Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine
Brown, Bryan N., Ratner, Buddy D., Goodman, Stuart B., Amar, Salomon, Badylak, Stephen F.·2012·Biomaterials
Cited by (927)
Items 801–900 of 927
- Effects of Polymeric Materials on Activation of THP-1 Cell-derived Macrophages during Differentiation Induced by PMAShota Toda, Yoshihide Hashimoto, Naoko NAKAMURA, Masahiro Yamada, Ryusuke Nakaoka, Wataru Nomura, Masaya Yamamoto, Tsuyoshi KIMURA, Akio Kishida · 2024 · Advanced Biomedical Engineering
- Constructive tissue remodeling by extracellular matrix bioscaffolds within the aging skeletal muscle microenvironmentBrian M. Sicari · 2013 · D-Scholarship@Pitt (University of Pittsburgh)
- Cellular response of blood-borne immune cells to PEEU fiber meshesJanita A. Maring, Matthias Becker, Wing Tai Tung, Christof Stamm, Nan Ma, Andreas Lendlein · 2021 · Clinical Hemorheology and Microcirculation
- Biomaterials Selection – Cellular Interactions During Regenerative and Remodeling PhasesItzhak Binderman, Michal Halperin‐Sternfeld, Erez Netanely, Snježana Pohl, Robert A. Horowitz, Zvi Artzi · 2020
- Mesenchymal Stem Cell-Conditioned Media-Loaded Microparticles Enhance Acute Patency in Silk-Based Vascular Grafts2024
- Apoptosis as a strategy for enhancing decellularization and remodeling of tissue-engineered heart valvesPascal Breitenstein, Marcy Martin, Valery Lilian Visser, Sarah E. Motta, Maximilian Y. Emmert, Melanie Generali, Simon Philipp Hoerstrup · 2025 · Biomaterials
- Mechano-immunomodulatory biomaterials: From immune mechanosensing to translational designRuiyue Hang, Xiaohong Yao, Long Bai, Yin Xiao, Ruiqiang Hang · 2026 · Bioactive Materials
- An injectable hydrogel of porcine cholecyst extracellular matrix for accelerated wound healing2024
- Tailoring 3D Biomaterials for Spinal Cord Injury Repair2021
- Comparative Effects of Cellulose- and Gelatin-Based Hemostatic Biomaterials on the Early Stage of Wound Healing—An In Vivo StudyHelena Hae In Ströthoff, Polina Shabes, Katharina Henrika Beckamp, Markus Udo Wagenhäuser, Wiebke Ibing, Julian‐Dario Rembe, Hubert Schelzig, Waseem Garabet · 2026 · Journal of Functional Biomaterials
- Role of DAMPS on the modulation of macrophage response after classical biomaterial (Ti) implantation and its impact on the subsequent repair and osseointegration processesCláudia Cristina Biguetti · 2018
- From Microenvironment to Nanoenvironment: Ultrastructure and Function of Extracellular MatrixMandana Veiseh, Arya Nikjoo, Eva Ann Turley, Mina J. Bissell · 2014 · CRC Press eBooks
- Spontaneous dynamic modulation of ionic/immune microenvironment on polyetheretherketone for sequential anti-infection and osseointegration2025
- Orchestrating the immuno-chondrogenic microenvironment via a bio-inorganic hybrid microsphere system for tendon-to-bone healing2026
- Safety of terminally gamma-ray-sterilized screws coated with fibroblast growth factor 2-calcium phosphate composite layers in non-human primatesYukei Matsumoto, Hirotaka Mutsuzaki, Katsuya Nagashima · 2022 · Journal of Artificial Organs
- Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide RegenerationIan D. Dryg, Le Zhen, Rebecca Darrow, Savannah Lawton, Lars Crawford, Robert Robinson, Steve I. Perlmutter, James D. Bryers, Buddy D. Ratner · 2026 · Advanced Healthcare Materials
