Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice

Wang, Hu; Zhu, Yang-Yang; Wang, Li; Teng, Tian; Zhou, Meng; Wang, Shu-Guang; Tian, Yi-Zhu; Du, Lei; Yin, Xiao-Xing; Sun, Ying

doi:10.1016/j.biopha.2017.10.022

Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease globally. The progression of NAFLD is complex and associated with inflammation, oxidative stress, autophagy, endoplasmic reticulum stress, and insulin resistance. Mangiferin, a natural C-glucosyl xanthone, has been reporte…