miR-21 alleviates secondary blood–brain barrier damage after traumatic brain injury in rats

Ge, Xintong; Han, Zhaoli; Chen, Fanglian; Wang, Haichen; Zhang, Baoliang; Jiang, Rongcai; Lei, Ping; Zhang, Jianning

doi:10.1016/j.brainres.2015.01.009

miR-21 alleviates secondary blood–brain barrier damage after traumatic brain injury in rats

Our recent studies have identified increased expression of miR-21 in brain following traumatic brain injury (TBI), which alleviated brain edema that related to the blood-brain barrier (BBB) leakage. To analyze the potential effect of miR-21 on secondary BBB damage after TBI, we employed the fluid…