- Predicting the Future of Orthopaedic Trauma ImplantologyVaibhav B. Bagaria, Amit Sharma, Omkar S. Sadigale · 2023 · Springer eBooks
- Immunomodulatory Nanofibrous Membrane Based on Collagen/Curdlan Acetate for Accelerated Wound Repair2024
- Acellular Lung Scaffolds in Lung BioengineeringDarcy Elizabeth Wagner, Franziska E. Uhl, Daniel J. Weiss · 2015 · Stem cell biology and regenerative medicine
- Engineering the cartilage niche: Mimicking the microenvironment for functional outcomesPardis Yousefi Talouki, Reyhaneh Tamimi, Moein Mahmoodi · 2026 · Tissue and Cell
- Cardiac regenerationRaghav Alampalli Murthy, Aditya Sengupta · 2019 · Elsevier eBooks
- Mesenchymal stromal cells and biological scaffolds for neural tissue regenerationZuzana Kočí · 2018 · Digital Repository (National Repository of Grey Literature)
- Fermented Plant Extract-Loaded Collagen Scaffolds: Bioactive Hydrogels for Enhanced Wound Repair and Immune ModulationLesly Katleya Usme-Duque, Miguel Á. Medina-Morales, María I. León‐Campos, Marisol Cruz Requena, Leopoldo J. Ríos-González, Rebeca Betancourt‐Galindo, Jesús A. Claudio‐Rizo · 2026 · Gels
- Molecular signalling mechanisms of host–materials interactionsJ.F. da Silva Domingues, Theo G. van Kooten · 2016 · Elsevier eBooks
- 3D ‐Printed Precision Porous Scaffolds Promote Healing In VivoGuoyao Chen, Sharon A. Creason, Ningjing Chen, Adia Kirkham, Le Zhen, Shijie Zhang, Kai Ming Wu, Buddy D. Ratner · 2025 · Journal of Biomedical Materials Research Part A
- Targeting the Immune Network in Endometriosis: A Comprehensive Review of Pathogenesis, Immunomodulation, and Emerging TherapiesYukun Mo, M Li, Wei Ye, Zhuozhen Jiang, Xian-Hua Lin, Luo Kewang · 2026 · Pharmaceuticals
- Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative InterfacesRoberto S. [UNESP] Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil Martin O’brien-simpson, Vladimir A. Baulin, Peter Kingshott, Roy B. Judge, Alastair James Sloan, Elena Pavlovna Ivanova · 2026 · Journal of Periodontal Research
- Investigating biomaterial-based biophysical cues for modulating macrophage polarization towards bone regeneration applicationsRukmani Sridharan · 2019
- Modulación de la respuesta inflamatoria mediante membranas de colágeno-oligouretano-síliceEstudiante Maestría en Ciencias Aplicadas, DCI, Universidad de Guanajuato, Pedro U. Muñoz‐González, Birzabith Mendoza‐Novelo, Docente Investigador, DCI, Universidad de Guanajuato, J. Delgado, Docente Investigador, DCI, Universidad de Guanajuato, Lucio Castellano, Docente Investigador, DCI, Universidad de Guanajuato · 2018 · Memorias del Congreso Nacional de Ingeniería Biomédica
- Predicting the Future in Orthopedic ImplantologyVaibhav B. Bagaria, Amit Sharma, Omkar S. Sadigale · 2021 · Springer eBooks
- Clinical Translation Challenges and Future Paradigms of Advanced ECMO Coatings: Scalability, Hemocompatibility, and Regulatory Barriers2026
- Nanoparticle-Enabled Biomaterials for Controlled Drug Delivery in Implantable and Wearable DevicesZahrah Asiri, Abeer Mobarki, Sahar S. Alghamdi, Abdulaziz A. Almoutairi, Fatimah Alsalman, Rawan Anwar Fitaihi, Njoud Altuwaijri, Arwa Alsubait, Yahya Fahad Jamous · 2026 · International Journal of Molecular Sciences
