Small fat droplets interact with structural filaments in macrophages with cytoskeletal dysfunction contributing to perturbed phagocytosis and migration
Open accessIntegrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Small lipid droplets interfere with structural filaments, leading to cytoskeletal dysfunction and reduced phagocytic activity.
“Furthermore, in microglia, small LDs can interfere with structural filaments, leading to cytoskeletal dysfunction and reduced phagocytic activity (53).”
From Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model (2025) · cites this paper as [53]
Cited by
Sorted by citations
Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model
Wu, X., Miller, J. A., Lee, B. T. K., Wang, Y., & Ruedl, C. (2025) · Science Advances · doi:10.1126/sciadv.adq6038 · Cited by 67 · see citing works
“Furthermore, in microglia, small LDs can interfere with structural filaments, leading to cytoskeletal dysfunction and reduced phagocytic activity ( 53 ).”
- Authors
- Tobin, M. P., Ivanovska, I. L., & Discher, D. E.
- Affiliations
- University of Pennsylvania (US)
- Venue
- Biophysical Journal
- Publisher
- Elsevier BV
- Published
- 2023-02
- Volume
- 122
- Issue
- 3
- Pages
- 409a
- ISSN
- 0006-3495 (ISSN-L)
- OpenAlex
- W4319915724
- Cited by
- 1
- References
- 0
- Citations by year
- 2025: 1
- FWCI
- 0.10
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biophysical Journal (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
- Keywords
- lipid droplets, macrophages, phagocytosis, macrophage migration, cytoskeleton, F-actin, myosin II, oleic acid, tumor-associated macrophages, foam cells, cancer cell spheroids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
