The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation–contraction coupling in the heart
Open accessAbstract
Calcium (Ca(2+)) is the central second messenger in the translation of electrical signals into mechanical activity of the heart. This highly coordinated process, termed excitation-contraction coupling or ECC, is based on Ca(2+)-induced Ca(2+) release from the sarcoplasmic reticulum (SR). In recent years it has become increasingly clear that several Ca(2+)-dependent proteins contribute to the fine tuning of ECC. One of these is the Ca(2+)/calmodulin-dependent protein kinase (CaMK) of which CaMKII is the predominant cardiac isoform. During ECC CaMKII phosphorylates several Ca(2+) handling proteins with multiple functional consequences. CaMKII may also be co-localized to distinct target proteins. CaMKII expression as well as activity are reported to be increased in heart failure and CaMKII overexpression can exert distinct and novel effects on ECC in the heart and in isolated myocytes of animals. In the present review we summarize important aspects of the role of CaMKII in ECC with an emphasis on recent novel findings.
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2 retracted
Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
Dzhura, I., Wu, Y., Colbran, R. J., Balser, J. R., & Anderson, M. E. (2000) · Nature Cell Biology · doi:10.1038/35004052 · Cited by 335
RetractedRETRACTED: L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII
Grueter, C. E., Abiria, S. A., Dzhura, I., Wu, Y., Ham, A.-J. L., Mohler, P. J., Anderson, M. E., & Colbran, R. J. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.07.006 · Cited by 184
RetractedCardiac excitation–contraction coupling
Bers, D. M. (2002) · Nature · doi:10.1038/415198a · Cited by 4,744
Self-citationPKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)
Marx, S. O., Reiken, S., Hisamatsu, Y., Jayaraman, T., Burkhoff, D., Rosemblit, N., & Marks, A. R. (2000) · Cell · doi:10.1016/s0092-8674(00)80847-8 · Cited by 1,978
Excitation-Contraction Coupling and Cardiac Contractile Force
Bers, D. M., & Zhu, Y. (2010) · Journal of Cardiovascular Disease Research · doi:10.1016/s0975-3583(10)11011-0 · Cited by 1,603
Self-citationExcitation-Contraction Coupling and Cardiac Contractile Force
Bers, D. M. (2001) · Developments in Cardiovascular Medicine · doi:10.1007/978-94-010-0658-3 · Cited by 1,548
Self-citationThe Multifunctional Calcium/Calmodulin-Dependent Protein Kinase: From Form to Function
Braun, A. P., & Schulman, H. (1995) · Annual Review of Physiology · doi:10.1146/annurev.ph.57.030195.002221 · Cited by 819
Excitation-Contraction Coupling and Cardiac Contractile Force
Bers, D. M. (1993) · Developments in Cardiovascular Medicine · doi:10.1007/978-94-017-1512-6 · Cited by 772
Self-citationAi, X., Curran, J. W., Shannon, T. R., Bers, D. M., & Pogwizd, S. M. (2005) · Circulation Research · doi:10.1161/01.res.0000194329.41863.89 · Cited by 697
Self-citationA Single Na + Channel Mutation Causing Both Long-QT and Brugada Syndromes
Bezzina, C., Veldkamp, M. W., van den Berg, M. P., Postma, A. V., Rook, M. B., Viersma, J.-W., van Langen, I. M., Tan-Sindhunata, G., Bink-Boelkens, M. T. E., van der Hout, A. H., et al. (1999) · Circulation Research · doi:10.1161/01.res.85.12.1206 · Cited by 656
Cited by
Backs, J., Backs, T., Neef, S., Kreusser, M. M., Lehmann, L. H., Patrick, D. M., Grueter, C. E., Qi, X., Richardson, J. A., Hill, J. A., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813013106 · Cited by 431
Self-citationDifferential Cardiac Remodeling in Preload Versus Afterload
Toischer, K., Rokita, A. G., Unsöld, B., Zhu, W., Kararigas, G., Sossalla, S., Reuter, S. P., Becker, A., Teucher, N., Seidler, T., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.943431 · Cited by 318
Self-citationSossalla, S., Fluschnik, N., Schotola, H., Ort, K. R., Neef, S., Schulte, T., Wittköpper, K., Renner, A., Schmitto, J. D., Gummert, J., et al. (2010) · Circulation Research · doi:10.1161/circresaha.110.220418 · Cited by 237
Self-citationStructural Insights into the Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)
Bhattacharyya, M., Karandur, D., & Kuriyan, J. (2020) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a035147 · Cited by 95
Metadata
- Authors
- Maier, L. S., & Bers, D. M.
- Venue
- Cardiovascular Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-03-01
- Volume
- 73
- Issue
- 4
- Pages
- 631-640
- ISSN
- 0008-6363 (ISSN-L)
- 1755-3245
- OpenAlex
- W1992290425
- Cited by
- 330
- References
- 73
- FWCI
- 10.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
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