CoChat
Sign Up
Cited by 74

The DOI matches its Crossref record.

Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis

Francisco, Gerardo D., Li, Zhong, Albright, J.Donald, Eudy, Nancy H., Katz, Alan H., Petersen, Peter J., Labthavikul, Pornpen, Singh, Guy, Yang, Youjun, Rasmussen, Beth A., Lin, Yang-I, Mansour, Tarek S.·2004·Bioorganic & Medicinal Chemistry Letters
DOI 10.1016/j.bmcl.2003.09.082
Open this paper in CoChat — free account

Abstract

Over 50 phenyl thiazolyl urea and carbamate derivatives were synthesized for evaluation as new inhibitors of bacterial cell-wall biosynthesis. Many of them demonstrated good activity against MurA and MurB and gram-positive bacteria including MRSA, VRE and PRSP. 3,4-Difluorophenyl 5-cyanothiazolylurea (3p) with clog P of 2.64 demonstrated antibacterial activity against both gram-positive and gram-negative bacteria.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.bmcl.2003.09.082

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Some similarities exist between our molecules and known inhibitors of bacterial cell wall biosynthesis and lipid biosynthesis.

    “Some similarities exist between our molecules and known inhibitors of bacterial cell wall biosynthesis (Li et al., 2003; Francisco et al., 2004) and lipid biosynthesis (Russell, 2004).”

    From Small Molecule Fluoride Toxicity Agonists (2015) · cites this paper as Francisco et al., 2004

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 14

  1. Bugg, 1992, Nat. Prod. Rep., 9, 199, 10.1039/np9920900199 · DOI
  2. Isono, 1985, J. Antibiotics, 38, 1617, 10.7164/antibiotics.38.1617 · DOI
  3. Kimura, 1998, J. Antibiotics, 51, 1099, 10.7164/antibiotics.51.1099 · DOI
  4. Green, 2002, Expert Opin. Ther. Targets, 6, 1, 10.1517/14728222.6.1.1 · DOI
  5. Li, 2003, Bioorg. Med. Chem. Lett., 13, 2591, 10.1016/S0960-894X(03)00471-2 · DOI
  6. Frishberg, M. D. US Patent 4,324,899, 1982; Chem. Abstr. 1982, 97, 25169. · DOI
  7. Chem. Abstr. 1984, 101, 211130.
  8. Athmani, 1992, Tetrahedron, 48, 7689, 10.1016/S0040-4020(01)90380-1 · DOI
  9. Joseph-McCarthey, 2003, Proteins, 51, 172, 10.1002/prot.10266 · DOI
  10. Benson, 1997, Biochemistry, 36, 806, 10.1021/bi962221g · DOI
  11. Makino, 1997, J. Comput. Chem., 18, 1812, 10.1002/(SICI)1096-987X(19971115)18:14<1812::AID-JCC10>3.0.CO;2-H · DOI
  12. McMartin, 1997, J. Comp. Aided Mol. Des., 11, 333, 10.1023/A:1007907728892 · DOI
  13. Proctor, 2002, Antimicrob. Agents Chemother., 46, 2333, 10.1128/AAC.46.8.2333-2336.2002 · DOI
  14. Beaver, 1957, J. Am. Chem. Soc., 79, 1236, 10.1021/ja01562a053 · DOI

Cited by

Sorted by citations

Metadata

Authors
Francisco, G. D., Li, Z., Albright, J. D., Eudy, N. H., Katz, A. H., Petersen, P. J., Labthavikul, P., Singh, G., Yang, Y., Rasmussen, B. A., Lin, Y.-I., & Mansour, T. S.
Venue
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier BV
Published
2004-01
Volume
14
Issue
1
Pages
235-238
ISSN
0960-894X
DOI
10.1016/j.bmcl.2003.09.082
Cited by
74
References
0
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review