The DOI matches its Crossref record.
Bilaterality of ovarian endometriomas does not affect the outcome of in vitro fertilization/intracytoplasmic sperm injection in infertile women after laparoscopic cystectomy
Open accessAbstract
BACKGROUND: To assess whether the unilateral or bilateral lesions can affect ovarian reserve and pregnancy outcome in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in infertility patients underwent laparoscopic cystectomy. METHODS: A total of 148 IVF/ICSI cycle in patients who had undergone laparoscopic cystectomy for unilateral or bilateral endometriomas were reviewed retrospectively. There were 103 cycles where laparoscopic cystectomy had been carried out for unilateral endometriomas and 45 cycles after bilateral-side surgery. Primary outcome measures were ovarian reserve and ovarian response. Secondary outcome measures were the implantation rate, clinical pregnancy rate, and live birth rate. RESULTS: The number of dominant follicle on the day of human chorionic gonadotropin (hCG) administration (5.2 ± 3.1 vs. 4.2 ± 2.7; p = 0.048), and oocytes retrieved (10.0 ± 6.9 vs. 7.6 ± 6.6; p = 0.047) were significantly lower in the bilateral-side group compare with the unilateral-side group. However, the mean number of antral follicle count, metaphase II oocytes, the doses of gonadotropin used, fertilization rate, the rate of good quality embryos transferred, implantation rate and clinical pregnancy, live-birth rate and miscarriage rate were similar between the two groups. CONCLUSION: There were no associations among the bilaterality of ovarian endometriomas, ovarian reserve and pregnancy outcomes in IVF/ICSI cycles. However, bilateral ovarian endometriomas after laparoscopic cystectomy may impair ovarian response as compared to unilateral ovarian endometrioma.
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Research works printed but not linked: 17
- Moen, 1991, Is a long period without childbirth a risk factor for developing endometriosis?, Hum Reprod, 6, 1404, 10.1093/oxfordjournals.humrep.a137278 · DOI
- Vercellini, 2003, Coagulation or excision of ovarian endometriomas?, Am J Obstet Gynecol, 188, 606, 10.1067/mob.2003.7 · DOI
- Vercellini, 1998, Is cystic ovarian endometriosis an asymmetric disease?, Br J Obstet Gynaecol, 105, 1018, 10.1111/j.1471-0528.1998.tb10267.x · DOI
- Esinler, 2006, Outcome of in vitro fertilization/intracytoplasmic sperm injection after laparoscopic cystectomy for endometriomas, Fertil Steril, 85, 1730, 10.1016/j.fertnstert.2005.10.076 · DOI
- Yu, 2010, Laparoscopic ovarian cystectomy of endometriomas: surgeons' experience may affect ovarian reserve and live-born rate in infertile patients with in vitro fertilization-intracytoplasmic sperm injection, Eur J Obstet Gynecol Reprod Biol, 152, 172, 10.1016/j.ejogrb.2010.05.016 · DOI
- Lee, 1992, Simplified instrumentation for laparoscopic ovarian cystectomy, Chang Yi Xue Za Zhi, 15, 28
- 1997, Revised American society for reproductive medicine classification of endometriosis: 1996, Fertil Steril, 67, 817, 10.1016/S0015-0282(97)81391-X · DOI · Paper page
- Muzii, 2002, Laparoscopic excision of ovarian cysts: is the stripping technique a tissue-sparing procedure?, Fertil Steril, 77, 609, 10.1016/S0015-0282(01)03203-4 · DOI
- Romualdi, 2011, Follicular loss in endoscopic surgery for ovarian endometriosis: quantitative and qualitative observations, Fertil Steril, 96, 374, 10.1016/j.fertnstert.2011.05.078 · DOI
- Shi, 2011, Follicle loss after laparoscopic treatment of ovarian endometriotic cysts, Int J Gynaecol Obstet, 115, 277, 10.1016/j.ijgo.2011.07.026 · DOI
- Ragni, 2005, Damage to ovarian reserve associated with laparoscopic excision of endometriomas: a quantitative rather than a qualitative injury, Am J Obstet Gynecol, 193, 1908, 10.1016/j.ajog.2005.05.056 · DOI
- Benaglia, 2010, Rate of severe ovarian damage following surgery for endometriomas, Hum Reprod, 25, 678, 10.1093/humrep/dep464 · DOI
- Hirokawa, 2011, The post-operative decline in serum anti-Mullerian hormone correlates with the bilaterality and severity of endometriosis, Hum Reprod, 26, 904, 10.1093/humrep/der006 · DOI
- Alborzi, 2014, The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometriomas, Fertil Steril, 101, 427, 10.1016/j.fertnstert.2013.10.019 · DOI
- Seifer, 2002, Early follicular serum mullerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles, Fertil Steril, 77, 468, 10.1016/S0015-0282(01)03201-0 · DOI
- Lee, 2011, Effects of laparoscopic surgery on serum anti-mullerian hormone levels in reproductive-aged women with endometrioma, Gynecol Endocrinol, 27, 733, 10.3109/09513590.2010.538098 · DOI
- Sugita, 2013, One-year follow-up of serum antimullerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing damage to the ovarian reserve?, Fertil Steril, 100, 516, 10.1016/j.fertnstert.2013.03.032 · DOI · Paper page
Cited by
McDonnell, R., Gollow, J., Nathan, E., Doherty, D., Majumder, K., Wilkinson, E., McElhinney, B., Karthigasu, K., & Hart, R. (2025) · Gynecology and Minimally Invasive Therapy · doi:10.4103/gmit.gmit_156_23 · Cited by 6
Metadata
- Authors
- Yu, H.-T., Huang, H.-Y., Tseng, H.-J., Wang, C.-J., Lee, C.-L., & Soong, Y.-K.
- Affiliations
- Chang Gung University (TW)
- Corresponding author
- Wang, Chin-Jung
- Venue
- Biomedical Journal
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 40
- Issue
- 5
- Pages
- 295-299
- ISSN
- 2319-4170 (ISSN-L)
- PMC
- PMC6138598
- OpenAlex
- W2767545563
- Cited by
- 16
- References
- 0
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 3 · 2017: 1
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biomedical Journal (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Chang Gung Medical Foundation (CPRPG3A0011)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- endometrioma, bilateral endometrioma, laparoscopic cystectomy, in vitro fertilization, intracytoplasmic sperm injection, ovarian reserve, ovarian response, oocyte retrieval, pregnancy outcomes, infertility, implantation rate, live birth rate
- MeSH terms
- Endometriosis, Female, Humans, Laparoscopy, Pregnancy, Pregnancy Outcome, Retrospective Studies, Cystectomy, Sperm Injections, Intracytoplasmic, Ovarian Reserve
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