- Editorial: Calcium Phosphate Ceramics: The Living Bridge Between Biology and Biomaterials2025
- Extracellular Matrix-Enhanced Biomimetic Scaffolds for Tissue-Specific Orthopaedic Tissue EngineeringBenjamin B. Rothrauff · 2016 · D-Scholarship@Pitt (University of Pittsburgh)
- Individual and combinatorial effects of stiffness and electrical conductivity on host-immune responses to conductive hydrogelsJae Young Lee, Sanghun Lee, Junggeon Park · 2023 · Research Square
- Gene expression of Bcl2a1 และ Cxcl9 in soft tissue covering bone grafting materialsBorwonluk Taveedach, Jaijam Suwanwela · 2018
- Extracellular matrix bioscaffolds for treatment of volumetric muscle lossJenna L. Dziki · 2017 · D-Scholarship@Pitt (University of Pittsburgh)
- Orchestrating membranous biomaterials preservation: multi-pathway immunomodulation of macrophage fusion and membrane stability via BAPTA-loaded mesoporous silica nanoparticlesGuanqi Liu, Xiaoyan Chen, Jiahui Lin, Yuhan Hou, Runheng Liu · 2026 · Materials & Design
- Development of tissue based biomaterials for articular cartilage injuriesColten Snider · 2020
- Biomaterials for Tissue Engineered Cartilage Product for Orthopedic (Osteoarthritis) ReconstructionSuraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar · 2025 · Springer eBooks
- Tissue Engineering for Massive Bone Defects: The Volumetric Scaling Problem and Strategies to Solve ItSedeek M. Mosaid, Yousif Jihad, Mostafa Jihad · 2026 · Bioengineering
- Off-the-Shelf Implant to Bridge a Urethral Defect: Multicenter 8-Year Journey From Bench to Bed2024
- Biomaterial-based microenvironment remodeling for functional regeneration of scarred uterus tissueWanting Yang, Ying Xu, Wensheng Xie · 2026 · Journal of Materials Chemistry B
- In Vivo Tissue-Engineered Vascular GraftsBeat H. Walpoth, Sarra de Valence, Jean‐Christophe Tille, Damiano Mugnai, Tornike Sologashvili, Wojciech Mrówczyński, Mustafa Çıkırıkçıoğlu, Erman Pektok, Suzanne M. Osorio Lujan, Francesco Innocente et al. · 2020 · Springer eBooks
- Interpretable AI-driven materiomics to decode microenvironmental cues for stem cell immunomodulationChenxi Pan, Yi He, Yingying Duan, Kaiwen Chen, Xiangying Wang, Xiangying Wang, Yonggang Zhang, Chuanfeng An, Huanan Wang · 2026 · Bioactive Materials
- Nanofiber, Microfiber, or Hybrid: Which Architecture Excels in Soft Tissue Reinforcement and Constructive Regeneration?S. M. Shatil Shahriar, Navatha Shree Sharma, Syed Muntazir Andrabi, Bidya Mondal, Zishuo Yan, Simran K. Rainu, Abigail F. Hellman, Milton E. Busquets, Jaiden L. Rensch, Riley G. Perez et al. · 2026 · ACS Applied Materials & Interfaces
- Intrinsic osteoinduction and osteogenesis of biomimetic calcium phosphate scaffolds with different nano-, micro- and macroporosities : ectopic and orthotopic implantation in a canine model2018
- NovaBone Bioactive Glass for Oral Bone Regeneration: Mechanisms, Innovations, and Clinical OutcomesM. Ashfaque Khan, Asad M Mujawar, Akriti Agrawal, Debi P Acharya, Deepti Krishnan Kutty, Laxman Roy Chittaluri, Kafeel Ahmed Md, Rubeena Naaz · 2026 · Cureus
- Biomaterials for Prolapse RepairSophya Breedlove, Amanda M. Artsen, Katrina Knight · 2026 · Springer eBooks
