Progress of flexible strain sensors for physiological signal monitoring
Abstract
Flexible strain sensors, as a key component of the cutting-edge wearable and implantable electronics, have facilitated applications pertaining to human health monitoring and diagnosis. To fulfill the increasing requirements of sensing performance and broadening the application scope, novel materials and device design strategies have been continuously developed over the past decade. Herein, the recent progresses of flexible strain sensors developed for monitoring the physiological signals are selectively reviewed, from the perspective of the possible correlation between the device microstructure and their corresponding applications. Firstly, representative strain sensors developed based on four fundamental working mechanisms: piezoresistance, capacitance, piezoelectricity and triboelectricity are respectively introduced, subclassified by the type of active material or the similarity in microstructure. Next, a number of biomedical applications of flexible strain sensors are highlighted, including the detections of different types of physiological signals using specific microstructured strain sensors. Lastly, the role of the transduction mechanism and the device microstructure in the sensing characteristic are comprehensively discussed, and prospective forms of flexible strain sensors to meet the existing and future challenges in wearable/implantable electronics are summarized.
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Mechanical sensors detect deformation and contact force using piezoresistive/piezoelectric effects or capacitance changes, and are used for limb flexion analysis, posture adjustment and rehabilitation training.
“Detect deformation and contact force using | piezoresistive/piezoelectric effects or capacitance | changes.”
From Recent advances in intelligent wearable systems: from multiscale biomechanical features towards human motion intent prediction (2026) · cites this paper as [205]
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References 152 · Cited by 250
- Authors
- Shen, Z., Liu, F., Huang, S., Wang, H., Yang, C., Hang, T., Tao, J., Xia, W., & Xie, X.
- Affiliations
- Sun Yat-sen University (CN)
- Corresponding author
- Liu, Fanmao
- Xia, Wenhao
- Xie, Xi
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2022-09
- Volume
- 211
- Pages
- 114298
- ISSN
- 0956-5663 (ISSN-L)
- OpenAlex
- W4224316131
- Cited by
- 250
- References
- 152
- Citations by year
- 2026: 49 · 2025: 91 · 2024: 64 · 2023: 37 · 2022: 9
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (31900954, 32171335, 32171399, 81673179)
- Medical Science and Technology Foundation of Guangdong Province
- National Key Research and Development Program of China (2021YFA0911100, 2021YFF1200700)
- Science and Technology Planning Project of Guangdong Province (2017A020215085)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Nanomaterials and Printing Technologies
- Keywords
- flexible strain sensors, physiological monitoring, wearable electronics, implantable electronics, piezoresistivity, capacitive sensing, piezoelectric properties, triboelectricity, transduction mechanisms, human health monitoring
- MeSH terms
- Wearable Electronic Devices, Electronics, Humans, Monitoring, Physiologic, Biosensing Techniques
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