High rate heptanoate production from propionate and ethanol using chain elongation
Open accessAbstract
Heptanoate (or enanthate), a saturated mono-carboxylate with seven carbon atoms, is a commercially produced biochemical building block with versatile applications. Currently, heptanoate is mainly derived from the oxidation of heptaldehyde, which can be obtained after pyrolysis of castor oil. The objective of this investigation was to achieve efficient high rate heptanoate production using a mixed culture chain elongation process based on propionate and ethanol. An efficient high rate heptanoate production using chain elongation could offer an alternative for heptanoate production from castor oil. The investigation was performed in an upflow anaerobic filter with a hydraulic retention time of 17 h. A heptanoate production rate of 4.5 g l(-1) d(-1) was achieved with a heptanoate concentration of 3.2 g l(-1). These results show sufficient potential to consider this approach as an alternative for heptanoate production from castor oil. Future research should make heptanoate production from propionate and ethanol more cost-effective.
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References 18 · Cited by 96
- Authors
- Grootscholten, T. I. M., Steinbusch, K. J. J., Hamelers, H. V. M., & Buisman, C. J. N.
- Affiliations
- Wageningen University & Research (NL)
- Corresponding author
- Grootscholten, T.I.M.
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2013-05
- Volume
- 136
- Pages
- 715-718
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2116641995
- Cited by
- 96
- References
- 18
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 5 · 2023: 9 · 2022: 8 · 2021: 9 · 2020: 12 · 2019: 10 · 2018: 8 · 2017: 6 · 2016: 9 · 2015: 2 · 2014: 1 · 2013: 3
- FWCI
- 8.73
- Type
- journal article
- Language
- en
- Open access
- green
- research.wur.nl
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Socio-Environmental Systems Modeling (acceptedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Building and Construction › Anaerobic Digestion and Biogas Production
- Physical Sciences › Environmental Science › Environmental Engineering › Microbial Fuel Cells and Bioremediation
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Keywords
- heptanoate, chain extension, propionate, ethanol, mixed culture, upflow anaerobic filter, castor oil
- MeSH terms
- Ethanol, Biotechnology, Caproates, Fatty Acids, Heptanoates, Propionates
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