- A DLP-Printed 3D Bioceramplug Fabricated Using a Photocurable Negative Thermo-Responsive Bioceramic Slurry for Cranial Burr-Hole RepairYU-FENG SU, Chih-Yun Lee, Yen-Han Lai, Shih‐Hao Huang, Sung-Yen Lin, Chung‐Hwan Chen, Chih‐Kuang Wang · 2026 · ACS Biomaterials Science & Engineering
- Polymer-Based Coatings for Cardiovascular and Endovascular Devices: Linking Surface Chemistry, Drug Release Kinetics, and Thrombo-Inflammatory Performance: A ReviewRaşit Dinç, Nurittin Ardıç · 2026 · Polymers
- Regenerative Rehabilitation: Synergizing Regenerative Medicine Therapies with Rehabilitation for Improved Muscle Regeneration in Muscle PathologiesKristen M. Stearns-Reider, Fabrisia Ambrosio · 2015 · Stem cell biology and regenerative medicine
- Preclinical Analysis of Sex-Specific Differences in the Angiogenic and Inflammatory Tissue Response to Surgical SuturesSelina Wrublewsky, Jan Weigl, Caroline Bickelmann, Matthias W. Laschke · 2026 · Journal of Functional Biomaterials
- Mechanisms of Biomaterial-Mediated Cardiac and Esophageal RepairRicardo Londoño · 2015 · D-Scholarship@Pitt (University of Pittsburgh)
- The Pivotal Role Of Fibrocytes On Foreign Body ReactionsDavid W. Baker · 2016 · UTA ResearchCommons (University of Texas Arlington)
- Bioactive glass scaffolds: biological interactions and applications in tissue engineeringMaximilian Nikolas Moll, Fabian Westhauser, Linn Anna Fiehn · 2026 · Elsevier eBooks
- Is less inflammation always better? Rethinking remodeling in PRP-modified tissue-engineered vascular grafts - Correspondence2025
- Characterization of Physicochemical, Biocompatible Properties and Investigation on Repair Mechanism of Three Typical ECM Meshes in Vitro and in VivoWenting Ruan, Guowei Wang, Qiujin Qu, Xiaoxiao Gai, Changbin Wang, Jia Liu, Fuyu Zhu, Zhonghua Qu, Chenghu Liu · 2025 · Research Square
- Морфологическая оценка тканевой реакции на полипропиленовый сетчатый имплантат и шовные материалы в экспериментеА.Г. Рамков, Д.А. Клюйко, Т.А. Летковская · 2026 · Хирургия Восточная Европа
- Upregulated lncARAT in Schwann Cells Promotes Axonal Regeneration through Recruiting Macrophages and Inducing Macrophages M2 Polarization2021
- Fish skin grafts for human wound healing: mechanistic evidence, clinical performance, application strategies and translational challenges – a reviewG S R Kedari, Tejasvi Rajesh, Meivelu Moovendhan · 2026 · International Immunopharmacology
- Strontium-Loaded Nanotubes of Ti–24Nb–4Zr–8Sn Alloys for Biomedical ImplantationFei Liu, Xinyu Wang, Shujun Li, Yiheng Liao, Xinxin Zhan, Anqi Tao, Zheng Fu, Huazhi Li, Yucheng Su, Jiuhui Jiang et al. · 2021 · Journal of Biomedical Nanotechnology
- Multi-scale assessment of scaffold-guided regeneration in human extraction sockets using an ultra-porous TiO₂ biomaterialReem Jamous, Ingvild Nysæther, Håvard Jostein Haugen, Ståle Petter Lyngstadaas, Malin Vestin Fredriksson, Jan Eirik Ellingsen, Thaqif El Khassawna · 2026 · Acta Biomaterialia
- Upregulated lncARAT in Schwann cells promotes axonal regeneration through recruiting macrophages and inducing macrophages M2 polarization2021
- Macrophage microRNA-146a is a central regulator of the foreign body response to biomaterial implants2024
