubiquitous small gaseous signaling molecule, playing an important role in many physiological processes and joining nitric oxide and carbon monoxide in the group of signaling agents termed gasotransmitters. Endogenous concentrations of H2S are generally low, making it difficult to discern precise biological functions. As such, probing the physiological roles of H2S is aided by exogenous delivery of the gas in cell and animal studies. This need for an exogenous source of H2S provides a unique challenge for chemists to develop chemical tools that facilitate the study of H2S under biological conditions. Compounds that degrade in response to a specific trigger to release H2S, termed H2S donors, include a wide variety of functional groups and delivery systems, some of which mimic the tightly controlled endogenous production in response to specific, biologically relevant conditions. This review examines a variety of H2S donor systems classified by their H2S‐releasing trigger as well as their H2S release profiles, byproducts, and potential therapeutic applications.

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Metadata

Authors
Powell, C. R., Dillon, K. M., & Matson, J. B.
Venue
Biochemical Pharmacology
Publisher
Elsevier BV
Published
2018-03
Volume
149
Pages
110-123
ISSN
0006-2952 (ISSN-L)
OpenAlex
W2768590554
Cited by
599
References
97
FWCI
16.83
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications. https://app.cochat.ai/papers/10.1016/j.bcp.2017.11.014
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Powell, C. R., Dillon, K. M., & Matson, J. B. (2018). A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications. Biochemical Pharmacology. https://doi.org/10.1016/j.bcp.2017.11.014

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