- A facile tannic acid/gentamicin-loaded biodegradable silk fibroin lifting thread with robust mechanical and antibacterial propertiesYuejie Dou, Shihao Song, Xuchen Wang, Fanlei Yang, Yan Du, Xiaoyu Zhang, Zibo Chen, Jia Yu, Gang Li · 2026 · Bioresource Technology
- EVALUATION OF THE WOUND HEALING PROCESS BY IMMUNOHISTOCHEMISTRY AND PICROSIRIUS RED STAINING2017
- Integrating Tissue Microenvironment with Scaffold Design to Promote Immune-Mediated RegenerationKaitlyn Sadtler, Franck Housseau, Drew M. Pardoll, Jennifer H. Elisseeff · 2015 · Springer eBooks
- Improved Corrosion Fatigue and Immunomodulatory Osteogenesis of Hydrothermally Grown TiO 2 Nanorods Coated SMATed-TitaniumHongwei Yang, Meng Yu, Rong Wang, Bo Li, Xin Zhao, Yulin Hao, Zheng Guo, Yong Han · 2020 · SSRN Electronic Journal
- Adipose-derived stem cells for wound healing and fibrosisYasamin Samadi, Francesco Maria Egro, Ricardo Luis Rodriguez, Asim Ejaz · 2021 · Elsevier eBooks
- Heart valve tissue engineering: current preclinical and clinical approaches2020
- Immune-epigenetic convergence in biomaterial-guided tissue regenerationWantong Wen, Zhen Wang, Margaret Armintrout, Annabella Duong, Le Yu · 2026 · Materials Today Bio
- In Vivo Tissue-Engineered Vascular GraftsBeat H. Walpoth, Sarra de Valence, Jean‐Christophe Tille, Damiano Mugnai, Tornike Sologashvili, Wojciech Mrówczyński, Mustafa Çıkırıkçıoğlu, Erman Pektok, Suzanne M. Osorio Lujan, Francesco Innocente et al. · 2020 · Springer eBooks
- Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages2022
- Rapidly Photocurable Corneal Interlamellar Adhesive for Deep Anterior Lamellar KeratoplastyZhenyu Luo, Yue Yin, Lingxuan Zhu, Mengna Guo, Bin Liu, Ke Ma, Bo Jiang · 2024 · ACS Applied Engineering Materials
- Substrate Curvature Influences Cytoskeletal Rearrangement and Modulates Macrophage Phenotype2024
- A novel role for TRPV1 in macrophage giant cell formationKarunakaran Reddy Sankaran, Mohammad Imran Khan, Shaik O. Rahaman · 2026 · American Journal of Physiology-Cell Physiology
- Reply to: Observation on the article “Long‐term follow‐up comparison of two different bilayer dermal substitutes in tissue regeneration: Clinical outcomes and histological findings”Barbara De Angelis, Pietro Gentile · 2020 · International Wound Journal
- Regulation of HepG2 Fat Metabolism by IL1β and IL1 Receptor AntagonistSusmita Chandra · 2017 · Cancer Research Journal
- Functionalizing Titanium Alloys for Bioelectronics: Anodization, Conducting Polymers and Biosensor IntegrationIldiko Peter, Alex-Barna Kacsó · 2026 · IntechOpen eBooks
- M13 phage surface induced modulation of macrophage polarization promotes anti-inflammatory responsesZohreh Safari, Majid Sadeghizadeh, Golareh Asgaritarghi, Hassan Bardania, Dina Sadeghizadeh, Sara Soudi · 2020
- Electroactive Poly(Vinylidene Fluoride-Trifluoroethylene)-Zinc Oxide Nanorod Films for Macrophage Polarization RegulationSiyuan Fan, Chengwei Wu, Qin Luo, Xin Xin, Weiming Lin, Yaoting He, Xingyan Yu, Xuzhao He, Wenjian Weng, Kui Cheng · 2026 · ACS Applied Materials & Interfaces
- Immunomodulatory Nanofibrous Membrane Based on Collagen/Curdlan Acetate for Accelerated Wound Repair2024
- Biologic Scaffolds Composed of Extracellular Matrix as a Natural Material for Wound HealingElizabeth W. Kollar, Christopher L. Dearth, Stephen F. Badylak · 2014
- Macrophage-to-Myofibroblast Transition (MMT) – an adverse response to polypropylene mesh implanted for pelvic organ prolapse repair surgery in a non-human primate modelMarrisa A. Therriault, K. Knight, Srividya Kottapalli, Temitope Obisesan, Malini Harinath, Bryan N. Brown, Pamela A. Moalli · 2025 · bioRxiv
- Extracellular Matrix Remodeling and Dermal Microenvironment Modulation in Regenerative Facial Aesthetics: A Critical Review of Collagen Biostimulators, Fibroblast Senescence, and Cutaneous AgingPaola Tatiana Espinosa Cruel, Camila Pascoal Correia dos dos Santos, Daniela Vieira Buchaim, Silvia Yaoska Caldera González, Geraldo Marco Rosa, Camila Aparecida RIBEIRO, Carlos Henrique Bertoni Reis, Rogério Leone Buchaim · 2026 · Cosmetics
- Additional file 6 of Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages2022
- Huxin Formula Inhibits Oxidized low-Density Lipoprotein-Induced Foam Cell Formation in THP-1 Macrophages via the LOX-1/NF-κB Pathway2024
- Orchestrating Osteoimmunity: Poly- l -lactic Acid Electrospun Membranes Direct Macrophage Fate to Activate the IL10-JAK2-STAT3 Cascade for Osteogenic DifferentiationDaiyuan Tang, Yunrong Xu, Zhenping Xiao, Jingyu Li, Chenxun Sun, Xinfu Zhang, Fei He, Chen Zhu, Bing Han · 2026 · Biomacromolecules
- In Vivo Bioreactor: New Type of Implantable Medical DevicesQiang Tan · 2013 · Springer eBooks
- The development of a tissue engineered vascular graft using a poly(glycerol sebacate) methacrylate scaffoldSamand Pashneh‐Tala · 2017 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
- Eighth Symposium on Biologic Scaffolds for Regenerative MedicineChristopher L. Dearth · 2014 · Regenerative Medicine
- Xenogeneic Skin Transplantation Promotes Angiogenesis and Tissue Regeneration Through Vitamin D-Activated Trem2+ Macrophages2021
- Développement de films minces de polyuréthanes sur du Cobalt Chrome : amélioration de l’hémocompatibilité d’un métal de référence utilisé dans la fabrication d’endoprothèses vasculairesAudrey Gossart · 2019 · theses.fr (ABES)
- The influence of chemically modified Gellan Gum on macrophage polarization, fibroblast differentiation, and collagen orientationZhuqing Li · 2021
- Unravelling the Mechanisms behind Periosteal Regeneration and its Application in Bone Tissue EngineeringJeremy Baldwin · 2017 · Queensland University of Technology
- Harnessing Apoptosis to Guide in Situ Remodeling of Tissue Engineered Heart ValvesPascal Breitenstein, Marcy Martin, Valery Lilian Visser, Sarah E. Motta, Maximilian Y. Emmert, Simon Philipp Hoerstrup · 2024 · SSRN Electronic Journal
- Histomorphometric evaluation of bone healing capacity of epigallocatechin-3-gallate-loaded β-TCP bone substitute in rabbit calvarial defects2018
- Human macrophage adhesion is significantly higher on SIBS based glaucoma microshunts than on common intraocular lens materials in vitroDirk Bauer, Maren Kasper, Schell Melanie, Carsten Heinz, Arnd Heiligenhaus · 2026 · Scientific Reports
- Small Molecules in Regenerative Medicine: Advancements, Applications, and ChallengesParthiban Chokkalingam, Manoranjan Bera, Sasmita Das, Mariko Saito, Bhaskar C. Das · 2025 · Springer eBooks